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Protein

FMN reductase (NADH) RutF

Gene

rutF

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.UniRule annotation

Catalytic activityi

FMNH2 + NAD+ = FMN + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN, NAD

Names & Taxonomyi

Protein namesi
Recommended name:
FMN reductase (NADH) RutFUniRule annotation (EC:1.5.1.42UniRule annotation)
Alternative name(s):
FMN reductaseUniRule annotation
NADH-flavin reductase RutFUniRule annotation
NADH:flavin oxidoreductaseUniRule annotation
Gene namesi
Name:rutFUniRule annotation
Ordered Locus Names:KPN78578_10070
ORF Names:KPN_01033
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000000265 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004030291 – 164FMN reductase (NADH) RutFAdd BLAST164

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_01033.

Structurei

3D structure databases

ProteinModelPortaliA6T797.
SMRiA6T797.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107YAQ. Bacteria.
COG1853. LUCA.
HOGENOMiHOG000115783.
KOiK09024.
OMAiWFDRGYH.

Family and domain databases

Gene3Di2.30.110.10. 1 hit.
HAMAPiMF_00833. RutF. 1 hit.
InterProiIPR002563. Flavin_Rdtase-like_dom.
IPR019917. RutF.
IPR012349. Split_barrel_FMN-bd.
[Graphical view]
PfamiPF01613. Flavin_Reduct. 1 hit.
[Graphical view]
SMARTiSM00903. Flavin_Reduct. 1 hit.
[Graphical view]
SUPFAMiSSF50475. SSF50475. 1 hit.
TIGRFAMsiTIGR03615. RutF. 1 hit.

Sequencei

Sequence statusi: Complete.

A6T797-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELTDKASFR DAMAHVGAAV NIITTDGPAG RAGFTASAVC SVTDTPPTLL
60 70 80 90 100
VCLNRSASVW PVFSEHHTLC VNTLAAGQEA LSTLFGGKTA MDERFAAADW
110 120 130 140 150
QTGATGCPRL EAALVSFDCR IDQRVSVGTH DILFCHVVAI TRHPEPRGLM
160
WFDRGYHTLM RPAC
Length:164
Mass (Da):17,634
Last modified:August 21, 2007 - v1
Checksum:iA85A701A8E6F8DCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR76468.1.
RefSeqiWP_004176611.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR76468; ABR76468; KPN_01033.
KEGGikpn:KPN_01033.
PATRICi20456344. VBIKlePne13394_1062.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR76468.1.
RefSeqiWP_004176611.1. NC_009648.1.

3D structure databases

ProteinModelPortaliA6T797.
SMRiA6T797.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272620.KPN_01033.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR76468; ABR76468; KPN_01033.
KEGGikpn:KPN_01033.
PATRICi20456344. VBIKlePne13394_1062.

Phylogenomic databases

eggNOGiENOG4107YAQ. Bacteria.
COG1853. LUCA.
HOGENOMiHOG000115783.
KOiK09024.
OMAiWFDRGYH.

Family and domain databases

Gene3Di2.30.110.10. 1 hit.
HAMAPiMF_00833. RutF. 1 hit.
InterProiIPR002563. Flavin_Rdtase-like_dom.
IPR019917. RutF.
IPR012349. Split_barrel_FMN-bd.
[Graphical view]
PfamiPF01613. Flavin_Reduct. 1 hit.
[Graphical view]
SMARTiSM00903. Flavin_Reduct. 1 hit.
[Graphical view]
SUPFAMiSSF50475. SSF50475. 1 hit.
TIGRFAMsiTIGR03615. RutF. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRUTF_KLEP7
AccessioniPrimary (citable) accession number: A6T797
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: August 21, 2007
Last modified: November 2, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.