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A6TAK7

- A6TAK7_KLEP7

UniProt

A6TAK7 - A6TAK7_KLEP7

Protein

Thymidine kinase

Gene

tdk

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciKPNE272620:GKDC-2200-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkImported
    ORF Names:KPN_02200Imported
    OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
    Taxonomic identifieri272620 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000000265: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi272620.KPN_02200.

    Structurei

    3D structure databases

    ProteinModelPortaliA6TAK7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.

    Phylogenomic databases

    eggNOGiCOG1435.
    HOGENOMiHOG000076391.
    KOiK00857.
    OMAiNERYIAM.
    OrthoDBiEOG69D3J2.

    Family and domain databases

    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6TAK7-1 [UniParc]FASTAAdd to Basket

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    MRTVVYTAEI DDRFGAGKVS SRIGLSSPAR LYNPQTSLFD DIAAEHQLKP    50
    IHCVLVDESQ FLTREQVHEL SEVVDTLDIP VLCYGLRTDF RGELFTGSQY 100
    LLAWSDKLVE LKTICFCGRK ASMVLRLDQE GRPYNEGEQV VIGGNERYVS 150
    VCRKHYKEAL SVGSLTKVQN QHRPC 175
    Length:175
    Mass (Da):19,797
    Last modified:August 21, 2007 - v1
    Checksum:iCCE53167E903DE53
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR77628.1.
    RefSeqiYP_001335858.1. NC_009648.1.

    Genome annotation databases

    EnsemblBacteriaiABR77628; ABR77628; KPN_02200.
    GeneIDi5341805.
    KEGGikpn:KPN_02200.
    PATRICi20458692. VBIKlePne13394_2231.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR77628.1 .
    RefSeqi YP_001335858.1. NC_009648.1.

    3D structure databases

    ProteinModelPortali A6TAK7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272620.KPN_02200.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR77628 ; ABR77628 ; KPN_02200 .
    GeneIDi 5341805.
    KEGGi kpn:KPN_02200.
    PATRICi 20458692. VBIKlePne13394_2231.

    Phylogenomic databases

    eggNOGi COG1435.
    HOGENOMi HOG000076391.
    KOi K00857.
    OMAi NERYIAM.
    OrthoDBi EOG69D3J2.

    Enzyme and pathway databases

    BioCyci KPNE272620:GKDC-2200-MONOMER.

    Family and domain databases

    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700721 / MGH 78578Imported.

    Entry informationi

    Entry nameiA6TAK7_KLEP7
    AccessioniPrimary (citable) accession number: A6TAK7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3