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Protein
Submitted name:

Uncharacterized protein

Gene

HCAG_06440

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:HCAG_06440Imported
OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
Taxonomic identifieri339724 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeHistoplasma
Proteomesi
  • UP000009297 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:HCAG_06440

Subcellular locationi

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi339724.XP_001538835.1

Structurei

3D structure databases

ProteinModelPortaliA6R7Z9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 129SH3InterPro annotationAdd BLAST60
Domaini771 – 904N-terminal Ras-GEFInterPro annotationAdd BLAST134
Domaini940 – 1176Ras-GEFInterPro annotationAdd BLAST237

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3417 Eukaryota
ENOG410XR96 LUCA
KOiK03099
OrthoDBiEOG092C0VYU

Family and domain databases

CDDicd00155 RasGEF, 1 hit
cd06224 REM, 1 hit
Gene3Di1.10.840.10, 2 hits
InterProiView protein in InterPro
IPR000651 Ras-like_Gua-exchang_fac_N
IPR019804 Ras_G-nucl-exch_fac_CS
IPR023578 Ras_GEF_dom_sf
IPR001895 RASGEF_cat_dom
IPR036964 RASGEF_cat_dom_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00617 RasGEF, 1 hit
PF00618 RasGEF_N, 1 hit
PF00018 SH3_1, 1 hit
PRINTSiPR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00147 RasGEF, 1 hit
SM00229 RasGEFN, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF48366 SSF48366, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS00720 RASGEF, 1 hit
PS50009 RASGEF_CAT, 1 hit
PS50212 RASGEF_NTER, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

A6R7Z9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSSRSAVPL TVNSKSVLNA KPGTFAAAFH YTEDEALSSN DNSQYHSTNN
60 70 80 90 100
HSYHADMARH HGNDGYVESP PALYVRALYN YTADDHTSLS FRQGDIIQVL
110 120 130 140 150
NQLDTGWWDG VMGDVRGWFP SNYCAVVTDP DSIGLGGGHF GHESGDISAE
160 170 180 190 200
SGADDYDDDD DLDSEGNSKD ERSILPTEGT RGSEHEEAAF WIPQATADGR
210 220 230 240 250
LFYFNTLTGR STAELPLESP MSATETGPRD RTNIFVPEQT RPPPELMVGG
260 270 280 290 300
IDRDEDDYDG SGSEAEGESL IRSSHDSESR RRRSFISDGV SPATSLDSIN
310 320 330 340 350
ASPIVISYSE SKHTHQSPPS SSGQLPSNSG VLSSAANAQP AQNERLSSQS
360 370 380 390 400
ISSTIPRLFL DDGSSTPLTW NKLVGNMRQA IDAYRRAIME GHREQYVRRA
410 420 430 440 450
EDISDHLRML LAAGSDTTDN HSGNPSIIST NKALYPHFRD MMSKFSKLVL
460 470 480 490 500
SSHIAAADWR GPDSDAKCLQ EAEGVLHGVY GYVEVAKQQR GDDISRLVPG
510 520 530 540 550
FVQGSSSGGH WQNNNVGIRN PTTFLDYENQ DSGLEPTVVL NSNIVYRIEN
560 570 580 590 600
LKDMLAASTR RLEENLSLSE KTITPRIHLA IADTVCAACS RVVECFQPWM
610 620 630 640 650
SLVESIDLSP LERGSQNPQL VDYSLQKQRA YDGIADLVLS CQAVSAPLGD
660 670 680 690 700
EWAEMRGDTL ETRLAGVRSV SRQLQNYVAQ IGFSLTLLLE QAPSEAPPAR
710 720 730 740 750
DIGGASLSKV PSGSIGMPSA YPPADRQPVK SRANIDKAQR FFGDTIPTEP
760 770 780 790 800
AMQWYLNIDH ESEVFYDNKG EVPTLKCGTL AGLVEHLTRH DKLDTSFNST
810 820 830 840 850
FLLTYRSFTT ASELFEMLVH RFTLQPPYGL DKTDLQTWTE QKQIPIRIRV
860 870 880 890 900
VNIMKNWFEN YWMEPNDDAN MRLLQRVYAF VKDSIGKAKT PGSQQLLSLI
910 920 930 940 950
DQRMRGQDTS AKRLVPTISG NAPPPILPKN LKKLKFLDID PMEFARQLTI
960 970 980 990 1000
IESRLYARIK PTECLNKTWQ KKLVPDEPDP AANVKALILH SNQLTNWVAE
1010 1020 1030 1040 1050
MILHQQDVKR RVVVIKHFVL IAERCRAMNN YSTLTSIISA LGTAPVHRLN
1060 1070 1080 1090 1100
RTWAQVSARI LAVLENMRRL MASTKNFGEY REALHLANPP CIPFFGVYLT
1110 1120 1130 1140 1150
DLTFIEDGIP SLTQSHLINF NKRAKTAEVI RDIQQYQNAP YPFHPVPELQ
1160 1170 1180 1190 1200
DYVLSNMQAA GDVHEMYDRS LEVEPRERED EKIARYGQMN DASVFALMIS

T
Length:1,201
Mass (Da):133,821
Last modified:August 21, 2007 - v1
Checksum:i42EA3CCDC5E6E530
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476660 Genomic DNA Translation: EDN09273.1
RefSeqiXP_001538835.1, XM_001538785.1

Genome annotation databases

EnsemblFungiiEDN09273; EDN09273; HCAG_06440
GeneIDi5445139
KEGGiaje:HCAG_06440

Similar proteinsi

Entry informationi

Entry nameiA6R7Z9_AJECN
AccessioniPrimary (citable) accession number: A6R7Z9
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 25, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health