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A6TC33

- GLK_KLEP7

UniProt

A6TC33 - GLK_KLEP7

Protein

Glucokinase

Gene

glk

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi8 – 136ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glucokinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciKPNE272620:GKDC-2738-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
    Alternative name(s):
    Glucose kinaseUniRule annotation
    Gene namesi
    Name:glkUniRule annotation
    Ordered Locus Names:KPN78578_26930
    ORF Names:KPN_02738
    OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
    Taxonomic identifieri272620 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000000265: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 321321GlucokinasePRO_1000050970Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272620.KPN_02738.

    Structurei

    3D structure databases

    ProteinModelPortaliA6TC33.
    SMRiA6TC33. Positions 2-321.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the bacterial glucokinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0837.
    HOGENOMiHOG000274469.
    KOiK00845.
    OMAiDWVEMTN.
    OrthoDBiEOG64BQ47.

    Family and domain databases

    HAMAPiMF_00524. Glucokinase.
    InterProiIPR003836. Glucokinase.
    [Graphical view]
    PfamiPF02685. Glucokinase. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00749. glk. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6TC33-1 [UniParc]FASTAAdd to Basket

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    MTKFALVGDV GGTNARLALC DLASGEISRA KTYSGLDYPS LEAVVRVYLE    50
    EHQVTVNEGC IAIACPITGD WVAMTNHTWA FSIAEMKRNL GFAHLEIIND 100
    FTAVSMAIPM LKAEHLIQFG GSAPVAGKPI AVYGAGTGLG VAHLVHVDKR 150
    WVSLPGEGGH VDFAPNSEEE GIILEELRAE LGHVSAERVL SGPGLVNLYR 200
    AIVKSDGRLP ENLQPREVTE RALADSCTDC RRALSLFCVI MGRFGGNLAL 250
    TLGTFGGVYI AGGIVPRFLE FFKASGFRGG FEDKGRFKAY VQDIPVYLIV 300
    HDNPGLLGSG AHLRQTLGQV L 321
    Length:321
    Mass (Da):34,422
    Last modified:August 21, 2007 - v1
    Checksum:i73F82D688259986D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR78154.1.
    RefSeqiYP_001336384.1. NC_009648.1.

    Genome annotation databases

    EnsemblBacteriaiABR78154; ABR78154; KPN_02738.
    GeneIDi5338195.
    KEGGikpn:KPN_02738.
    PATRICi20459776. VBIKlePne13394_2761.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR78154.1 .
    RefSeqi YP_001336384.1. NC_009648.1.

    3D structure databases

    ProteinModelPortali A6TC33.
    SMRi A6TC33. Positions 2-321.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272620.KPN_02738.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR78154 ; ABR78154 ; KPN_02738 .
    GeneIDi 5338195.
    KEGGi kpn:KPN_02738.
    PATRICi 20459776. VBIKlePne13394_2761.

    Phylogenomic databases

    eggNOGi COG0837.
    HOGENOMi HOG000274469.
    KOi K00845.
    OMAi DWVEMTN.
    OrthoDBi EOG64BQ47.

    Enzyme and pathway databases

    BioCyci KPNE272620:GKDC-2738-MONOMER.

    Family and domain databases

    HAMAPi MF_00524. Glucokinase.
    InterProi IPR003836. Glucokinase.
    [Graphical view ]
    Pfami PF02685. Glucokinase. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00749. glk. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700721 / MGH 78578.

    Entry informationi

    Entry nameiGLK_KLEP7
    AccessioniPrimary (citable) accession number: A6TC33
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3