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A6TEM9 (A6TEM9_KLEP7) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase 2 HAMAP MF_00106

EC=4.2.1.8 HAMAP MF_00106
Alternative name(s):
D-mannonate hydrolase 2 HAMAP MF_00106
Gene names
Name:uxuA2 HAMAP MF_00106
Ordered Locus Names:KPN78578_35890
ORF Names:KPN_03620 EMBL ABR79013.1
OrganismKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP]
Taxonomic identifier272620 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106 SAAS SAAS004628

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106 SAAS SAAS004628

Sequence similarities

Belongs to the mannonate dehydratase family. HAMAP MF_00106

Ontologies

Keywords
   Molecular functionLyase HAMAP MF_00106 SAAS SAAS004628
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A6TEM9 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 5658F45E5B7B62BF

FASTA35440,494
        10         20         30         40         50         60 
MQMTMRWFGP EEDKISLEHI RQVPGVEGVV GALYDVAVGE VWPVDKIERL VGQAHAAGLK 

        70         80         90        100        110        120 
MEVIESVNIH DDIKIGLPTR ERYIANYQQT IRNLARFGVK VICYNFMPVF DWMKTDMNYV 

       130        140        150        160        170        180 
LPDGSLTMAF EKKDIDKRLE DVVKEVLENS NGFALPGWEP ERLAEVQTLF AKYSAVDDQK 

       190        200        210        220        230        240 
LRENLVYFLQ AVIPVCEEVG VKMAIHPDDP PYSIFGLPRV VKNRDDLDWI CRAVDSPANG 

       250        260        270        280        290        300 
ITLCTGSIAE DPDNDVYAIL AEFTRRKRIH FAHVRNIKLM QDKDFYECAH PSEYGSLDMY 

       310        320        330        340        350 
KVMQALYDNG FDGYIRPDHG RFIWGETGRP GYGLFDRALG VTYLKGLWEA LSKR 

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References

[1]McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000647 Genomic DNA. Translation: ABR79013.1.
RefSeqYP_001337280.1. NC_009648.1.

3D structure databases

ProteinModelPortalA6TEM9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6TEM9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5339789.
GenomeReviewsGene locus KPN78578_35890 in contig CP000647_GR.
KEGGkpn:KPN_03620.
PATRIC20461665. VBIKlePne13394_3682.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1312.
HOGENOMHBG585927.
OMADIKLGKP.
ProtClustDBPRK03906.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6TEM9_KLEP7
AccessionPrimary (citable) accession number: A6TEM9
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)