Reviewed,
UniProtKB/Swiss-Prot A6T9H1 (PQQC_KLEP7)
Last modified
November 3, 2009.
Version 18.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Pyrroloquinoline-quinone synthase EC=1.3.3.11 Alternative name(s): Coenzyme PQQ synthesis protein C Pyrroloquinoline quinone biosynthesis protein C | ||||||
| Gene names |
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| Organism | Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 272620 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella |
Protein attributes
| Sequence length | 251 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. |
| Catalytic activity | 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654 |
| Pathway | Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654 |
| Sequence similarities | Belongs to the pqqC family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | PQQ biosynthesis |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW pyrroloquinoline quinone biosynthetic processInferred from electronic annotation. Source: HAMAP |
| Molecular function | pyrroloquinoline-quinone synthase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 251 | 251 | Pyrroloquinoline-quinone synthase HAMAP MF_00654 | PRO_1000061670 | |||
Sequences
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References
| [1] | McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000647 Genomic DNA. Translation: ABR77242.1. | |
| RefSeq | YP_001335472.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A6T9H1. |
Genome annotation databases | |
| GeneID | 5342367. |
| GenomeReviews | Gene locus KPN78578_17810 in contig CP000647_GR. |
| KEGG | kpn:KPN_01811. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| OMA | DSWPQHY. |
Family and domain databases | |
| HAMAP | MF_00654. [Tree] |
| InterPro | IPR016084. Haem_Oase-like_multi-hlx. IPR011845. PQQ_synth_PqqC. IPR004305. TENA/THI4/PQQ_synth_PqqC. [Graphical view] |
| Gene3D | G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit. |
| Pfam | PF03070. TENA_THI-4. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR02111. PQQ_syn_pqqC. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PQQC_KLEP7 | ||||||||
| Accession | Primary (citable) accession number: A6T9H1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


