ID   A6T661_KLEP7            Unreviewed;       412 AA.
AC   A6T661;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Cytosine deaminase and related metal-dependent hydrolases {ECO:0000313|EMBL:ABR76082.1};
GN   ORFNames=KPN_00632 {ECO:0000313|EMBL:ABR76082.1};
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR76082.1, ECO:0000313|Proteomes:UP000000265};
RN   [1] {ECO:0000313|EMBL:ABR76082.1, ECO:0000313|Proteomes:UP000000265}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [2] {ECO:0000313|EMBL:ABR76082.1, ECO:0000313|Proteomes:UP000000265}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000647; ABR76082.1; -; Genomic_DNA.
DR   RefSeq; WP_002894156.1; NC_009648.1.
DR   AlphaFoldDB; A6T661; -.
DR   SMR; A6T661; -.
DR   STRING; 272620.KPN_00632; -.
DR   PaxDb; 272620-KPN_00632; -.
DR   EnsemblBacteria; ABR76082; ABR76082; KPN_00632.
DR   KEGG; kpn:KPN_00632; -.
DR   HOGENOM; CLU_031758_0_1_6; -.
DR   BioCyc; MetaCyc:MONOMER-19104; -.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   CDD; cd01293; Bact_CD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR013108; Amidohydro_3.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR32027; CYTOSINE DEAMINASE; 1.
DR   PANTHER; PTHR32027:SF0; CYTOSINE DEAMINASE; 1.
DR   Pfam; PF07969; Amidohydro_3; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABR76082.1}.
FT   DOMAIN          40..400
FT                   /note="Amidohydrolase 3"
FT                   /evidence="ECO:0000259|Pfam:PF07969"
SQ   SEQUENCE   412 AA;  45893 MW;  86257A0255C92463 CRC64;
     MKIINARLRR QEALFTLDLQ DGIIHRITAQ AAMQTADAGA IDAQGRLAIP PFVEPHIHLD
     ATLTAGEPEW NRSGTLFEGI TRWSQRKASI TPEDTRQRAL KTIGMLRDFG VQHVRTHVDV
     TDPSLAALQA LLAVKQEAAD LIDLQIVAFP QEGIESYPNG RELMTRAIEM GADVVGGIPH
     YENTRDKGVS SVMFLMDLAQ RYGRLVDVHC DEIDDPQSRF LEVLAEEARV RGMGAQVTAS
     HTCAMGSYDN AYCSKLFRLL KASGINFISC PTESIHLQGR FDSWPKRRGV TRVAELDRAG
     INVCFAQDSI QDPWYPLGNG NILRILDAGL HICHMLGYDD LQRCLDFVTD NSARALCLGD
     NYGLAEGRPA NLLILDAEND YEAVRRQARV LTSIRHGKVI LQREVEHIRY PA
//