Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:KPN78578_00450
ORF Names:KPN_00046
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000000265 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120671 – 282Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST282

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_00046

Structurei

3D structure databases

ProteinModelPortaliA6T4I5
SMRiA6T4I5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

A6T4I5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTYLIGDVH GCYDELIALL AQVEFDPRRD TLWLTGDLVA RGPGSLEVLR
60 70 80 90 100
YVKSLGDSVR LVLGNHDLHL LAVFAGISRN KPKDRLKPLL EAPDADELLN
110 120 130 140 150
WLRRQPLLQV DEEKKLVMAH AGITPQWDLE TAQQCARDVE AVLSSDSYPF
160 170 180 190 200
FLDAMYGDMP NHWSNELSGL ARLRFISNAF TRMRYCFPNG QLDMYSKEAP
210 220 230 240 250
EDAPAPLKPW FAIPGPVSNA YSIAFGHWAS LEGRGTPEGI YALDTGCCWG
260 270 280
GELTCLRWED KQYFTQPSNR QKSLDEGEAV AS
Length:282
Mass (Da):31,608
Last modified:August 21, 2007 - v1
Checksum:i6338617FE9FC7C21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000647 Genomic DNA Translation: ABR75506.1
RefSeqiWP_002888321.1, NC_009648.1

Genome annotation databases

EnsemblBacteriaiABR75506; ABR75506; KPN_00046
KEGGikpn:KPN_00046

Similar proteinsi

Entry informationi

Entry nameiAPAH_KLEP7
AccessioniPrimary (citable) accession number: A6T4I5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health