A6T8R4 (A6T8R4_KLEP7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase 1 HAMAP MF_00212
EC=1.1.5.4 HAMAP MF_00212

Alternative name(s):
MQO 1 HAMAP MF_00212
Malate dehydrogenase [quinone] 1 HAMAP MF_00212

Gene names

Name:	mqo1 HAMAP MF_00212
Ordered Locus Names:	KPN78578_15240
ORF Names:	KPN_01554 EMBL ABR76985.1

Organism

Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP]

Taxonomic identifier

272620 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212 SAAS SAAS006231
Cofactor	FAD By similarity. HAMAP MF_00212 SAAS SAAS006231
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212 SAAS SAAS006231
Sequence similarities	Belongs to the MQO family. HAMAP MF_00212

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle HAMAP MF_00212 SAAS SAAS006231
Ligand	FAD HAMAP MF_00212 SAAS SAAS006231 Flavoprotein HAMAP MF_00212 SAAS SAAS006231
Molecular function	Oxidoreductase HAMAP MF_00212 SAAS SAAS006231
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6T8R4 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: B0E6A7A24641F9A6	FASTA	548	60,003
	10 20 30 40 50 60 MKKTIISLTA LAMFVSAATH AEADTSKKTD FLLIGGGIMS ASLGTWLQAL QPDWDLTMVE 70 80 90 100 110 120 KLDGVALESS NGWNNAGTGH SANMELNYTP ERADGSIDVS KALDINEQFM ISRQFWSAQV 130 140 150 160 170 180 KRGILHDPHS FINSTPHMSF VWGDNVDYLQ KRYNALQQTT LFQGMKFSTD HAQIKQWAPL 190 200 210 220 230 240 VMEGRDPQQK VAATWTPVGT DVNYGEITRQ LIGSLKKNNH FTLQTSSEVT DFKRNADNSW 250 260 270 280 290 300 HVTIKNVQSG EAQTIDAKYV FIGAGGGALK LLQKTGIPEA DNYAGFPVGG SFLMTENPAV 310 320 330 340 350 360 TAQHLEKVYG QASVGAPPMS VPHLDARYLD GKRVVLFGPF ATFSTKFLKN GSFFDLLSTT 370 380 390 400 410 420 TTNNVLPMTH VGLDNFDLVK YLVSQVMLSD DDRFAALKEY YPDARKEDWK LIQAGQRVQI 430 440 450 460 470 480 IKKDAEKGGV LKLGTEVVVD QQKTISALLG ASPGASTAAP ITLNVLKQMF PQQFNSPEWQ 490 500 510 520 530 540 SRIHAIVPSY GQKLNGNVAL TQQVWDDTAA TLQLTKPPVI QMPAAAPTAT AKPAETPREA SPQHDMAL

References

[1]	McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000647 Genomic DNA. Translation: ABR76985.1.
RefSeq	YP_001335215.1. NC_009648.1.
3D structure databases
ProteinModelPortal	A6T8R4.
ModBase	Search...
Protein-protein interaction databases
STRING	A6T8R4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5340522.
GenomeReviews	Gene locus KPN78578_15240 in contig CP000647_GR.
KEGG	kpn:KPN_01554.
PATRIC	20457382. VBIKlePne13394_1579.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	HSANMEL.
ProtClustDB	PRK05257.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6T8R4_KLEP7

Accession

Primary (citable) accession number: A6T8R4

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)