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Protein

Glucokinase

Gene

glk

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-2738-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:KPN78578_26930
ORF Names:KPN_02738
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321GlucokinasePRO_1000050970Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_02738.

Structurei

3D structure databases

ProteinModelPortaliA6TC33.
SMRiA6TC33. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

A6TC33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKFALVGDV GGTNARLALC DLASGEISRA KTYSGLDYPS LEAVVRVYLE
60 70 80 90 100
EHQVTVNEGC IAIACPITGD WVAMTNHTWA FSIAEMKRNL GFAHLEIIND
110 120 130 140 150
FTAVSMAIPM LKAEHLIQFG GSAPVAGKPI AVYGAGTGLG VAHLVHVDKR
160 170 180 190 200
WVSLPGEGGH VDFAPNSEEE GIILEELRAE LGHVSAERVL SGPGLVNLYR
210 220 230 240 250
AIVKSDGRLP ENLQPREVTE RALADSCTDC RRALSLFCVI MGRFGGNLAL
260 270 280 290 300
TLGTFGGVYI AGGIVPRFLE FFKASGFRGG FEDKGRFKAY VQDIPVYLIV
310 320
HDNPGLLGSG AHLRQTLGQV L
Length:321
Mass (Da):34,422
Last modified:August 21, 2007 - v1
Checksum:i73F82D688259986D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR78154.1.
RefSeqiWP_002913377.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR78154; ABR78154; KPN_02738.
KEGGikpn:KPN_02738.
PATRICi20459776. VBIKlePne13394_2761.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR78154.1.
RefSeqiWP_002913377.1. NC_009648.1.

3D structure databases

ProteinModelPortaliA6TC33.
SMRiA6TC33. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272620.KPN_02738.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR78154; ABR78154; KPN_02738.
KEGGikpn:KPN_02738.
PATRICi20459776. VBIKlePne13394_2761.

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-2738-MONOMER.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578.

Entry informationi

Entry nameiGLK_KLEP7
AccessioniPrimary (citable) accession number: A6TC33
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: July 22, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.