Skip Header

Contribute Send feedback
Read comments (?) or add your own

A6T8T5 (A6T8T5_KLEP7) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Dithiobiotin synthetase EMBL ABR77006.1
Gene names
Name:bioD EMBL ABR77006.1
Ordered Locus Names:KPN78578_15450
ORF Names:KPN_01575 EMBL ABR77006.1
OrganismKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP]
Taxonomic identifier272620 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472

Catalytic activity

ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472

Cofactor

Magnesium By similarity. SAAS SAAS004472

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472

Subcellular location

Cytoplasm By similarity SAAS SAAS004472.

Sequences

Sequence LengthMass (Da)Tools
A6T8T5 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 02A8CB774E88FCAB

FASTA23124,928
        10         20         30         40         50         60 
MFKRFFITGT DTSVGKTVVS RALLQALAAR GKSVAGYKPV AKGSKETPDG LRNKDALVLQ 

        70         80         90        100        110        120 
SVSTLALPYE AVNPIALSED ESSVAHSCPI NYGLLSDGLQ RLAAQVEHVV VEGTGGWRSL 

       130        140        150        160        170        180 
MNDLRPLSEW VVQEQLPVLM VVGIQEGCIN HALLTAQAIA NDGLPLIGWV ANRINPGLAH 

       190        200        210        220        230 
YAEIIDVLSK KLPAPLIGEL PYLPRAEQRE LSRYVDLDML GNVMAIDRIP A

« Hide

References

[1]McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000647 Genomic DNA. Translation: ABR77006.1.
RefSeqYP_001335236.1. NC_009648.1.

3D structure databases

ProteinModelPortalA6T8T5.
SMRA6T8T5. Positions 3-220.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6T8T5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5342346.
GenomeReviewsGene locus KPN78578_15450 in contig CP000647_GR.
KEGGkpn:KPN_01575.
PATRIC20457428. VBIKlePne13394_1602.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0132.
HOGENOMHBG650065.
OMAINPGLSH.
ProtClustDBPRK12374.

Family and domain databases

HAMAPMF_00336. BioD.
[Tree]
InterProIPR002586. CbiA_P_synth.
IPR004472. DTB_synth_BioD.
[Graphical view]
KOK01935.
PfamPF01656. CbiA. 1 hit.
[Graphical view]
PIRSFPIRSF006755. DTB_synth. 1 hit.
TIGRFAMsTIGR00347. BioD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6T8T5_KLEP7
AccessionPrimary (citable) accession number: A6T8T5
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info