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A6SL49 (DAPB_BOTFB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dipeptidyl-aminopeptidase B

Short name=DPAP B
EC=3.4.14.5
Gene names
Name:dapB
ORF Names:BC1G_13641
OrganismBotryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
Taxonomic identifier332648 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaLeotiomycetesHelotialesSclerotiniaceaeBotryotinia

Protein attributes

Sequence length921 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activity

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein By similarity. Note: Lysosome-like vacuoles By similarity.

Sequence similarities

Belongs to the peptidase S9B family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 921921Probable dipeptidyl-aminopeptidase B
PRO_0000412140

Regions

Topological domain1 – 109109Cytoplasmic Potential
Transmembrane110 – 13021Helical; Signal-anchor for type II membrane protein; Potential
Topological domain131 – 921791Vacuolar Potential
Compositional bias79 – 835Poly-Glu

Sites

Active site7681Charge relay system By similarity
Active site8451Charge relay system By similarity
Active site8781Charge relay system By similarity

Amino acid modifications

Glycosylation3621N-linked (GlcNAc...) Potential
Glycosylation8221N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A6SL49 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 8839279EA0C373D8

FASTA921103,088
        10         20         30         40         50         60 
MAGHPEENAQ LLSTEQESMS RNSSDSVAST ASTTSLVFDR IGERVAANGS EKPTMVTPKF 

        70         80         90        100        110        120 
PPRGERAYAD DEHTQIHLEE EEEKDYDMED GAFLTNGATN KSVDKKLRRL IWIIGGVFIG 

       130        140        150        160        170        180 
AWVLALFIFL GKQAYKHSSE SPHDPQATSS RGSGKKVTMD QVMGGQWRAT KHSISWIEGA 

       190        200        210        220        230        240 
NGEDGLLLEQ GSVGKDYLIV EDVRTQSPSA VGTLDTMTLM KNGYFEVAGR SLTPSKVYPS 

       250        260        270        280        290        300 
KDLKKVLVAT DVQSNWRHSF YAKYWIFDVE TQTAEPLDPV DLDGRVQLAS WSPKSDAIVF 

       310        320        330        340        350        360 
TRDNNMYLRK LASPTVVQIT VDGGPEFFYG VPDWVYEEEV FAGASATWWD DSGKYIAFLR 

       370        380        390        400        410        420 
TNESEVPEYP VQYFVSRPSG KDPLPGEENY PEVREIKYPK AGAPNPTVDL LFYDISKAEV 

       430        440        450        460        470        480 
FEVKIAGGFE PKDLLITEVV WAGSTGKALI RETNRESDVL RVVLVDVVAR EGKTVRFTDI 

       490        500        510        520        530        540 
AKLDGGWFEV SEDTRYIPAD PANGRPHDGY IDTIIHENYD HLGYFTPMDN SEPILLTSGD 

       550        560        570        580        590        600 
WEVVKAPSAV DLKNNIVYFI STKESPITRQ LYSVKLDGTD LKAITDTSTE GYYGASFSKG 

       610        620        630        640        650        660 
AGYVLLNYNG PNIPWQKVIS TPSNDNQYTH IIEENKGLAD MAKKHELPIL IYQTVTVDGF 

       670        680        690        700        710        720 
ELQVVERRPP HFNPKKKYPV LFYLYGGPGS QTVSKSFGVD FQSYIASNLG YIVVTVDGRG 

       730        740        750        760        770        780 
TGFIGRKART IIRGNIGHYE ARDQIETAKI WASKKYVDES RMAIWGWSYG GFMTLKTLEQ 

       790        800        810        820        830        840 
DAGETFSYGM AVAPVTDWRF YDSIYTERYM HTPQHNPGGY DNTSISDVKS LAKNVRFLVM 

       850        860        870        880        890        900 
HGVADDNVHM QNTLTLLDKL DLAGVENYDV HVFPDSDHSI YFHNANRIVY DKLNNWLINA 

       910        920 
FNGEWLRTAN AVPLEIDAAK V 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH476961 Genomic DNA. Translation: EDN19610.1.
RefSeqXP_001547950.1. XM_001547900.1.

3D structure databases

ProteinModelPortalA6SL49.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING332648.A6SL49.

Protein family/group databases

MEROPSS09.006.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5428447.
KEGGbfu:BC1G_13641.

Phylogenomic databases

eggNOGCOG1506.
KOK01282.
OMAETKFWYQ.

Family and domain databases

InterProIPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPB_BOTFB
AccessionPrimary (citable) accession number: A6SL49
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: August 21, 2007
Last modified: February 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries