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Protein
Submitted name:

PTS family enzyme IIC/enzyme IIB/enzyme IIC

Gene

nagE

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei412Phosphocysteine intermediate; for EIIB activityPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processPhosphotransferase systemSAAS annotation, Sugar transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
PTS family enzyme IIC/enzyme IIB/enzyme IICImported
Gene namesi
Name:nagEImported
ORF Names:KPN_00700Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000000265 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 28HelicalSequence analysisAdd BLAST17
Transmembranei40 – 62HelicalSequence analysisAdd BLAST23
Transmembranei69 – 88HelicalSequence analysisAdd BLAST20
Transmembranei94 – 112HelicalSequence analysisAdd BLAST19
Transmembranei132 – 153HelicalSequence analysisAdd BLAST22
Transmembranei165 – 185HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21
Transmembranei232 – 252HelicalSequence analysisAdd BLAST21
Transmembranei259 – 276HelicalSequence analysisAdd BLAST18
Transmembranei282 – 306HelicalSequence analysisAdd BLAST25
Transmembranei337 – 359HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_00700.

Structurei

3D structure databases

ProteinModelPortaliA6T6C2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 371PTS EIIC type-1InterPro annotationAdd BLAST371
Domaini390 – 472PTS EIIB type-1InterPro annotationAdd BLAST83
Domaini519 – 623PTS EIIA type-1InterPro annotationAdd BLAST105

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CI1. Bacteria.
COG1263. LUCA.
COG1264. LUCA.
COG2190. LUCA.
HOGENOMiHOG000250993.
KOiK02802.
K02803.
K02804.
OMAiYNRFSHV.

Family and domain databases

CDDicd00212. PTS_IIB_glc. 1 hit.
Gene3Di3.30.1360.60. 1 hit.
InterProiView protein in InterPro
IPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR001996. PTS_IIB_1.
IPR010974. PTS_IIBC_nag.
PfamiView protein in Pfam
PF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
SUPFAMiSSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00826. EIIB_glc. 1 hit.
TIGR00830. PTBA. 1 hit.
TIGR01998. PTS-II-BC-nag. 1 hit.
PROSITEiView protein in PROSITE
PS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A6T6C2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNILGFFQRL GRALQLPIAV LPVAALLLRF GQPDLLNVPF IAQAGGAIFD
60 70 80 90 100
NLALIFAIGV ASSWSKDNAG SAALAGAVGY FVMTKAMVTI NPEINMGVLA
110 120 130 140 150
GIITGLVAGA VYNRWAGIKL PDFLSFFGGK RFVPIATGFF CLILAAIFGY
160 170 180 190 200
VWPPVQHAIH SGGEWIVSAG ALGSGIFGFI NRLLIPTGLH QVLNTIAWFQ
210 220 230 240 250
IGEFTNAAGA VFHGDINRFY AGDGTAGMFM SGFFPIMMFG LPGAALAMYL
260 270 280 290 300
AAPKARRPMV GGMLLSVAIT AFLTGVTEPL EFLFMFLAPL LYLLHAVLTG
310 320 330 340 350
ISLFIATALG IHAGFSFSAG AIDYVLMYSL PAASKNVWML LVMGVVFFFV
360 370 380 390 400
YFLLFSAVIR MFNLKTPGRE DKAADVVTEE ANSNTEEGLT QLATSYIAAV
410 420 430 440 450
GGTDNLKAID ACITRLRLTV GDSAKVNDAA CKRLGASGVV KLNKQTIQVI
460 470 480 490 500
VGAKAESIGD EMKKVVTRGP VAAAAAAPAG NVATAAPAAK PQAVANAKTV
510 520 530 540 550
ESLVSPITGD VVALEQVPDE AFASKAVGDG IAVKPTSNIV VAPAAGTVVK
560 570 580 590 600
IFNTNHAFCL ETNNGAEIVV HMGIDTVALE GKGFKRLVEE GTDVKAGEPI
610 620 630 640 650
LEMDLDFLNA NARSMISPVV CSNSDDYSAL VILASGKVVA GQTPLYEIKG

K
Length:651
Mass (Da):68,140
Last modified:August 21, 2007 - v1
Checksum:i9BFF5793AE7D997F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA. Translation: ABR76143.1.
RefSeqiWP_004147599.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR76143; ABR76143; KPN_00700.
KEGGikpn:KPN_00700.

Similar proteinsi

Entry informationi

Entry nameiA6T6C2_KLEP7
AccessioniPrimary (citable) accession number: A6T6C2
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: August 30, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported