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Protein
Submitted name:

Putative uncharacterized protein

Gene

HCAG_06440

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factorSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
ORF Names:HCAG_06440Imported
OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
Taxonomic identifieri339724 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeHistoplasma
ProteomesiUP000009297 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:HCAG_06440.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliA6R7Z9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation
Contains N-terminal Ras-GEF domain.SAAS annotation
Contains Ras-GEF domain.SAAS annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

OrthoDBiEOG78WM2F.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6R7Z9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSSRSAVPL TVNSKSVLNA KPGTFAAAFH YTEDEALSSN DNSQYHSTNN
60 70 80 90 100
HSYHADMARH HGNDGYVESP PALYVRALYN YTADDHTSLS FRQGDIIQVL
110 120 130 140 150
NQLDTGWWDG VMGDVRGWFP SNYCAVVTDP DSIGLGGGHF GHESGDISAE
160 170 180 190 200
SGADDYDDDD DLDSEGNSKD ERSILPTEGT RGSEHEEAAF WIPQATADGR
210 220 230 240 250
LFYFNTLTGR STAELPLESP MSATETGPRD RTNIFVPEQT RPPPELMVGG
260 270 280 290 300
IDRDEDDYDG SGSEAEGESL IRSSHDSESR RRRSFISDGV SPATSLDSIN
310 320 330 340 350
ASPIVISYSE SKHTHQSPPS SSGQLPSNSG VLSSAANAQP AQNERLSSQS
360 370 380 390 400
ISSTIPRLFL DDGSSTPLTW NKLVGNMRQA IDAYRRAIME GHREQYVRRA
410 420 430 440 450
EDISDHLRML LAAGSDTTDN HSGNPSIIST NKALYPHFRD MMSKFSKLVL
460 470 480 490 500
SSHIAAADWR GPDSDAKCLQ EAEGVLHGVY GYVEVAKQQR GDDISRLVPG
510 520 530 540 550
FVQGSSSGGH WQNNNVGIRN PTTFLDYENQ DSGLEPTVVL NSNIVYRIEN
560 570 580 590 600
LKDMLAASTR RLEENLSLSE KTITPRIHLA IADTVCAACS RVVECFQPWM
610 620 630 640 650
SLVESIDLSP LERGSQNPQL VDYSLQKQRA YDGIADLVLS CQAVSAPLGD
660 670 680 690 700
EWAEMRGDTL ETRLAGVRSV SRQLQNYVAQ IGFSLTLLLE QAPSEAPPAR
710 720 730 740 750
DIGGASLSKV PSGSIGMPSA YPPADRQPVK SRANIDKAQR FFGDTIPTEP
760 770 780 790 800
AMQWYLNIDH ESEVFYDNKG EVPTLKCGTL AGLVEHLTRH DKLDTSFNST
810 820 830 840 850
FLLTYRSFTT ASELFEMLVH RFTLQPPYGL DKTDLQTWTE QKQIPIRIRV
860 870 880 890 900
VNIMKNWFEN YWMEPNDDAN MRLLQRVYAF VKDSIGKAKT PGSQQLLSLI
910 920 930 940 950
DQRMRGQDTS AKRLVPTISG NAPPPILPKN LKKLKFLDID PMEFARQLTI
960 970 980 990 1000
IESRLYARIK PTECLNKTWQ KKLVPDEPDP AANVKALILH SNQLTNWVAE
1010 1020 1030 1040 1050
MILHQQDVKR RVVVIKHFVL IAERCRAMNN YSTLTSIISA LGTAPVHRLN
1060 1070 1080 1090 1100
RTWAQVSARI LAVLENMRRL MASTKNFGEY REALHLANPP CIPFFGVYLT
1110 1120 1130 1140 1150
DLTFIEDGIP SLTQSHLINF NKRAKTAEVI RDIQQYQNAP YPFHPVPELQ
1160 1170 1180 1190 1200
DYVLSNMQAA GDVHEMYDRS LEVEPRERED EKIARYGQMN DASVFALMIS

T
Length:1,201
Mass (Da):133,821
Last modified:August 21, 2007 - v1
Checksum:i42EA3CCDC5E6E530
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476660 Genomic DNA. Translation: EDN09273.1.
RefSeqiXP_001538835.1. XM_001538785.1.

Genome annotation databases

GeneIDi5445139.
KEGGiaje:HCAG_06440.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476660 Genomic DNA. Translation: EDN09273.1.
RefSeqiXP_001538835.1. XM_001538785.1.

3D structure databases

ProteinModelPortaliA6R7Z9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5445139.
KEGGiaje:HCAG_06440.

Organism-specific databases

EuPathDBiFungiDB:HCAG_06440.

Phylogenomic databases

OrthoDBiEOG78WM2F.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NAm1 / WU24Imported.

Entry informationi

Entry nameiA6R7Z9_AJECN
AccessioniPrimary (citable) accession number: A6R7Z9
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: May 27, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.