SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A6SW90

- ASSY_JANMA

UniProt

A6SW90 - ASSY_JANMA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Argininosuccinate synthase
Gene
argG, mma_0847
Organism
Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431ATP By similarity
Binding sitei99 – 991Citrulline By similarity
Binding sitei129 – 1291ATP; via amide nitrogen By similarity
Binding sitei131 – 1311Aspartate By similarity
Binding sitei131 – 1311ATP By similarity
Binding sitei135 – 1351Aspartate By similarity
Binding sitei135 – 1351Citrulline By similarity
Binding sitei136 – 1361Aspartate By similarity
Binding sitei136 – 1361ATP By similarity
Binding sitei139 – 1391Citrulline By similarity
Binding sitei192 – 1921Citrulline By similarity
Binding sitei194 – 1941ATP By similarity
Binding sitei201 – 2011Citrulline By similarity
Binding sitei203 – 2031Citrulline By similarity
Binding sitei280 – 2801Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi17 – 259ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciJSP375286:GJ8U-864-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:mma_0847
OrganismiJanthinobacterium sp. (strain Marseille) (Minibacterium massiliensis)
Taxonomic identifieri375286 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeJanthinobacterium
ProteomesiUP000006388: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 447447Argininosuccinate synthaseUniRule annotation
PRO_1000129755Add
BLAST

Proteomic databases

PRIDEiA6SW90.

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi375286.mma_0847.

Structurei

3D structure databases

ProteinModelPortaliA6SW90.
SMRiA6SW90. Positions 2-440.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230094.
KOiK01940.
OMAiRQEMSEF.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di1.10.287.400. 1 hit.
3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00581. Arg_succ_synth_type2.
InterProiIPR023437. Arg_succ_synth_type2_subfam.
IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR024074. AS_cat/multimer_dom_body.
IPR024073. AS_multimer_C_tail.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6SW90-1 [UniParc]FASTAAdd to Basket

« Hide

MSNILQSVPV NQKVGIAFSG GLDTSAALHW MRQKGAIPYA YTANLGQPDE    50
TDYNAIPEKA KAYGAELARL IDCREQLVAE GIAALQSGAF HISTAGVTYF 100
NTTPLGRAVT GTMLVAAMKE DNVDIWGDGS TFKGNDIERF YRYGLLMNPA 150
LRIYKPWLDD TFIQELGGRK EMSEFLIKSG FDYKMSVEKA YSTDSNILGA 200
THEAKDLEEL SSGMKIVQPI MGVAFWRDDV EVKREEVTVR FEEGRPVALN 250
GVVYSDLVEL MLEANRIGGR HGLGMSDQIE NRIIEAKSRG IYEAPGLALL 300
FIAYERLVTG IHNEDTIEQY RESGRRLGRL LYQGRWFDPQ AIMLREAAQR 350
WVARAITGEV TIELRRGNDY SILNTVSANL TYAPERLSME KVEDAPFSPA 400
DRIGQLTMRN LDITDTRQKL GIYNDVGLLT GNTSVALPRI GKDSDKK 447
Length:447
Mass (Da):49,798
Last modified:August 21, 2007 - v1
Checksum:i428A17A624C35C3D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000269 Genomic DNA. Translation: ABR88363.1.
RefSeqiWP_012078711.1. NC_009659.1.
YP_001352537.1. NC_009659.1.

Genome annotation databases

EnsemblBacteriaiABR88363; ABR88363; mma_0847.
GeneIDi5350885.
KEGGimms:mma_0847.
PATRICi22154171. VBIJanSp106498_0874.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000269 Genomic DNA. Translation: ABR88363.1 .
RefSeqi WP_012078711.1. NC_009659.1.
YP_001352537.1. NC_009659.1.

3D structure databases

ProteinModelPortali A6SW90.
SMRi A6SW90. Positions 2-440.
ModBasei Search...

Protein-protein interaction databases

STRINGi 375286.mma_0847.

Proteomic databases

PRIDEi A6SW90.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR88363 ; ABR88363 ; mma_0847 .
GeneIDi 5350885.
KEGGi mms:mma_0847.
PATRICi 22154171. VBIJanSp106498_0874.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230094.
KOi K01940.
OMAi RQEMSEF.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci JSP375286:GJ8U-864-MONOMER.

Family and domain databases

Gene3Di 1.10.287.400. 1 hit.
3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00581. Arg_succ_synth_type2.
InterProi IPR023437. Arg_succ_synth_type2_subfam.
IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR024074. AS_cat/multimer_dom_body.
IPR024073. AS_multimer_C_tail.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria."
    Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D., Drancourt M.
    PLoS Genet. 3:1454-1463(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Marseille.

Entry informationi

Entry nameiASSY_JANMA
AccessioniPrimary (citable) accession number: A6SW90
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: August 21, 2007
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi