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Protein
Submitted name:

Putative major Intrinsic Protein channel, glycerol diffusion

Gene

glpF

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-3522-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative major Intrinsic Protein channel, glycerol diffusionImported
Gene namesi
Name:glpFImported
ORF Names:KPN_03485Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000000265 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3423HelicalSequence analysisAdd
BLAST
Transmembranei46 – 7934HelicalSequence analysisAdd
BLAST
Transmembranei86 – 10823HelicalSequence analysisAdd
BLAST
Transmembranei145 – 16622HelicalSequence analysisAdd
BLAST
Transmembranei178 – 20225HelicalSequence analysisAdd
BLAST
Transmembranei222 – 25130HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_03485.

Structurei

3D structure databases

ProteinModelPortaliA6TE96.
SMRiA6TE96. Positions 6-259.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105D8C. Bacteria.
COG0580. LUCA.
HOGENOMiHOG000288287.
KOiK02440.
OMAiWNETKDA.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6TE96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQTSTLTGQ CVAEFLGTGL LIFFGAGCVA ALRVAGASFG QWEISIIWGL
60 70 80 90 100
GVAMAIYLTA GVSGAHLNPA VTIALWLFAC FERRKVLPFI VAQTAGAFCA
110 120 130 140 150
AALVYGLYRQ LFLDLEQSQH IVRGTAASLN LAGVFSTYPH PHITFIQAFA
160 170 180 190 200
VETTITAILM AMIMALTDDG NGIPRGPLAP LLIGLLIAVL GASMGPLTGF
210 220 230 240 250
ALNPARDFGP KLFTSLAGWG SIAFTGGLAI PYFLVPLLAP VVGAIIGAFL
260
YRKLIGRHLP CECGIDE
Length:267
Mass (Da):28,029
Last modified:August 21, 2007 - v1
Checksum:i5127EBCEA8D97B01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR78880.1.
RefSeqiWP_015959037.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR78880; ABR78880; KPN_03485.
KEGGikpn:KPN_03485.
PATRICi20461387. VBIKlePne13394_3545.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR78880.1.
RefSeqiWP_015959037.1. NC_009648.1.

3D structure databases

ProteinModelPortaliA6TE96.
SMRiA6TE96. Positions 6-259.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272620.KPN_03485.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR78880; ABR78880; KPN_03485.
KEGGikpn:KPN_03485.
PATRICi20461387. VBIKlePne13394_3545.

Phylogenomic databases

eggNOGiENOG4105D8C. Bacteria.
COG0580. LUCA.
HOGENOMiHOG000288287.
KOiK02440.
OMAiWNETKDA.

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-3522-MONOMER.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA6TE96_KLEP7
AccessioniPrimary (citable) accession number: A6TE96
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.