A6TBY3 (A6TBY3_KLEP7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase HAMAP MF_00020

Gene names

Name:	ackA HAMAP MF_00020 EMBL ABR78104.1
Ordered Locus Names:	KPN78578_26430
ORF Names:	KPN_02687 EMBL ABR78104.1

Organism

Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP]

Taxonomic identifier

272620 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020 RuleBase RU003835

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00020 SAAS SAAS000890 RuleBase RU003835 EMBL ABR78104.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6TBY3 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 36F7F119E97DDA1F	FASTA	400	43,274
	10 20 30 40 50 60 MSSKLVLVLN CGSSSLKFAI LDAVNGDEYL SGLAECFHLP EARIKWKMDG SKQEAELGAG 70 80 90 100 110 120 AAHSEALNFI VNTILAQKPE LSAQLTAIGH RIVHGGEKYT SSVVIDESVI QGIKDAASFA 130 140 150 160 170 180 PLHNPAHLIG IAEALKSFPH LKDKNVAVFD TAFHQTMPEE SYLYALPYSL YKEHGVRRYG 190 200 210 220 230 240 AHGTSHFYVT QEAAKILNKP VEELNIITCH LGNGGSVSAI RNGKCVDTSM GLTPLEGLVM 250 260 270 280 290 300 GTRSGDIDPA IIFHLHDTLG MSVDAINKML TKESGLLGLT EVTSDCRYVE DNYQEKADAK 310 320 330 340 350 360 RAMDVYCHRL AKYIGSYTAL MDGRLDAVIF TGGIGENAAM VRELSLGKLG VLGFEVDHER 370 380 390 400 NLAARFGKSG FINKEGTRPA VVIPTNEELV IAQDASRLTA

References

[1]	McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000647 Genomic DNA. Translation: ABR78104.1.
RefSeq	YP_001336334.1. NC_009648.1.
3D structure databases
ProteinModelPortal	A6TBY3.
ModBase	Search...
Protein-protein interaction databases
STRING	A6TBY3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5338822.
GenomeReviews	Gene locus KPN78578_26430 in contig CP000647_GR.
KEGG	kpn:KPN_02687.
PATRIC	20459670. VBIKlePne13394_2709.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	IVFHLHD.
ProtClustDB	PRK00180.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6TBY3_KLEP7

Accession

Primary (citable) accession number: A6TBY3

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)