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A6TGE0

- A6TGE0_KLEP7

UniProt

A6TGE0 - A6TGE0_KLEP7

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei146 – 1461UniRule annotation
Active sitei554 – 5541UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-4282-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:KPN_04245Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi272620.KPN_04245.

Structurei

3D structure databases

ProteinModelPortaliA6TGE0.
SMRiA6TGE0. Positions 12-891.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiISCQHYR.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6TGE0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRWGVWGNMN EQYSALRSNV SMLGKVLGDT IKDALGENIL DRVETIRKLS
60 70 80 90 100
KSSRAGNEAN RQELLTTLQN LSNDELLPVA RAFSQFLNLA NTAEQYHSIS
110 120 130 140 150
ANGEAASNPE VIARTLRKLK DQPNLNEETI KQAVESLSLE LVLTAHPTEI
160 170 180 190 200
TRRTLIHKMV EVNNCLKQLD NKDIADYEHH QLMRRLRQLI AQSWHTDEIR
210 220 230 240 250
KHRPSPVDEA KWGFAVVENS LWEGVPNYLR ELNEQLEANL GYQLPVDFVP
260 270 280 290 300
VRFTSWMGGD RDGNPNVTAD ITRHVLLLSR WKATDLFLKD VQVLISELSM
310 320 330 340 350
VECTDELRAL AGAEGAQEPY RYLMKKLRSQ LMETQAWLEA RLKGQKLPKP
360 370 380 390 400
AGLITQNEQL WEPLYACYKS LQACGMGIIA NGELLDTLRR VKSFGVPLVR
410 420 430 440 450
IDIRQESTRH TEALGEMTRY LGIGDYESWS EADKQAFLIR ELNSKRPLLP
460 470 480 490 500
RQWEPSEETR EVLDTCKVIA EAPRGSIAAY VISMAKTPSD VLAVHLLLKE
510 520 530 540 550
AGIGFALPVA PLFETLDDLN NANDVMTQLL NIDWYRGFIQ GKQMVMIGYS
560 570 580 590 600
DSAKDAGVMA ASWAQYQAQD ALIKTCEKAG IELTLFHGRG GSIGRGGAPA
610 620 630 640 650
HAALLSQPPG SLKGGLRVTE QGEMIRFKYG LPEVTISSLS LYTSAILEAN
660 670 680 690 700
LLPPPEPKAE WRDIMAELSD VSCKMYRGYV RENKDFVPYF RSATPEQELG
710 720 730 740 750
KLPLGSRPAK RRPTGGVESL RAIPWIFAWT QNRLMLPAWL GAGAALQKVV
760 770 780 790 800
EGGKQSELEA MCRDWPFFST RLGMLEMVYS KADLWLAEYY DQRLVKPELW
810 820 830 840 850
ALGSELRKLL AADINVVLAI ANDSHLMADL PWIAESIQLR NIYTDPLNVL
860 870 880 890
QAELLHRSRQ AEEEGKDPDP RVEQALMVTI AGVAAGMRNT G
Length:891
Mass (Da):99,934
Last modified:August 21, 2007 - v1
Checksum:iAD82AC29CE687B80
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR79624.1.
RefSeqiYP_001337891.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR79624; ABR79624; KPN_04245.
GeneIDi5340603.
KEGGikpn:KPN_04245.
PATRICi20462948. VBIKlePne13394_4312.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR79624.1 .
RefSeqi YP_001337891.1. NC_009648.1.

3D structure databases

ProteinModelPortali A6TGE0.
SMRi A6TGE0. Positions 12-891.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272620.KPN_04245.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR79624 ; ABR79624 ; KPN_04245 .
GeneIDi 5340603.
KEGGi kpn:KPN_04245.
PATRICi 20462948. VBIKlePne13394_4312.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ISCQHYR.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci KPNE272620:GKDC-4282-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578Imported.

Entry informationi

Entry nameiA6TGE0_KLEP7
AccessioniPrimary (citable) accession number: A6TGE0
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3