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A6TGE0

- A6TGE0_KLEP7

UniProt

A6TGE0 - A6TGE0_KLEP7

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, KPN_04245
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei146 – 1461 By similarityUniRule annotation
Active sitei554 – 5541 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-4282-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:KPN_04245Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi272620.KPN_04245.

Structurei

3D structure databases

ProteinModelPortaliA6TGE0.
SMRiA6TGE0. Positions 12-891.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiISCQHYR.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6TGE0-1 [UniParc]FASTAAdd to Basket

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MRWGVWGNMN EQYSALRSNV SMLGKVLGDT IKDALGENIL DRVETIRKLS    50
KSSRAGNEAN RQELLTTLQN LSNDELLPVA RAFSQFLNLA NTAEQYHSIS 100
ANGEAASNPE VIARTLRKLK DQPNLNEETI KQAVESLSLE LVLTAHPTEI 150
TRRTLIHKMV EVNNCLKQLD NKDIADYEHH QLMRRLRQLI AQSWHTDEIR 200
KHRPSPVDEA KWGFAVVENS LWEGVPNYLR ELNEQLEANL GYQLPVDFVP 250
VRFTSWMGGD RDGNPNVTAD ITRHVLLLSR WKATDLFLKD VQVLISELSM 300
VECTDELRAL AGAEGAQEPY RYLMKKLRSQ LMETQAWLEA RLKGQKLPKP 350
AGLITQNEQL WEPLYACYKS LQACGMGIIA NGELLDTLRR VKSFGVPLVR 400
IDIRQESTRH TEALGEMTRY LGIGDYESWS EADKQAFLIR ELNSKRPLLP 450
RQWEPSEETR EVLDTCKVIA EAPRGSIAAY VISMAKTPSD VLAVHLLLKE 500
AGIGFALPVA PLFETLDDLN NANDVMTQLL NIDWYRGFIQ GKQMVMIGYS 550
DSAKDAGVMA ASWAQYQAQD ALIKTCEKAG IELTLFHGRG GSIGRGGAPA 600
HAALLSQPPG SLKGGLRVTE QGEMIRFKYG LPEVTISSLS LYTSAILEAN 650
LLPPPEPKAE WRDIMAELSD VSCKMYRGYV RENKDFVPYF RSATPEQELG 700
KLPLGSRPAK RRPTGGVESL RAIPWIFAWT QNRLMLPAWL GAGAALQKVV 750
EGGKQSELEA MCRDWPFFST RLGMLEMVYS KADLWLAEYY DQRLVKPELW 800
ALGSELRKLL AADINVVLAI ANDSHLMADL PWIAESIQLR NIYTDPLNVL 850
QAELLHRSRQ AEEEGKDPDP RVEQALMVTI AGVAAGMRNT G 891
Length:891
Mass (Da):99,934
Last modified:August 21, 2007 - v1
Checksum:iAD82AC29CE687B80
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR79624.1.
RefSeqiWP_015959215.1. NC_009648.1.
YP_001337891.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR79624; ABR79624; KPN_04245.
GeneIDi5340603.
KEGGikpn:KPN_04245.
PATRICi20462948. VBIKlePne13394_4312.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR79624.1 .
RefSeqi WP_015959215.1. NC_009648.1.
YP_001337891.1. NC_009648.1.

3D structure databases

ProteinModelPortali A6TGE0.
SMRi A6TGE0. Positions 12-891.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272620.KPN_04245.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR79624 ; ABR79624 ; KPN_04245 .
GeneIDi 5340603.
KEGGi kpn:KPN_04245.
PATRICi 20462948. VBIKlePne13394_4312.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ISCQHYR.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci KPNE272620:GKDC-4282-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578.

Entry informationi

Entry nameiA6TGE0_KLEP7
AccessioniPrimary (citable) accession number: A6TGE0
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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