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A6T1Y2 (A6T1Y2_JANMA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401

Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401
Gene names
Name:msrA2 HAMAP MF_01401 EMBL ABR89701.1
Ordered Locus Names:mma_2839
OrganismJanthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) [Complete proteome] [HAMAP]
Taxonomic identifier375286 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeJanthinobacterium

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site121 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
A6T1Y2 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 3168D7544AB74420

FASTA17920,271
        10         20         30         40         50         60 
MAMEIATLGG GCFWCTEAVF QQLKGIKAVE SGYTGGHVEN PVYEQICEGT TGHAEVVRLT 

        70         80         90        100        110        120 
YDPEIVSFRE ILEIFFTIHD PTTLNRQGND VGTQYRSVIY YHSPEQQDTA KHVISEMANV 

       130        140        150        160        170 
WDAPIVTELS PAETYYKAES YHQNYFRMNP MQGYCAFIVA PKVSKFRKTF SDKISGDMI 

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References

[1]"Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria."
Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D., Drancourt M.
PLoS Genet. 3:1454-1463(2007) [PubMed: 17722982] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000269 Genomic DNA. Translation: ABR89701.1.
RefSeqYP_001354529.1. NC_009659.1.

3D structure databases

ProteinModelPortalA6T1Y2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6T1Y2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5349835.
GenomeReviewsGene locus mma_2839 in contig CP000269_GR.
KEGGmms:mma_2839.
PATRIC22158195. VBIJanSp106498_2860.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMAIDTEVGY.
ProtClustDBCLSK967374.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6T1Y2_JANMA
AccessionPrimary (citable) accession number: A6T1Y2
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)