A6TBU4 (GLPB_KLEP7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B
Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	KPN78578_26040
ORF Names:	KPN_02648

Organism

Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP]

Taxonomic identifier

272620 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella › Klebsiella pneumoniae › Klebsiella pneumoniae subsp. pneumoniae

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753
Subunit structure	Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycerol catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway glycerol-3-phosphate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 419	419	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753		PRO_1000046607

Sequences

	Sequence		Length	Mass (Da)
	A6TBU4 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 4FEED392A8F8579E	FASTA	419	45,106
	10 20 30 40 50 60 MKFDCAIIGG GLAGLLCGLA LNQHGLRSVI ISRGQSALHF SSASLDLLSA LPNGDHVTDV 70 80 90 100 110 120 AQGLQQLAEQ LPEHPYSRLG AEAVLKYATQ TEALLAACGA VMQGDARRPH RRVTPLGTLR 130 140 150 160 170 180 PAWLSPLEVP VAPLPSQGAC LVGISGFADF QPHLAAAALG QHGVTAAAVE IELPLLDVLR 190 200 210 220 230 240 DNPTEFRAAN IARVLDDENM WPALHAALLP LAQQYDLLIM PACFGLADDR LYHWLQARLP 250 260 270 280 290 300 CPLRLLPTLP PSVPGMRLHS QLQRQFIREG GAWLAGDEVV KISHRQDAVE AVWTRNHGDI 310 320 330 340 350 360 ALRPRFTVLA SGSFFSNGLV ATRDSVREPI LGLDLHQTLP RESWYQRDFF ASQPWQRFGV 370 380 390 400 410 KTDALLRPLL GGQPFHNLFA IGSLLGGFDA IQLGCGGGVC AVTALHAARQ IHALAGGRP

References

[1]

The Klebsiella pneumonia Genome Sequencing Project McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000647 Genomic DNA. Translation: ABR78065.1.
RefSeq	YP_001336295.1. NC_009648.1.
3D structure databases
ProteinModelPortal	A6TBU4.
ModBase	Search...
Protein-protein interaction databases
STRING	272620.KPN_02648.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABR78065; ABR78065; KPN_02648.
GeneID	5342104.
KEGG	kpn:KPN_02648.
PATRIC	20459590. VBIKlePne13394_2669.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3075.
HOGENOM	HOG000278489.
KO	K00112.
OMA	FRSVNIS.
ProtClustDB	PRK05329.
Enzyme and pathway databases
UniPathway	UPA00618; UER00673.
Family and domain databases
HAMAP	MF_00753. Glycerol3P_GlpB.
InterPro	IPR003953. FAD_bind_dom. IPR009158. G3P_DH_GlpB_su. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_KLEP7

Accession

Primary (citable) accession number: A6TBU4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 21, 2007
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program