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A6SU56 (SYR_JANMA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:mma_0113
OrganismJanthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) [Complete proteome] [HAMAP]
Taxonomic identifier375286 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeJanthinobacterium

Protein attributes

Sequence length577 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 577577Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018045

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A6SU56 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: E2CD889C7E74CE38

FASTA57763,513
        10         20         30         40         50         60 
MLAAQKQRLT ELFQAAVAPL VASTDLQPTI TLERPRDPSH GDVACNLAMQ IAKPLKKNPR 

        70         80         90        100        110        120 
EVAQALAAAL LDNPANRDLI EAADIAGPGF INLRLTAASR QAVVKTVLQQ GAEFGKSNLG 

       130        140        150        160        170        180 
NDKKVIIEFV SANPTGPLHV GHGRQGALGD AMSSLFQAQG YDVTREFYYN DAGVQIATLA 

       190        200        210        220        230        240 
TSVQARGKGL KPGVEGWPES AYNGDYIQDI ANDFLAKKTV SASNGEPVTA SGDINDIESI 

       250        260        270        280        290        300 
RQFSVTYLRR EQDLDLQAFG VKFDNYYLES SLYADGKVEK TVDALIKADK TYELDGALWL 

       310        320        330        340        350        360 
RTTDYRDDKD RVMKKSDGTY TYFVPDVAYH TVKWQRGFTQ AINVQGSDHH GTIARVRAGL 

       370        380        390        400        410        420 
QALDIGIPQG YPDYVLHKMV TVMRNGEEVK ISKRAGSYVT LRDLIEWSNG EVVDGEVRDL 

       430        440        450        460        470        480 
TRGRDAVRFF LISRKADTEF VFDVDIALTQ GDENPVYYVQ YAHARICSVL AQWTDGDEAS 

       490        500        510        520        530        540 
LDKVDLSPLT AARETALLAK LAEYPETLQK ALEELGPHQV AFYLRDLAGE LHSYYNAERV 

       550        560        570 
LVDDEALKMA RIALMSATRQ VLRNGLALIG VSAPARM 

« Hide

References

[1]"Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria."
Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D., Drancourt M.
PLoS Genet. 3:1454-1463(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Marseille.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000269 Genomic DNA. Translation: ABR88723.1.
RefSeqYP_001351803.1. NC_009659.1.

3D structure databases

ProteinModelPortalA6SU56.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING375286.mma_0113.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR88723; ABR88723; mma_0113.
GeneID5352384.
KEGGmms:mma_0113.
PATRIC22152625. VBIJanSp106498_0118.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycJSP375286:GJ8U-113-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_JANMA
AccessionPrimary (citable) accession number: A6SU56
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries