A6R7Z9 (A6R7Z9_AJECN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL EDN09273.1

Gene names

ORF Names:

HCAG_06440 EMBL EDN09273.1

Organism

Ajellomyces capsulata (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum) [Complete proteome] EMBL EDN09273.1

Taxonomic identifier

339724 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Onygenales › Ajellomycetaceae › Ajellomyces › Ajellomyces capsulatus

Protein attributes

Sequence length	1201 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 N-terminal Ras-GEF domain. SAAS SAAS000651 Contains 1 Ras-GEF domain. SAAS SAAS000651 Contains 1 SH3 domain. RuleBase RU003338

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338
Molecular function	Guanine-nucleotide releasing factor SAAS SAAS000651
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6R7Z9 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 42EA3CCDC5E6E530	FASTA	1,201	133,821
	10 20 30 40 50 60 MYSSRSAVPL TVNSKSVLNA KPGTFAAAFH YTEDEALSSN DNSQYHSTNN HSYHADMARH 70 80 90 100 110 120 HGNDGYVESP PALYVRALYN YTADDHTSLS FRQGDIIQVL NQLDTGWWDG VMGDVRGWFP 130 140 150 160 170 180 SNYCAVVTDP DSIGLGGGHF GHESGDISAE SGADDYDDDD DLDSEGNSKD ERSILPTEGT 190 200 210 220 230 240 RGSEHEEAAF WIPQATADGR LFYFNTLTGR STAELPLESP MSATETGPRD RTNIFVPEQT 250 260 270 280 290 300 RPPPELMVGG IDRDEDDYDG SGSEAEGESL IRSSHDSESR RRRSFISDGV SPATSLDSIN 310 320 330 340 350 360 ASPIVISYSE SKHTHQSPPS SSGQLPSNSG VLSSAANAQP AQNERLSSQS ISSTIPRLFL 370 380 390 400 410 420 DDGSSTPLTW NKLVGNMRQA IDAYRRAIME GHREQYVRRA EDISDHLRML LAAGSDTTDN 430 440 450 460 470 480 HSGNPSIIST NKALYPHFRD MMSKFSKLVL SSHIAAADWR GPDSDAKCLQ EAEGVLHGVY 490 500 510 520 530 540 GYVEVAKQQR GDDISRLVPG FVQGSSSGGH WQNNNVGIRN PTTFLDYENQ DSGLEPTVVL 550 560 570 580 590 600 NSNIVYRIEN LKDMLAASTR RLEENLSLSE KTITPRIHLA IADTVCAACS RVVECFQPWM 610 620 630 640 650 660 SLVESIDLSP LERGSQNPQL VDYSLQKQRA YDGIADLVLS CQAVSAPLGD EWAEMRGDTL 670 680 690 700 710 720 ETRLAGVRSV SRQLQNYVAQ IGFSLTLLLE QAPSEAPPAR DIGGASLSKV PSGSIGMPSA 730 740 750 760 770 780 YPPADRQPVK SRANIDKAQR FFGDTIPTEP AMQWYLNIDH ESEVFYDNKG EVPTLKCGTL 790 800 810 820 830 840 AGLVEHLTRH DKLDTSFNST FLLTYRSFTT ASELFEMLVH RFTLQPPYGL DKTDLQTWTE 850 860 870 880 890 900 QKQIPIRIRV VNIMKNWFEN YWMEPNDDAN MRLLQRVYAF VKDSIGKAKT PGSQQLLSLI 910 920 930 940 950 960 DQRMRGQDTS AKRLVPTISG NAPPPILPKN LKKLKFLDID PMEFARQLTI IESRLYARIK 970 980 990 1000 1010 1020 PTECLNKTWQ KKLVPDEPDP AANVKALILH SNQLTNWVAE MILHQQDVKR RVVVIKHFVL 1030 1040 1050 1060 1070 1080 IAERCRAMNN YSTLTSIISA LGTAPVHRLN RTWAQVSARI LAVLENMRRL MASTKNFGEY 1090 1100 1110 1120 1130 1140 REALHLANPP CIPFFGVYLT DLTFIEDGIP SLTQSHLINF NKRAKTAEVI RDIQQYQNAP 1150 1160 1170 1180 1190 1200 YPFHPVPELQ DYVLSNMQAA GDVHEMYDRS LEVEPRERED EKIARYGQMN DASVFALMIS T

References

[1]

"Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives." Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N. , Orbach M.J., Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W. Genome Res. 19:1722-1731(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NAm1 / WU24.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH476660 Genomic DNA. Translation: EDN09273.1.
RefSeq	XP_001538835.1. XM_001538785.1.
3D structure databases
ProteinModelPortal	A6R7Z9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5445139.
KEGG	aje:HCAG_06440.
Family and domain databases
Gene3D	1.10.840.10. 1 hit.
InterPro	IPR000651. Ras-like_Gua-exchang_fac_N. IPR019804. Ras_G-nucl-exch_fac_CS. IPR008937. Ras_GEF. IPR023578. Ras_GEF_dom. IPR001895. RasGRF_CDC25. IPR001452. SH3_domain. [Graphical view]
PANTHER	PTHR23113. PTHR23113. 1 hit.
Pfam	PF00617. RasGEF. 1 hit. PF00618. RasGEF_N. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00452. SH3DOMAIN.
SMART	SM00147. RasGEF. 1 hit. SM00229. RasGEFN. 1 hit. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF48366. Ras_GEF. 1 hit. SSF50044. SH3. 1 hit.
PROSITE	PS00720. RASGEF. 1 hit. PS50009. RASGEF_CAT. 1 hit. PS50212. RASGEF_NTER. 1 hit. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6R7Z9_AJECN

Accession

Primary (citable) accession number: A6R7Z9

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	March 6, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)