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Reviewed, UniProtKB/Swiss-Prot A6T7R0 (MSRB_KLEP7)

Last modified November 3, 2009. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Peptide methionine sulfoxide reductase msrB
    EC=1.8.4.12
Alternative name(s):
    Peptide-methionine (R)-S-oxide reductase
Gene names
Name: msrB
Ordered Locus Names: KPN78578_11700
ORF Names: KPN_01198
OrganismKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP]
Taxonomic identifier272620 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

Protein attributes

Sequence length137 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400

Cofactor

Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity.

Sequence similarities

Belongs to the msrB Met sulfoxide reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 137136Peptide methionine sulfoxide reductase msrB HAMAP MF_01400
PRO_1000068273

Sites

Active site1181Nucleophile By similarity
Metal binding461Zinc By similarity
Metal binding491Zinc By similarity
Metal binding951Zinc By similarity
Metal binding981Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A6T7R0-1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 1D6ECACED2F665CC

FASTA13715,292
        10         20         30         40         50         60 
MANKPTPEEL KNGLSEMQFY VTQHHGTEPP FTGRLLHNKK NGVYHCLVCD APLFNSQTKY 

        70         80         90        100        110        120 
DSGCGWPSFY EPVSAEAIRY LTDNSHGMQR IEIRCGNCDA HLGHVFPDGP QPTGERYCVN 

       130 
SASLSFTDEQ NGEQIKG 

« Hide

References

[1]McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000647 Genomic DNA. Translation: ABR76631.1.
RefSeqYP_001334861.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA6T7R0.

Genome annotation databases

GeneID5339785.
GenomeReviewsGene locus KPN78578_11700 in contig CP000647_GR.
KEGGkpn:KPN_01198.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAFTGRYWD.

Family and domain databases

HAMAPMF_01400.
[Tree]
InterProIPR002579. Methionine_sulphoxide_MsrB.
[Graphical view]
Gene3DG3DSA:2.170.150.20. MsrB. 1 hit.
PfamPF01641. SelR. 1 hit.
[Graphical view]
ProDomPD004057. DUF25. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00357. MsrB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMSRB_KLEP7
AccessionPrimary (citable) accession number: A6T7R0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents