A6TC50 (A6TC50_KLEP7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Name:	cysK EMBL ABR78171.1
Ordered Locus Names:	KPN78578_27100
ORF Names:	KPN_02761 EMBL ABR78171.1

Organism

Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP] EMBL ABR78171.1

Taxonomic identifier

272620 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella › Klebsiella pneumoniae › Klebsiella pneumoniae subsp. pneumoniae

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Hydrolase EMBL ABR78171.1 Transferase RuleBase RU003985
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular_function	cysteine synthase activity Inferred from electronic annotation. Source: EC hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6TC50 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 66245EAB1E2A37A1	FASTA	323	34,558
	10 20 30 40 50 60 MSKIFEDNSL TIGHTPLVRL NRIGNGRILA KVESRNPSFS VKCRIGANMI WDAEKRGVLK 70 80 90 100 110 120 PGVELVEPTS GNTGIALAYV AAARGYKLTL TMPETMSIER RKLLKALGAN LVLTEGAKGM 130 140 150 160 170 180 KGAIQKAEEI VASNPEQFLL LQQFSNPANP EIHEKTTGPE IWEDTDGQVD VFISGVGTGG 190 200 210 220 230 240 TLTGVSRYIK NTKGKKDLIT VAVEPTDSPV IAQALAGEEL KPGPHKIQGI GAGFIPGNLD 250 260 270 280 290 300 LKLVDKVIGI TNEEAISTAR RLMEEEGILA GISSGAAVAA ALKLQEDEAF TNKNIVVILP 310 320 SSGERYLSTA LFADLFTEKE LQQ

References

[1]

The Klebsiella pneumonia Genome Sequencing Project McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000647 Genomic DNA. Translation: ABR78171.1.
RefSeq	YP_001336401.1. NC_009648.1.
3D structure databases
ProteinModelPortal	A6TC50.
SMR	A6TC50. Positions 2-323.
ModBase	Search...
Protein-protein interaction databases
STRING	272620.KPN_02761.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABR78171; ABR78171; KPN_02761.
GeneID	5342507.
KEGG	kpn:KPN_02761.
PATRIC	20459822. VBIKlePne13394_2778.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0031.
HOGENOM	HOG000217394.
KO	K01738.
OMA	NSFTIGH.
ProtClustDB	PRK10717.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR005856. Cys_synthKM. IPR005859. CysK. IPR001926. Trp_syn_b_sub_like_PLP_eny_SF. [Graphical view]
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR01139. cysK. 1 hit. TIGR01136. cysKM. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6TC50_KLEP7

Accession

Primary (citable) accession number: A6TC50

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)