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Protein

HTH-type transcriptional activator RhaS

Gene

rhaS

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Activates expression of the rhaBAD and rhaT operons.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi190 – 209H-T-H motifUniRule annotationAdd BLAST20
DNA bindingi239 – 262H-T-H motifUniRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processRhamnose metabolism, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator RhaSUniRule annotation
Alternative name(s):
L-rhamnose operon regulatory protein RhaSUniRule annotation
Gene namesi
Name:rhaSUniRule annotation
Ordered Locus Names:KPN78578_41690
ORF Names:KPN_04214
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000000265 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000687061 – 278HTH-type transcriptional activator RhaSAdd BLAST278

Interactioni

Subunit structurei

Binds DNA as a dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei241Interaction with sigma-70UniRule annotation1
Sitei250Interaction with sigma-70UniRule annotation1

Protein-protein interaction databases

STRINGi272620.KPN_04214

Structurei

3D structure databases

ProteinModelPortaliA6TGA9
SMRiA6TGA9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4107S4Z Bacteria
ENOG410XT8S LUCA
HOGENOMiHOG000290513
KOiK02855
OMAiGHYPSHW

Family and domain databases

Gene3Di2.60.120.10, 1 hit
HAMAPiMF_01534 HTH_type_RhaS, 1 hit
InterProiView protein in InterPro
IPR003313 AraC-bd
IPR009057 Homeobox-like_sf
IPR037923 HTH-like
IPR018060 HTH_AraC
IPR018062 HTH_AraC-typ_CS
IPR014710 RmlC-like_jellyroll
IPR020449 Tscrpt_reg_HTH_AraC-type
IPR023609 Tscrpt_reg_HTH_RhaS
PfamiView protein in Pfam
PF02311 AraC_binding, 1 hit
PF12833 HTH_18, 1 hit
PRINTSiPR00032 HTHARAC
SMARTiView protein in SMART
SM00342 HTH_ARAC, 1 hit
SUPFAMiSSF46689 SSF46689, 2 hits
SSF51215 SSF51215, 1 hit
PROSITEiView protein in PROSITE
PS00041 HTH_ARAC_FAMILY_1, 1 hit
PS01124 HTH_ARAC_FAMILY_2, 1 hit

Sequencei

Sequence statusi: Complete.

A6TGA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTILHSTDFF KAGISTVAIE PRLPQSAFPE HHHDFHEIVI VEQGSGIHVF
60 70 80 90 100
NGQPYTIGGG SVCFIRDHDR HLYEHTDNLC LTNVLYRAPD AFRFLAGVSQ
110 120 130 140 150
LLPQEQEGNY PSHWRVNQTV LQQVRHIVAQ IEAVGSDTDT HAVASREILF
160 170 180 190 200
MQLLVLLRKS SLAEEATNND ARLNQLLAWL EDHFAQEICW EEVAAQFSLS
210 220 230 240 250
LRTLHRQLKQ QTGLTPQRYL NRVRLMKARH LLRHSDESVT DIAYRCGFGD
260 270
SNHFSTLFRR EFDWSPRDIR QGRDAILQ
Length:278
Mass (Da):32,001
Last modified:August 21, 2007 - v1
Checksum:iA211EE38A8B69FAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA Translation: ABR79593.1
RefSeqiWP_002882888.1, NC_009648.1

Genome annotation databases

EnsemblBacteriaiABR79593; ABR79593; KPN_04214
KEGGikpn:KPN_04214

Similar proteinsi

Entry informationi

Entry nameiRHAS_KLEP7
AccessioniPrimary (citable) accession number: A6TGA9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: April 25, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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