Reviewed,
UniProtKB/Swiss-Prot A6TAC8 (MHPB_KLEP7)
Last modified
November 25, 2008.
Version 14.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase EC=1.13.11.16 | ||||||
| Gene names |
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| Organism | Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 272620 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella |
Protein attributes
| Sequence length | 314 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively By similarity. |
| Catalytic activity | 3-(2,3-dihydroxyphenyl)propanoate + O(2) = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate. 2,3-dihydroxicinnamic acid + O(2) = 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate. |
| Cofactor | Fe(2+) ion By similarity. |
| Pathway | Aromatic compound metabolism; 3-phenylpropionic acid degradation. |
| Subunit structure | Homotetramer By similarity. |
| Sequence similarities | Belongs to the ligB/mhpB extradiol dioxygenase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Aromatic hydrocarbons catabolism |
| Ligand | Iron |
| Molecular function | Dioxygenase Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | aromatic compound catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | 2,3-dihydroxy-phenylpropionate 1,2-dioxygenase activity Inferred from electronic annotation. Source: HAMAP 3-carboxyethylcatechol 2,3-dioxygenase activityInferred from electronic annotation. Source: EC electron carrier activityInferred from electronic annotation. Source: InterPro ferrous iron bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000647 Genomic DNA. Translation: ABR77549.1. | |
| RefSeq | YP_001335779.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 5340517. |
| GenomeReviews | Gene locus KPN78578_20880 in contig CP000647_GR. |
| KEGG | kpn:KPN_02121. |
Organism-specific databases | |
| CMR | Search... |
Family and domain databases | |
| HAMAP | MF_01653. [Tree] |
| InterPro | IPR004183. Xdiol_dOase_3B. [Graphical view] |
| Gene3D | G3DSA:3.40.830.10. Xdiol_dOase_3B. 2 hits. |
| Pfam | PF02900. LigB. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MHPB_KLEP7 | ||||||||
| Accession | Primary (citable) accession number: A6TAC8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


