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A6T6C2

- A6T6C2_KLEP7

UniProt

A6T6C2 - A6T6C2_KLEP7

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Protein
Submitted name:

PTS family enzyme IIC/enzyme IIB/enzyme IIC

Gene

nagE

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Catalytic activityi

Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.SAAS annotation

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
  2. N-acetylglucosamine transmembrane transporter activity Source: InterPro
  3. protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Source: InterPro

GO - Biological processi

  1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

Phosphotransferase systemSAAS annotation, Sugar transportSAAS annotation, Transport

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-700-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
PTS family enzyme IIC/enzyme IIB/enzyme IICImported
Gene namesi
Name:nagEImported
ORF Names:KPN_00700Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. organelle inner membrane Source: InterPro
  3. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_00700.

Structurei

3D structure databases

ProteinModelPortaliA6T6C2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains PTS EIIA type-1 domain.SAAS annotation
Contains PTS EIIA type-domain.SAAS annotation
Contains PTS EIIB type-1 domain.SAAS annotation
Contains PTS EIIB type-domain.SAAS annotation
Contains PTS EIIC type-1 domain.SAAS annotation
Contains PTS EIIC type-domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiCOG1263.
HOGENOMiHOG000250993.
KOiK02802.
K02803.
K02804.
OMAiGMWIANS.
OrthoDBiEOG6FFS9V.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR001996. PTS_IIB_1.
IPR010974. PTS_IIBC_nag.
[Graphical view]
PfamiPF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00826. EIIB_glc. 1 hit.
TIGR00830. PTBA. 1 hit.
TIGR01998. PTS-II-BC-nag. 1 hit.
PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6T6C2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNILGFFQRL GRALQLPIAV LPVAALLLRF GQPDLLNVPF IAQAGGAIFD
60 70 80 90 100
NLALIFAIGV ASSWSKDNAG SAALAGAVGY FVMTKAMVTI NPEINMGVLA
110 120 130 140 150
GIITGLVAGA VYNRWAGIKL PDFLSFFGGK RFVPIATGFF CLILAAIFGY
160 170 180 190 200
VWPPVQHAIH SGGEWIVSAG ALGSGIFGFI NRLLIPTGLH QVLNTIAWFQ
210 220 230 240 250
IGEFTNAAGA VFHGDINRFY AGDGTAGMFM SGFFPIMMFG LPGAALAMYL
260 270 280 290 300
AAPKARRPMV GGMLLSVAIT AFLTGVTEPL EFLFMFLAPL LYLLHAVLTG
310 320 330 340 350
ISLFIATALG IHAGFSFSAG AIDYVLMYSL PAASKNVWML LVMGVVFFFV
360 370 380 390 400
YFLLFSAVIR MFNLKTPGRE DKAADVVTEE ANSNTEEGLT QLATSYIAAV
410 420 430 440 450
GGTDNLKAID ACITRLRLTV GDSAKVNDAA CKRLGASGVV KLNKQTIQVI
460 470 480 490 500
VGAKAESIGD EMKKVVTRGP VAAAAAAPAG NVATAAPAAK PQAVANAKTV
510 520 530 540 550
ESLVSPITGD VVALEQVPDE AFASKAVGDG IAVKPTSNIV VAPAAGTVVK
560 570 580 590 600
IFNTNHAFCL ETNNGAEIVV HMGIDTVALE GKGFKRLVEE GTDVKAGEPI
610 620 630 640 650
LEMDLDFLNA NARSMISPVV CSNSDDYSAL VILASGKVVA GQTPLYEIKG

K
Length:651
Mass (Da):68,140
Last modified:August 21, 2007 - v1
Checksum:i9BFF5793AE7D997F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR76143.1.
RefSeqiYP_001334373.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR76143; ABR76143; KPN_00700.
GeneIDi5338357.
KEGGikpn:KPN_00700.
PATRICi20455646. VBIKlePne13394_0721.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR76143.1 .
RefSeqi YP_001334373.1. NC_009648.1.

3D structure databases

ProteinModelPortali A6T6C2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272620.KPN_00700.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR76143 ; ABR76143 ; KPN_00700 .
GeneIDi 5338357.
KEGGi kpn:KPN_00700.
PATRICi 20455646. VBIKlePne13394_0721.

Phylogenomic databases

eggNOGi COG1263.
HOGENOMi HOG000250993.
KOi K02802.
K02803.
K02804.
OMAi GMWIANS.
OrthoDBi EOG6FFS9V.

Enzyme and pathway databases

BioCyci KPNE272620:GKDC-700-MONOMER.

Family and domain databases

Gene3Di 3.30.1360.60. 1 hit.
InterProi IPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR001996. PTS_IIB_1.
IPR010974. PTS_IIBC_nag.
[Graphical view ]
Pfami PF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view ]
SUPFAMi SSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsi TIGR00826. EIIB_glc. 1 hit.
TIGR00830. PTBA. 1 hit.
TIGR01998. PTS-II-BC-nag. 1 hit.
PROSITEi PS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578Imported.

Entry informationi

Entry nameiA6T6C2_KLEP7
AccessioniPrimary (citable) accession number: A6T6C2
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3