Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A6TDU9

- SPEB_KLEP7

UniProt

A6TDU9 - SPEB_KLEP7

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Agmatinase

Gene

speB

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of putrescine from agmatine.UniRule annotation

Catalytic activityi

Agmatine + H2O = putrescine + urea.UniRule annotation

Cofactori

Manganese.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi126 – 1261ManganeseUniRule annotation
Metal bindingi149 – 1491ManganeseUniRule annotation
Metal bindingi151 – 1511ManganeseUniRule annotation
Metal bindingi153 – 1531ManganeseUniRule annotation
Metal bindingi230 – 2301ManganeseUniRule annotation
Metal bindingi232 – 2321ManganeseUniRule annotation

GO - Molecular functioni

  1. agmatinase activity Source: UniProtKB-HAMAP
  2. manganese ion binding Source: InterPro

GO - Biological processi

  1. putrescine biosynthetic process from arginine Source: UniProtKB-UniPathway
  2. spermidine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Polyamine biosynthesis, Putrescine biosynthesis, Spermidine biosynthesis

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-3373-MONOMER.
UniPathwayiUPA00534; UER00287.

Names & Taxonomyi

Protein namesi
Recommended name:
AgmatinaseUniRule annotation (EC:3.5.3.11UniRule annotation)
Alternative name(s):
Agmatine ureohydrolaseUniRule annotation
Short name:
AUHUniRule annotation
Gene namesi
Name:speBUniRule annotation
Ordered Locus Names:KPN78578_33090
ORF Names:KPN_03373
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306AgmatinasePRO_1000024282Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_03373.

Structurei

3D structure databases

ProteinModelPortaliA6TDU9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family. Agmatinase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0010.
HOGENOMiHOG000204320.
KOiK01480.
OMAiKPDYSLY.
OrthoDBiEOG6R2GW5.

Family and domain databases

Gene3Di3.40.800.10. 1 hit.
HAMAPiMF_01418. SpeB.
InterProiIPR023694. Agmatinase.
IPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERiPTHR11358. PTHR11358. 1 hit.
PfamiPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFiPIRSF036979. Arginase. 1 hit.
TIGRFAMsiTIGR01230. agmatinase. 1 hit.
PROSITEiPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6TDU9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTLGHQYDN SLVSNAFGFL RLPMNFMPYE SDADWVITGV PFDMATSGRA
60 70 80 90 100
GGRHGPAAIR QVSTNLAWEH NRFPWNFDMR ERLNVVDCGD LVYAFGDARE
110 120 130 140 150
MSEKLQAHAE KLLAAGKRML SFGGDHFVTL PLLRAHAKHF GKMALVHFDA
160 170 180 190 200
HTDTYANGCE FDHGTMFYTA PNEGLIDPNH SVQIGIRTEF DKDNGFTVLD
210 220 230 240 250
AGQVNDRSVD DVIAQVKQIV GDMPVYLTFD IDCLDPAFAP GTGTPVIGGL
260 270 280 290 300
TSDRAIKLVR GLKDLNIVGM DVVEVAPAYD QSEITALAAA TLALEMLYIQ

AAKKGE
Length:306
Mass (Da):33,514
Last modified:August 21, 2007 - v1
Checksum:i233B7D0B5BAD3CB0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR78770.1.
RefSeqiYP_001337000.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR78770; ABR78770; KPN_03373.
GeneIDi5341870.
KEGGikpn:KPN_03373.
PATRICi20461088. VBIKlePne13394_3398.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR78770.1 .
RefSeqi YP_001337000.1. NC_009648.1.

3D structure databases

ProteinModelPortali A6TDU9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272620.KPN_03373.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR78770 ; ABR78770 ; KPN_03373 .
GeneIDi 5341870.
KEGGi kpn:KPN_03373.
PATRICi 20461088. VBIKlePne13394_3398.

Phylogenomic databases

eggNOGi COG0010.
HOGENOMi HOG000204320.
KOi K01480.
OMAi KPDYSLY.
OrthoDBi EOG6R2GW5.

Enzyme and pathway databases

UniPathwayi UPA00534 ; UER00287 .
BioCyci KPNE272620:GKDC-3373-MONOMER.

Family and domain databases

Gene3Di 3.40.800.10. 1 hit.
HAMAPi MF_01418. SpeB.
InterProi IPR023694. Agmatinase.
IPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view ]
PANTHERi PTHR11358. PTHR11358. 1 hit.
Pfami PF00491. Arginase. 1 hit.
[Graphical view ]
PIRSFi PIRSF036979. Arginase. 1 hit.
TIGRFAMsi TIGR01230. agmatinase. 1 hit.
PROSITEi PS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578.

Entry informationi

Entry nameiSPEB_KLEP7
AccessioniPrimary (citable) accession number: A6TDU9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: October 1, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3