Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A6TC50

- A6TC50_KLEP7

UniProt

A6TC50 - A6TC50_KLEP7

Protein

Cysteine synthase

Gene

cysK

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. cysteine synthase activity Source: UniProtKB-EC
    2. hydrolase activity Source: UniProtKB-KW
    3. transferase activity Source: UniProtKB-KW

    GO - Biological processi

    1. cysteine biosynthetic process from serine Source: InterPro

    Keywords - Molecular functioni

    HydrolaseImported, TransferaseUniRule annotation

    Keywords - Biological processi

    Amino-acid biosynthesis, Cysteine biosynthesisUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciKPNE272620:GKDC-2761-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cysteine synthaseUniRule annotation (EC:2.5.1.47UniRule annotation)
    Gene namesi
    Name:cysKImported
    ORF Names:KPN_02761Imported
    OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
    Taxonomic identifieri272620 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000000265: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi272620.KPN_02761.

    Structurei

    3D structure databases

    ProteinModelPortaliA6TC50.
    SMRiA6TC50. Positions 2-323.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cysteine synthase/cystathionine beta-synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0031.
    HOGENOMiHOG000217394.
    KOiK01738.
    OMAiVKCRIGS.
    OrthoDBiEOG6Q2SP8.

    Family and domain databases

    InterProiIPR005856. Cys_synthKM.
    IPR005859. CysK.
    IPR001216. P-phosphate_BS.
    IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
    [Graphical view]
    PfamiPF00291. PALP. 1 hit.
    [Graphical view]
    SUPFAMiSSF53686. SSF53686. 1 hit.
    TIGRFAMsiTIGR01139. cysK. 1 hit.
    TIGR01136. cysKM. 1 hit.
    PROSITEiPS00901. CYS_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6TC50-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKIFEDNSL TIGHTPLVRL NRIGNGRILA KVESRNPSFS VKCRIGANMI    50
    WDAEKRGVLK PGVELVEPTS GNTGIALAYV AAARGYKLTL TMPETMSIER 100
    RKLLKALGAN LVLTEGAKGM KGAIQKAEEI VASNPEQFLL LQQFSNPANP 150
    EIHEKTTGPE IWEDTDGQVD VFISGVGTGG TLTGVSRYIK NTKGKKDLIT 200
    VAVEPTDSPV IAQALAGEEL KPGPHKIQGI GAGFIPGNLD LKLVDKVIGI 250
    TNEEAISTAR RLMEEEGILA GISSGAAVAA ALKLQEDEAF TNKNIVVILP 300
    SSGERYLSTA LFADLFTEKE LQQ 323
    Length:323
    Mass (Da):34,558
    Last modified:August 21, 2007 - v1
    Checksum:i66245EAB1E2A37A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR78171.1.
    RefSeqiYP_001336401.1. NC_009648.1.

    Genome annotation databases

    EnsemblBacteriaiABR78171; ABR78171; KPN_02761.
    GeneIDi5342507.
    KEGGikpn:KPN_02761.
    PATRICi20459822. VBIKlePne13394_2778.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR78171.1 .
    RefSeqi YP_001336401.1. NC_009648.1.

    3D structure databases

    ProteinModelPortali A6TC50.
    SMRi A6TC50. Positions 2-323.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272620.KPN_02761.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR78171 ; ABR78171 ; KPN_02761 .
    GeneIDi 5342507.
    KEGGi kpn:KPN_02761.
    PATRICi 20459822. VBIKlePne13394_2778.

    Phylogenomic databases

    eggNOGi COG0031.
    HOGENOMi HOG000217394.
    KOi K01738.
    OMAi VKCRIGS.
    OrthoDBi EOG6Q2SP8.

    Enzyme and pathway databases

    BioCyci KPNE272620:GKDC-2761-MONOMER.

    Family and domain databases

    InterProi IPR005856. Cys_synthKM.
    IPR005859. CysK.
    IPR001216. P-phosphate_BS.
    IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
    [Graphical view ]
    Pfami PF00291. PALP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53686. SSF53686. 1 hit.
    TIGRFAMsi TIGR01139. cysK. 1 hit.
    TIGR01136. cysKM. 1 hit.
    PROSITEi PS00901. CYS_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700721 / MGH 78578Imported.

    Entry informationi

    Entry nameiA6TC50_KLEP7
    AccessioniPrimary (citable) accession number: A6TC50
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3