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Protein
Submitted name:

Cytoplasmic alpha-amylase

Gene

amyA

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei235 – 2351NucleophileUniRule annotation
Active sitei265 – 2651Proton donorUniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-2419-MONOMER.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytoplasmic alpha-amylaseImported
Gene namesi
Name:amyAImported
ORF Names:KPN_02419Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_02419.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000094847.
KOiK01176.
OMAiFFHWYYP.
OrthoDBiEOG65QWH3.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

A6TB71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNPTLLQCF HWYYPTGGEL WPEVEALAPS LNEIGINMVW LPPAYKGASG
60 70 80 90 100
GYSVGYDTYD LFDLGEFDQK GSVATKYGDK AQLLAAINAL KEHNIAVLLD
110 120 130 140 150
VVVNHKMGAD EKEALRVQRV DEQDRTQIDE EIIECEAWTR YTFPVRAGQY
160 170 180 190 200
SQFVWDYKCF SGIDHIENPT EDGVFKIVND YTGEGWNEQV DDELGNFDYL
210 220 230 240 250
MGANIDFRNH AVTEEIKYWA RWVMEQTGCD GFRLDAVKHI PAWFYKAWIE
260 270 280 290 300
HVQEVAPQPL FIVAEYWSHE VEKLQQYIDL VEGKTMLFDA PLQMKFHEAS
310 320 330 340 350
RQGRDYDMSQ IFSGTLVEAD PFHAVTLVTN HDTQPLQALE APVEPWFKPL
360 370 380 390 400
AYALILLREN GVPSVFYADL FGASYEDTGG DGETYAIEMP VIEQLHELID
410 420 430 440 450
ARQRFAHGVQ TLWFDHPNCI AFSRSGTDDD PGCVVIMSNG DEGEKTLTLG
460 470 480 490
ENYGNKRWRD FLGNREEIVE TDGEGCATFT CNGGSVSVWV LEEVL
Length:495
Mass (Da):56,235
Last modified:August 21, 2007 - v1
Checksum:i467D72A83A02BD6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR77842.1.
RefSeqiYP_001336072.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR77842; ABR77842; KPN_02419.
KEGGikpn:KPN_02419.
PATRICi20459134. VBIKlePne13394_2447.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR77842.1.
RefSeqiYP_001336072.1. NC_009648.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272620.KPN_02419.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR77842; ABR77842; KPN_02419.
KEGGikpn:KPN_02419.
PATRICi20459134. VBIKlePne13394_2447.

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000094847.
KOiK01176.
OMAiFFHWYYP.
OrthoDBiEOG65QWH3.

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-2419-MONOMER.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578Imported.

Entry informationi

Entry nameiA6TB71_KLEP7
AccessioniPrimary (citable) accession number: A6TB71
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 1, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.