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A6T900

- UXAB_KLEP7

UniProt

A6T900 - UXAB_KLEP7

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Protein

Altronate oxidoreductase

Gene
uxaB, KPN78578_16100, KPN_01640
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 2912NAD By similarityAdd
BLAST

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. tagaturonate reductase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-1640-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductase (EC:1.1.1.58)
Alternative name(s):
Tagaturonate dehydrogenase
Tagaturonate reductase
Gene namesi
Name:uxaB
Ordered Locus Names:KPN78578_16100
ORF Names:KPN_01640
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 483483Altronate oxidoreductaseUniRule annotationPRO_1000044706Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_01640.

Structurei

3D structure databases

ProteinModelPortaliA6T900.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0246.
HOGENOMiHOG000029586.
KOiK00041.
OMAiHNTFCST.
OrthoDBiEOG6CVVB8.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.

Sequencei

Sequence statusi: Complete.

A6T900-1 [UniParc]FASTAAdd to Basket

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MKTLNRRDFP GAQYPDRIIQ FGEGNFLRAF VDWQIDLLNE HTDLNAGIVV    50
VRPIATDFPP SLNTQDGLYT TIIRGLNEQG EAVSDARLIR SVNREISAYA 100
DFDAFLRLAH NPEMRFVFSN TTEAGISYHA GDRFDDAPPV SYPAKLTRLL 150
FERYQHFAGA ADKGWVIIPC ELIDYNGEAL QALVLRYASE WELPQAFITW 200
LTSANTFCST LVDRIVTGYP RDEVAALEAQ TGYKDAFLDT AEHFYLFVIQ 250
GPASLAAELR LDKLPLNVRI VDDIKPYKER KVAILNGAHT ALVPVAFQAG 300
IDTVGEAMND AEICAFVEKA IYDEIIPVLD LPRDELVSFA SAVTGRFRNP 350
YIKHQLLSIA LNGMTKYRTR ILPQLLAGQK AHGALPPRLT FALAALIAFY 400
RGERDGESYP VQDDADWISR YQTLWARHRD GQMSTRELVT AVLSVADHWQ 450
QDLSQTPGLV ELVTADLDAI LTCGMRDAVK PLC 483
Length:483
Mass (Da):54,042
Last modified:August 21, 2007 - v1
Checksum:i41BA1BF5D4B90137
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR77071.1.
RefSeqiWP_015958391.1. NC_009648.1.
YP_001335301.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR77071; ABR77071; KPN_01640.
GeneIDi5339125.
KEGGikpn:KPN_01640.
PATRICi20457560. VBIKlePne13394_1668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR77071.1 .
RefSeqi WP_015958391.1. NC_009648.1.
YP_001335301.1. NC_009648.1.

3D structure databases

ProteinModelPortali A6T900.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272620.KPN_01640.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR77071 ; ABR77071 ; KPN_01640 .
GeneIDi 5339125.
KEGGi kpn:KPN_01640.
PATRICi 20457560. VBIKlePne13394_1668.

Phylogenomic databases

eggNOGi COG0246.
HOGENOMi HOG000029586.
KOi K00041.
OMAi HNTFCST.
OrthoDBi EOG6CVVB8.

Enzyme and pathway databases

UniPathwayi UPA00246 .
BioCyci KPNE272620:GKDC-1640-MONOMER.

Family and domain databases

Gene3Di 1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPi MF_00670. Altron_oxidoreduct.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48179. SSF48179. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578.

Entry informationi

Entry nameiUXAB_KLEP7
AccessioniPrimary (citable) accession number: A6T900
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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