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A6TGE0

- A6TGE0_KLEP7

UniProt

A6TGE0 - A6TGE0_KLEP7

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei146 – 1461UniRule annotation
    Active sitei554 – 5541UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciKPNE272620:GKDC-4282-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotationImported
    ORF Names:KPN_04245Imported
    OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
    Taxonomic identifieri272620 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000000265: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi272620.KPN_04245.

    Structurei

    3D structure databases

    ProteinModelPortaliA6TGE0.
    SMRiA6TGE0. Positions 12-891.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2352.
    HOGENOMiHOG000238648.
    KOiK01595.
    OMAiISCQHYR.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6TGE0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRWGVWGNMN EQYSALRSNV SMLGKVLGDT IKDALGENIL DRVETIRKLS    50
    KSSRAGNEAN RQELLTTLQN LSNDELLPVA RAFSQFLNLA NTAEQYHSIS 100
    ANGEAASNPE VIARTLRKLK DQPNLNEETI KQAVESLSLE LVLTAHPTEI 150
    TRRTLIHKMV EVNNCLKQLD NKDIADYEHH QLMRRLRQLI AQSWHTDEIR 200
    KHRPSPVDEA KWGFAVVENS LWEGVPNYLR ELNEQLEANL GYQLPVDFVP 250
    VRFTSWMGGD RDGNPNVTAD ITRHVLLLSR WKATDLFLKD VQVLISELSM 300
    VECTDELRAL AGAEGAQEPY RYLMKKLRSQ LMETQAWLEA RLKGQKLPKP 350
    AGLITQNEQL WEPLYACYKS LQACGMGIIA NGELLDTLRR VKSFGVPLVR 400
    IDIRQESTRH TEALGEMTRY LGIGDYESWS EADKQAFLIR ELNSKRPLLP 450
    RQWEPSEETR EVLDTCKVIA EAPRGSIAAY VISMAKTPSD VLAVHLLLKE 500
    AGIGFALPVA PLFETLDDLN NANDVMTQLL NIDWYRGFIQ GKQMVMIGYS 550
    DSAKDAGVMA ASWAQYQAQD ALIKTCEKAG IELTLFHGRG GSIGRGGAPA 600
    HAALLSQPPG SLKGGLRVTE QGEMIRFKYG LPEVTISSLS LYTSAILEAN 650
    LLPPPEPKAE WRDIMAELSD VSCKMYRGYV RENKDFVPYF RSATPEQELG 700
    KLPLGSRPAK RRPTGGVESL RAIPWIFAWT QNRLMLPAWL GAGAALQKVV 750
    EGGKQSELEA MCRDWPFFST RLGMLEMVYS KADLWLAEYY DQRLVKPELW 800
    ALGSELRKLL AADINVVLAI ANDSHLMADL PWIAESIQLR NIYTDPLNVL 850
    QAELLHRSRQ AEEEGKDPDP RVEQALMVTI AGVAAGMRNT G 891
    Length:891
    Mass (Da):99,934
    Last modified:August 21, 2007 - v1
    Checksum:iAD82AC29CE687B80
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR79624.1.
    RefSeqiWP_015959215.1. NC_009648.1.
    YP_001337891.1. NC_009648.1.

    Genome annotation databases

    EnsemblBacteriaiABR79624; ABR79624; KPN_04245.
    GeneIDi5340603.
    KEGGikpn:KPN_04245.
    PATRICi20462948. VBIKlePne13394_4312.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR79624.1 .
    RefSeqi WP_015959215.1. NC_009648.1.
    YP_001337891.1. NC_009648.1.

    3D structure databases

    ProteinModelPortali A6TGE0.
    SMRi A6TGE0. Positions 12-891.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272620.KPN_04245.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR79624 ; ABR79624 ; KPN_04245 .
    GeneIDi 5340603.
    KEGGi kpn:KPN_04245.
    PATRICi 20462948. VBIKlePne13394_4312.

    Phylogenomic databases

    eggNOGi COG2352.
    HOGENOMi HOG000238648.
    KOi K01595.
    OMAi ISCQHYR.
    OrthoDBi EOG6TJ7T8.

    Enzyme and pathway databases

    BioCyci KPNE272620:GKDC-4282-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700721 / MGH 78578Imported.

    Entry informationi

    Entry nameiA6TGE0_KLEP7
    AccessioniPrimary (citable) accession number: A6TGE0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3