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Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpA

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: InterPro
  2. FMN binding Source: InterPro
  3. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
  2. polyol catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotation

Keywords - Ligandi

FlavoproteinUniRule annotation

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-2647-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:glpAImported
ORF Names:KPN_02647Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
  2. plasma membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_02647.

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004814.
KOiK00111.
OMAiMIAMNHR.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
IPR017752. G3P_DH_GlpA_su.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF04324. Fer2_BFD. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
TIGRFAMsiTIGR03377. glycerol3P_GlpA. 1 hit.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6TBU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGRLDSEVI IIGGGATGAG IARDCARRGL RTLLIERHDI ATGATGRNQG
60 70 80 90 100
LLHSGARYAV TDNESARECI SENRILRRIA RHCIEPTNGL FITLPEDDLA
110 120 130 140 150
WQQTFIDACQ QAGIEATPLS PQEALRREPA VNPTLLGAVQ VPDGTIDPFR
160 170 180 190 200
LTAANMLDAR EHGAQILTGC EVTGLLRRGD RVCGVQVYDR QLHQARTLYA
210 220 230 240 250
GMVVNAAGIW GQRIAEYADL RITMFPAKGS LLILDHRINN LVINRCRKPA
260 270 280 290 300
DADILVPGDT ISLIGTTSMH IPYDEIDDNR VTAAEVDTLL REGEKLAPVM
310 320 330 340 350
GRTRILRAYS GVRPLVASDN DPSGRGVSRG IVLLDHAQRD GMEGFITITG
360 370 380 390 400
GKLMTYRLMA EWATDAVCRK LGNTTPCTTA EAPLPGSQEP TESTLQKIIS
410 420 430 440 450
LPTPLRGSAV YRHGDRTPSW LGDSRQHRSL VCECEAVTAG EVKYAVENLA
460 470 480 490 500
VNTLLDLRRR TRIGMGTCQG ELCACRAAGL LQRFNVTTPA QSLTQLSEFL
510 520 530 540
NERWKGVQPI AWGDALRESE FTRWVYLGLC GLPQEHRDEV
Length:540
Mass (Da):59,112
Last modified:August 21, 2007 - v1
Checksum:i7ACD711F5AF282B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR78064.1.
RefSeqiWP_015958751.1. NC_009648.1.
YP_001336294.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR78064; ABR78064; KPN_02647.
KEGGikpn:KPN_02647.
PATRICi20459588. VBIKlePne13394_2668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR78064.1.
RefSeqiWP_015958751.1. NC_009648.1.
YP_001336294.1. NC_009648.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272620.KPN_02647.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR78064; ABR78064; KPN_02647.
KEGGikpn:KPN_02647.
PATRICi20459588. VBIKlePne13394_2668.

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004814.
KOiK00111.
OMAiMIAMNHR.
OrthoDBiEOG651SR7.

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-2647-MONOMER.

Family and domain databases

InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
IPR017752. G3P_DH_GlpA_su.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF04324. Fer2_BFD. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
TIGRFAMsiTIGR03377. glycerol3P_GlpA. 1 hit.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578Imported.

Entry informationi

Entry nameiA6TBU3_KLEP7
AccessioniPrimary (citable) accession number: A6TBU3
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 1, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.