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Protein

Ribosomal RNA small subunit methyltransferase J

Gene

rsmJ

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the guanosine in position 1516 of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1516) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1516) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei171 – 1711S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-3899-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase JUniRule annotation (EC:2.1.1.242UniRule annotation)
Alternative name(s):
16S rRNA m2G1516 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferaseUniRule annotation
Gene namesi
Name:rsmJUniRule annotation
Ordered Locus Names:KPN78578_38250
ORF Names:KPN_03862
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000000265 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 250250Ribosomal RNA small subunit methyltransferase JPRO_0000316257Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_03862.

Structurei

3D structure databases

ProteinModelPortaliA6TFB5.
SMRiA6TFB5. Positions 1-249.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni101 – 1022S-adenosyl-L-methionine bindingUniRule annotation
Regioni117 – 1182S-adenosyl-L-methionine bindingUniRule annotation
Regioni153 – 1542S-adenosyl-L-methionine bindingUniRule annotation

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RsmJ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105FFN. Bacteria.
ENOG410XPRJ. LUCA.
HOGENOMiHOG000218236.
KOiK15984.
OMAiSSRYDIY.
OrthoDBiEOG657J92.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01523. 16SrRNA_methyltr_J.
InterProiIPR007536. 16SrRNA_methylTrfase_J.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF04445. SAM_MT. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

A6TFB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKICLIDETG AGDGALSVLA ARWGLEQDDD NPMALALTTE HLELRKRDEP
60 70 80 90 100
KLGGIFVDFV GGAMAHRRKF GGGRGEAVAK AVGIKGDYLP DVVDATAGLG
110 120 130 140 150
RDAFVLASVG CRVRMLERNP VVAALLDDGL ARGYADAEIG GWLQERLQLI
160 170 180 190 200
HASSLTALTD ITPRPQVVYL DPMFPHKQKS ALVKKEMRVF QSLVGPDLDA
210 220 230 240 250
DGLLAPARQL ATKRVVVKRP DYAPPLADVA TPNAVVTKGH RFDIYAGTPA
Length:250
Mass (Da):26,786
Last modified:August 21, 2007 - v1
Checksum:i5D13BA5D04AA9965
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR79249.1.
RefSeqiWP_004173956.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR79249; ABR79249; KPN_03862.
KEGGikpn:KPN_03862.
PATRICi20462159. VBIKlePne13394_3924.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR79249.1.
RefSeqiWP_004173956.1. NC_009648.1.

3D structure databases

ProteinModelPortaliA6TFB5.
SMRiA6TFB5. Positions 1-249.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272620.KPN_03862.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR79249; ABR79249; KPN_03862.
KEGGikpn:KPN_03862.
PATRICi20462159. VBIKlePne13394_3924.

Phylogenomic databases

eggNOGiENOG4105FFN. Bacteria.
ENOG410XPRJ. LUCA.
HOGENOMiHOG000218236.
KOiK15984.
OMAiSSRYDIY.
OrthoDBiEOG657J92.

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-3899-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01523. 16SrRNA_methyltr_J.
InterProiIPR007536. 16SrRNA_methylTrfase_J.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF04445. SAM_MT. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578.

Entry informationi

Entry nameiRSMJ_KLEP7
AccessioniPrimary (citable) accession number: A6TFB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: November 11, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.