A6SMB5 (A6SMB5_BOTFB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Mannose-6-phosphate isomerase RuleBase RU000611
EC=5.3.1.8 RuleBase RU000611

Gene names

ORF Names:

BC1G_13823 EMBL EDN20026.1

Organism

Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) [Complete proteome]

Taxonomic identifier

332648 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Leotiomycetes › Helotiales › Sclerotiniaceae › Botryotinia

Protein attributes

Sequence length	453 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannose 6-phosphate = D-fructose 6-phosphate. RuleBase RU000611
Cofactor	Binds 1 zinc ion per subunit By similarity. RuleBase RU000611
Pathway	Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2. RuleBase RU004248
Sequence similarities	Belongs to the mannose-6-phosphate isomerase type 1 family. RuleBase RU004189

Ontologies

Keywords
Ligand	Zinc RuleBase RU000611
Molecular function	Isomerase RuleBase RU000611
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6SMB5 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 3C26E890FAF61117	FASTA	453	49,504
	10 20 30 40 50 60 MQVPLIRLQC GVNSYDWGKV GSDSAAAKFA AATPADDFSI QEEKPYAELW MGTHPSNPSK 70 80 90 100 110 120 DLTTKRTLLD LVQDNQALLS KDVSDKFGEK LPFLFKVLSI GKALSIQAHP NKKLAEQLHQ 130 140 150 160 170 180 KDSKNYPDDN HKPEMTIAIT PFDGLCGFRP LAEISHFLST IPSLRKLVGE SEVEEFQSAI 190 200 210 220 230 240 KGQETSEASE DEKKNKKALQ KVFTALMNAE KEDVENASKE LVASAEEEGD NFAGGGGPSN 250 260 270 280 290 300 EGKELADLVI RLNKQFPGDV GLFVQFFLNY VKLEVGEAMF LKADDIHAYL SGDIIECMAA 310 320 330 340 350 360 SDNVVRAGFT PKFKDVDTLT SMLTYSYAPI SEQKMEPVDY PYATLNATAY SSGSSATLYD 370 380 390 400 410 420 PPIAEFSVVK TDLNKKGAKA TFEQIAGPSI FICTTGNGKI SVGPKVEEVK PGYVYFVGAT 430 440 450 AEVVLEAEDE EFTTFKAFCE LQGKEDADGK EKL

References

[1]

"Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea." Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A., Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E., Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M., Quevillon E. , Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P., Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I., Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P., Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C., Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C., Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E., Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N., Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E., Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O., Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M. PLoS Genet. 7:E1002230-E1002230(2011) [PubMed: 21876677] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B05.10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH476970 Genomic DNA. Translation: EDN20026.1.
RefSeq	XP_001547579.1. XM_001547529.1.
3D structure databases
ProteinModelPortal	A6SMB5.
ModBase	Search...
Protein-protein interaction databases
STRING	A6SMB5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5428048.
KEGG	bfu:BC1G_13823.
Phylogenomic databases
OMA	GTHPSVP.
OrthoDB	EOG4TF3V5.
Family and domain databases
InterPro	IPR011051. Cupin_RmlC_type. IPR001250. Man6P_Isoase-1. IPR016305. Mannose-6-P_Isomerase. IPR018050. Pmannose_isomerase-type1_CS. IPR014710. RmlC-like_jellyroll. [Graphical view]
Gene3D	G3DSA:2.60.120.10. RmlC-like_jellyroll. 3 hits.
KO	K01809.
PANTHER	PTHR10309. PTHR10309. 1 hit.
Pfam	PF01238. PMI_typeI. 1 hit. [Graphical view]
PIRSF	PIRSF001480. Mannose-6-phosphate_isomerase. 1 hit.
PRINTS	PR00714. MAN6PISMRASE.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
TIGRFAMs	TIGR00218. ManA. 1 hit.
PROSITE	PS00965. PMI_I_1. 1 hit. PS00966. PMI_I_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6SMB5_BOTFB

Accession

Primary (citable) accession number: A6SMB5

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)