A6TGI9 (A6TGI9_KLEP7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenylate cyclase RuleBase RU000604
EC=4.6.1.1 RuleBase RU000604

Gene names

Name:	cyaA EMBL ABR79673.1
Ordered Locus Names:	KPN78578_42490
ORF Names:	KPN_04305 EMBL ABR79673.1

Organism

Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP] EMBL ABR79673.1

Taxonomic identifier

272620 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella › Klebsiella pneumoniae › Klebsiella pneumoniae subsp. pneumoniae

Protein attributes

Sequence length	850 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP = 3',5'-cyclic AMP + diphosphate. RuleBase RU000604
Subcellular location	Cytoplasm By similarity RuleBase RU000604.
Sequence similarities	Belongs to the adenylyl cyclase class-1 family. RuleBase RU004184

Ontologies

Keywords
Biological process	cAMP biosynthesis RuleBase RU000604
Molecular function	Lyase RuleBase RU000604
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	adenylate cyclase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6TGI9 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: CD6A99E02CD00314	FASTA	850	97,571
	10 20 30 40 50 60 MYLYIETLKQ RLDAINQLRV DRALAAMGPA FQQVYSLLPT LLHYHHPLMP GYLDGNVPRG 70 80 90 100 110 120 ICLYTPDETQ RHYLEELELH RGMQTQEPPK GELPITGVYS MGSTSSVGQS CSSDLDIWVC 130 140 150 160 170 180 HQAWLDSEER QLLQRKCSLL ESWAASLGVE VSFFLIDENR FRHNESGSLG GEDCGSTQHI 190 200 210 220 230 240 LLLDEFYRTA VRLAGKRILW NMVPCDEEEH YDDYVMGLYA QGVLTPNEWL DLGGLSSLSA 250 260 270 280 290 300 EEYFGASLWQ LYKSIDSPYK AVLKTLLLEA YSWEYPNNRL LAKDIKQRLH DGEIVSFGLD 310 320 330 340 350 360 PYCMMLERVT TYLQAIEDET RLDLVRRCFY LKVCEKLSRE RACVGWRREV VSQLVNAWGW 370 380 390 400 410 420 DEKRLMMLDN RANWKIDEVR KAHNELLDAM MQSYRNLIRF ARRNNLSVSA SPQDIGVLTR 430 440 450 460 470 480 KLYAAFEALP GKVTLVNPQI SPDLSEPNLT FIHVPPGRAN RTGWYLYNRA PDMESIISHQ 490 500 510 520 530 540 PLEYNRYLNK LVAWAWFNGL LTSRTRLFIK GNGIVDLAKL QEMVADVSHH FPLRLPAPTP 550 560 570 580 590 600 KALYSPCEIR HLAIIVNLEY DPTAAFRNQV VHFDFRKLDV FSFGEEQKCL IGSVDLLYRN 610 620 630 640 650 660 SWNEVRTLHF NGEQAMIEAL KTILGKMHQD AAPPDSVEVF CYSQHLRGLI RTRVQQMISE 670 680 690 700 710 720 CIELRLSSTR QDTGRFKALR VSGQTWGLFF ERLNVSVQKL ENAIEFYGAI SHNKLHGLSV 730 740 750 760 770 780 QVETNHVKLP AVVDGFASEG IIQFFFEDAD NNDSGFNIYI LDESNRAEVY HHCEGSKEEL 790 800 810 820 830 840 VRDVSRFYSS SHDRFTYGSS FINFNLPQFY QIVEVDGRTQ VIPFRTQAIA AAIPTSQDVT 850 ASPVLQQRYS

References

[1]

The Klebsiella pneumonia Genome Sequencing Project McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000647 Genomic DNA. Translation: ABR79673.1.
RefSeq	YP_001337940.1. NC_009648.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	272620.KPN_04305.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABR79673; ABR79673; KPN_04305.
GeneID	5339383.
KEGG	kpn:KPN_04305.
PATRIC	20463072. VBIKlePne13394_4363.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3072.
HOGENOM	HOG000270910.
KO	K05851.
OMA	LWQLYKG.
ProtClustDB	PRK09450.
Family and domain databases
InterPro	IPR000274. Adenylate_cyclase_1. IPR024686. Adenylate_cyclase_1_CS. IPR024685. Adenylate_cyclase_1_N. [Graphical view]
Pfam	PF12633. Adenyl_cycl_N. 1 hit. PF01295. Adenylate_cycl. 1 hit. [Graphical view]
PIRSF	PIRSF001444. Adenylate_cycl. 1 hit.
PROSITE	PS01092. ADENYLATE_CYCLASE_1_1. 1 hit. PS01093. ADENYLATE_CYCLASE_1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6TGI9_KLEP7

Accession

Primary (citable) accession number: A6TGI9

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)