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A6R7Z9

- A6R7Z9_AJECN

UniProt

A6R7Z9 - A6R7Z9_AJECN

Protein
Submitted name:

Putative uncharacterized protein

Gene

HCAG_06440

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. guanyl-nucleotide exchange factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of small GTPase mediated signal transduction Source: InterPro
    2. small GTPase mediated signal transduction Source: InterPro

    Keywords - Molecular functioni

    Guanine-nucleotide releasing factorSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    ORF Names:HCAG_06440Imported
    OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
    Taxonomic identifieri339724 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeAjellomyces
    ProteomesiUP000009297: Unassembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliA6R7Z9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SH3 domain.UniRule annotation
    Contains N-terminal Ras-GEF domain.SAAS annotation
    Contains Ras-GEF domain.SAAS annotation

    Keywords - Domaini

    SH3 domainUniRule annotation

    Phylogenomic databases

    OrthoDBiEOG78WM2F.

    Family and domain databases

    Gene3Di1.10.840.10. 1 hit.
    InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
    IPR019804. Ras_G-nucl-exch_fac_CS.
    IPR023578. Ras_GEF_dom.
    IPR001895. RasGRF_CDC25.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00617. RasGEF. 1 hit.
    PF00618. RasGEF_N. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00147. RasGEF. 1 hit.
    SM00229. RasGEFN. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF48366. SSF48366. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEiPS00720. RASGEF. 1 hit.
    PS50009. RASGEF_CAT. 1 hit.
    PS50212. RASGEF_NTER. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6R7Z9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYSSRSAVPL TVNSKSVLNA KPGTFAAAFH YTEDEALSSN DNSQYHSTNN     50
    HSYHADMARH HGNDGYVESP PALYVRALYN YTADDHTSLS FRQGDIIQVL 100
    NQLDTGWWDG VMGDVRGWFP SNYCAVVTDP DSIGLGGGHF GHESGDISAE 150
    SGADDYDDDD DLDSEGNSKD ERSILPTEGT RGSEHEEAAF WIPQATADGR 200
    LFYFNTLTGR STAELPLESP MSATETGPRD RTNIFVPEQT RPPPELMVGG 250
    IDRDEDDYDG SGSEAEGESL IRSSHDSESR RRRSFISDGV SPATSLDSIN 300
    ASPIVISYSE SKHTHQSPPS SSGQLPSNSG VLSSAANAQP AQNERLSSQS 350
    ISSTIPRLFL DDGSSTPLTW NKLVGNMRQA IDAYRRAIME GHREQYVRRA 400
    EDISDHLRML LAAGSDTTDN HSGNPSIIST NKALYPHFRD MMSKFSKLVL 450
    SSHIAAADWR GPDSDAKCLQ EAEGVLHGVY GYVEVAKQQR GDDISRLVPG 500
    FVQGSSSGGH WQNNNVGIRN PTTFLDYENQ DSGLEPTVVL NSNIVYRIEN 550
    LKDMLAASTR RLEENLSLSE KTITPRIHLA IADTVCAACS RVVECFQPWM 600
    SLVESIDLSP LERGSQNPQL VDYSLQKQRA YDGIADLVLS CQAVSAPLGD 650
    EWAEMRGDTL ETRLAGVRSV SRQLQNYVAQ IGFSLTLLLE QAPSEAPPAR 700
    DIGGASLSKV PSGSIGMPSA YPPADRQPVK SRANIDKAQR FFGDTIPTEP 750
    AMQWYLNIDH ESEVFYDNKG EVPTLKCGTL AGLVEHLTRH DKLDTSFNST 800
    FLLTYRSFTT ASELFEMLVH RFTLQPPYGL DKTDLQTWTE QKQIPIRIRV 850
    VNIMKNWFEN YWMEPNDDAN MRLLQRVYAF VKDSIGKAKT PGSQQLLSLI 900
    DQRMRGQDTS AKRLVPTISG NAPPPILPKN LKKLKFLDID PMEFARQLTI 950
    IESRLYARIK PTECLNKTWQ KKLVPDEPDP AANVKALILH SNQLTNWVAE 1000
    MILHQQDVKR RVVVIKHFVL IAERCRAMNN YSTLTSIISA LGTAPVHRLN 1050
    RTWAQVSARI LAVLENMRRL MASTKNFGEY REALHLANPP CIPFFGVYLT 1100
    DLTFIEDGIP SLTQSHLINF NKRAKTAEVI RDIQQYQNAP YPFHPVPELQ 1150
    DYVLSNMQAA GDVHEMYDRS LEVEPRERED EKIARYGQMN DASVFALMIS 1200
    T 1201
    Length:1,201
    Mass (Da):133,821
    Last modified:August 21, 2007 - v1
    Checksum:i42EA3CCDC5E6E530
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476660 Genomic DNA. Translation: EDN09273.1.
    RefSeqiXP_001538835.1. XM_001538785.1.

    Genome annotation databases

    GeneIDi5445139.
    KEGGiaje:HCAG_06440.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476660 Genomic DNA. Translation: EDN09273.1 .
    RefSeqi XP_001538835.1. XM_001538785.1.

    3D structure databases

    ProteinModelPortali A6R7Z9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5445139.
    KEGGi aje:HCAG_06440.

    Phylogenomic databases

    OrthoDBi EOG78WM2F.

    Family and domain databases

    Gene3Di 1.10.840.10. 1 hit.
    InterProi IPR000651. Ras-like_Gua-exchang_fac_N.
    IPR019804. Ras_G-nucl-exch_fac_CS.
    IPR023578. Ras_GEF_dom.
    IPR001895. RasGRF_CDC25.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00617. RasGEF. 1 hit.
    PF00618. RasGEF_N. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00147. RasGEF. 1 hit.
    SM00229. RasGEFN. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48366. SSF48366. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEi PS00720. RASGEF. 1 hit.
    PS50009. RASGEF_CAT. 1 hit.
    PS50212. RASGEF_NTER. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NAm1 / WU24Imported.

    Entry informationi

    Entry nameiA6R7Z9_AJECN
    AccessioniPrimary (citable) accession number: A6R7Z9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3