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A6TAK7

- A6TAK7_KLEP7

UniProt

A6TAK7 - A6TAK7_KLEP7

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Protein

Thymidine kinase

Gene

tdk

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-2200-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkImported
ORF Names:KPN_02200Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_02200.

Structurei

3D structure databases

ProteinModelPortaliA6TAK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1435.
HOGENOMiHOG000076391.
KOiK00857.
OMAiNERYIAM.
OrthoDBiEOG69D3J2.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6TAK7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRTVVYTAEI DDRFGAGKVS SRIGLSSPAR LYNPQTSLFD DIAAEHQLKP
60 70 80 90 100
IHCVLVDESQ FLTREQVHEL SEVVDTLDIP VLCYGLRTDF RGELFTGSQY
110 120 130 140 150
LLAWSDKLVE LKTICFCGRK ASMVLRLDQE GRPYNEGEQV VIGGNERYVS
160 170
VCRKHYKEAL SVGSLTKVQN QHRPC
Length:175
Mass (Da):19,797
Last modified:August 21, 2007 - v1
Checksum:iCCE53167E903DE53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR77628.1.
RefSeqiYP_001335858.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR77628; ABR77628; KPN_02200.
GeneIDi5341805.
KEGGikpn:KPN_02200.
PATRICi20458692. VBIKlePne13394_2231.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR77628.1 .
RefSeqi YP_001335858.1. NC_009648.1.

3D structure databases

ProteinModelPortali A6TAK7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272620.KPN_02200.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR77628 ; ABR77628 ; KPN_02200 .
GeneIDi 5341805.
KEGGi kpn:KPN_02200.
PATRICi 20458692. VBIKlePne13394_2231.

Phylogenomic databases

eggNOGi COG1435.
HOGENOMi HOG000076391.
KOi K00857.
OMAi NERYIAM.
OrthoDBi EOG69D3J2.

Enzyme and pathway databases

BioCyci KPNE272620:GKDC-2200-MONOMER.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578Imported.

Entry informationi

Entry nameiA6TAK7_KLEP7
AccessioniPrimary (citable) accession number: A6TAK7
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: November 26, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3