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A6T6C2

- A6T6C2_KLEP7

UniProt

A6T6C2 - A6T6C2_KLEP7

Protein
Submitted name:

PTS family enzyme IIC/enzyme IIB/enzyme IIC

Gene

nagE

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.SAAS annotation

    GO - Molecular functioni

    1. kinase activity Source: UniProtKB-KW
    2. N-acetylglucosamine transmembrane transporter activity Source: InterPro
    3. protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Source: InterPro

    GO - Biological processi

    1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseSAAS annotation, Transferase

    Keywords - Biological processi

    Phosphotransferase systemSAAS annotation, Sugar transportSAAS annotation, Transport

    Enzyme and pathway databases

    BioCyciKPNE272620:GKDC-700-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PTS family enzyme IIC/enzyme IIB/enzyme IICImported
    Gene namesi
    Name:nagEImported
    ORF Names:KPN_00700Imported
    OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
    Taxonomic identifieri272620 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000000265: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. organelle inner membrane Source: InterPro
    3. plasma membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Interactioni

    Protein-protein interaction databases

    STRINGi272620.KPN_00700.

    Structurei

    3D structure databases

    ProteinModelPortaliA6T6C2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains PTS EIIA type-1 domain.SAAS annotation
    Contains PTS EIIA type-domain.SAAS annotation
    Contains PTS EIIB type-1 domain.SAAS annotation
    Contains PTS EIIB type-domain.SAAS annotation
    Contains PTS EIIC type-1 domain.SAAS annotation
    Contains PTS EIIC type-domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    eggNOGiCOG1263.
    HOGENOMiHOG000250993.
    KOiK02802.
    K02803.
    K02804.
    OMAiGMWIANS.
    OrthoDBiEOG6FFS9V.

    Family and domain databases

    Gene3Di3.30.1360.60. 1 hit.
    InterProiIPR011055. Dup_hybrid_motif.
    IPR018113. PTrfase_EIIB_Cys.
    IPR001127. PTS_EIIA_1_perm.
    IPR003352. PTS_EIIC.
    IPR013013. PTS_EIIC_1.
    IPR001996. PTS_IIB_1.
    IPR010974. PTS_IIBC_nag.
    [Graphical view]
    PfamiPF00358. PTS_EIIA_1. 1 hit.
    PF00367. PTS_EIIB. 1 hit.
    PF02378. PTS_EIIC. 1 hit.
    [Graphical view]
    SUPFAMiSSF51261. SSF51261. 1 hit.
    SSF55604. SSF55604. 1 hit.
    TIGRFAMsiTIGR00826. EIIB_glc. 1 hit.
    TIGR00830. PTBA. 1 hit.
    TIGR01998. PTS-II-BC-nag. 1 hit.
    PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
    PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
    PS51098. PTS_EIIB_TYPE_1. 1 hit.
    PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
    PS51103. PTS_EIIC_TYPE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6T6C2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNILGFFQRL GRALQLPIAV LPVAALLLRF GQPDLLNVPF IAQAGGAIFD    50
    NLALIFAIGV ASSWSKDNAG SAALAGAVGY FVMTKAMVTI NPEINMGVLA 100
    GIITGLVAGA VYNRWAGIKL PDFLSFFGGK RFVPIATGFF CLILAAIFGY 150
    VWPPVQHAIH SGGEWIVSAG ALGSGIFGFI NRLLIPTGLH QVLNTIAWFQ 200
    IGEFTNAAGA VFHGDINRFY AGDGTAGMFM SGFFPIMMFG LPGAALAMYL 250
    AAPKARRPMV GGMLLSVAIT AFLTGVTEPL EFLFMFLAPL LYLLHAVLTG 300
    ISLFIATALG IHAGFSFSAG AIDYVLMYSL PAASKNVWML LVMGVVFFFV 350
    YFLLFSAVIR MFNLKTPGRE DKAADVVTEE ANSNTEEGLT QLATSYIAAV 400
    GGTDNLKAID ACITRLRLTV GDSAKVNDAA CKRLGASGVV KLNKQTIQVI 450
    VGAKAESIGD EMKKVVTRGP VAAAAAAPAG NVATAAPAAK PQAVANAKTV 500
    ESLVSPITGD VVALEQVPDE AFASKAVGDG IAVKPTSNIV VAPAAGTVVK 550
    IFNTNHAFCL ETNNGAEIVV HMGIDTVALE GKGFKRLVEE GTDVKAGEPI 600
    LEMDLDFLNA NARSMISPVV CSNSDDYSAL VILASGKVVA GQTPLYEIKG 650
    K 651
    Length:651
    Mass (Da):68,140
    Last modified:August 21, 2007 - v1
    Checksum:i9BFF5793AE7D997F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR76143.1.
    RefSeqiYP_001334373.1. NC_009648.1.

    Genome annotation databases

    EnsemblBacteriaiABR76143; ABR76143; KPN_00700.
    GeneIDi5338357.
    KEGGikpn:KPN_00700.
    PATRICi20455646. VBIKlePne13394_0721.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000647 Genomic DNA. Translation: ABR76143.1 .
    RefSeqi YP_001334373.1. NC_009648.1.

    3D structure databases

    ProteinModelPortali A6T6C2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272620.KPN_00700.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR76143 ; ABR76143 ; KPN_00700 .
    GeneIDi 5338357.
    KEGGi kpn:KPN_00700.
    PATRICi 20455646. VBIKlePne13394_0721.

    Phylogenomic databases

    eggNOGi COG1263.
    HOGENOMi HOG000250993.
    KOi K02802.
    K02803.
    K02804.
    OMAi GMWIANS.
    OrthoDBi EOG6FFS9V.

    Enzyme and pathway databases

    BioCyci KPNE272620:GKDC-700-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1360.60. 1 hit.
    InterProi IPR011055. Dup_hybrid_motif.
    IPR018113. PTrfase_EIIB_Cys.
    IPR001127. PTS_EIIA_1_perm.
    IPR003352. PTS_EIIC.
    IPR013013. PTS_EIIC_1.
    IPR001996. PTS_IIB_1.
    IPR010974. PTS_IIBC_nag.
    [Graphical view ]
    Pfami PF00358. PTS_EIIA_1. 1 hit.
    PF00367. PTS_EIIB. 1 hit.
    PF02378. PTS_EIIC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51261. SSF51261. 1 hit.
    SSF55604. SSF55604. 1 hit.
    TIGRFAMsi TIGR00826. EIIB_glc. 1 hit.
    TIGR00830. PTBA. 1 hit.
    TIGR01998. PTS-II-BC-nag. 1 hit.
    PROSITEi PS51093. PTS_EIIA_TYPE_1. 1 hit.
    PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
    PS51098. PTS_EIIB_TYPE_1. 1 hit.
    PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
    PS51103. PTS_EIIC_TYPE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700721 / MGH 78578Imported.

    Entry informationi

    Entry nameiA6T6C2_KLEP7
    AccessioniPrimary (citable) accession number: A6T6C2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3