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A6SVJ9

- PYRF_JANMA

UniProt

A6SVJ9 - PYRF_JANMA

Protein

Orotidine 5'-phosphate decarboxylase

Gene

pyrF

Organism
Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei95 – 951Proton donorUniRule annotation

    GO - Molecular functioni

    1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Pyrimidine biosynthesis

    Enzyme and pathway databases

    BioCyciJSP375286:GJ8U-622-MONOMER.
    UniPathwayiUPA00070; UER00120.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Orotidine 5'-phosphate decarboxylaseUniRule annotation (EC:4.1.1.23UniRule annotation)
    Alternative name(s):
    OMP decarboxylaseUniRule annotation
    Short name:
    OMPDCaseUniRule annotation
    Short name:
    OMPdecaseUniRule annotation
    Gene namesi
    Name:pyrFUniRule annotation
    Ordered Locus Names:mma_0606
    OrganismiJanthinobacterium sp. (strain Marseille) (Minibacterium massiliensis)
    Taxonomic identifieri375286 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeJanthinobacterium
    ProteomesiUP000006388: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 271271Orotidine 5'-phosphate decarboxylasePRO_1000066474Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi375286.mma_0606.

    Structurei

    3D structure databases

    ProteinModelPortaliA6SVJ9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the OMP decarboxylase family. Type 2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0284.
    HOGENOMiHOG000245747.
    KOiK01591.
    OMAiCRTSNAG.
    OrthoDBiEOG6DZF33.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_01215. OMPdecase_type2.
    InterProiIPR013785. Aldolase_TIM.
    IPR018089. OMPdecase_AS.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00215. OMPdecase. 1 hit.
    [Graphical view]
    SMARTiSM00934. OMPdecase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.
    PROSITEiPS00156. OMPDECASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6SVJ9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTFIEKLSAV WQSQKTQLCI GLDPDLAKFP AHLKGKPDAI LTFCKEIIDA    50
    TADTACAFKP QIAYFAALRA EDQLEAICSY LRERYPHIPI VLDAKRGDIG 100
    ATAEQYAREA FERYGADAVT VNPYMGFDSV QPYLERPDRG VIVLCRTSNA 150
    GGSDLQFLNV DGKPLYQHVA QLVADKWNTN GQCALVVGAT FPNELAQVRA 200
    LVGDMPLLIP GIGAQGGDIK ATVEAGRTAN GTGMMINSSR AILYAKADET 250
    FAQAARQVAL ETRDAINRYI A 271
    Length:271
    Mass (Da):29,446
    Last modified:August 21, 2007 - v1
    Checksum:i41BA3BE4762755EE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000269 Genomic DNA. Translation: ABR88485.1.
    RefSeqiWP_012078470.1. NC_009659.1.
    YP_001352296.1. NC_009659.1.

    Genome annotation databases

    EnsemblBacteriaiABR88485; ABR88485; mma_0606.
    GeneIDi5353157.
    KEGGimms:mma_0606.
    PATRICi22153673. VBIJanSp106498_0626.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000269 Genomic DNA. Translation: ABR88485.1 .
    RefSeqi WP_012078470.1. NC_009659.1.
    YP_001352296.1. NC_009659.1.

    3D structure databases

    ProteinModelPortali A6SVJ9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 375286.mma_0606.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR88485 ; ABR88485 ; mma_0606 .
    GeneIDi 5353157.
    KEGGi mms:mma_0606.
    PATRICi 22153673. VBIJanSp106498_0626.

    Phylogenomic databases

    eggNOGi COG0284.
    HOGENOMi HOG000245747.
    KOi K01591.
    OMAi CRTSNAG.
    OrthoDBi EOG6DZF33.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00120 .
    BioCyci JSP375286:GJ8U-622-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_01215. OMPdecase_type2.
    InterProi IPR013785. Aldolase_TIM.
    IPR018089. OMPdecase_AS.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00215. OMPdecase. 1 hit.
    [Graphical view ]
    SMARTi SM00934. OMPdecase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
    PROSITEi PS00156. OMPDECASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria."
      Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D., Drancourt M.
      PLoS Genet. 3:1454-1463(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Marseille.

    Entry informationi

    Entry nameiPYRF_JANMA
    AccessioniPrimary (citable) accession number: A6SVJ9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3