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Protein

Glutamate decarboxylase

Gene

HCAG_05038

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:HCAG_05038Imported
OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
Taxonomic identifieri339724 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeHistoplasma
Proteomesi
  • UP000009297 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:HCAG_05038

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei302N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi339724.XP_001539571.1

Structurei

3D structure databases

ProteinModelPortaliA6R5Y0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1383 Eukaryota
COG0076 LUCA
KOiK01580
OrthoDBiEOG092C1P0W

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 2 hits
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

A6R5Y0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLAAHVDVN QLIEDLRNDP KRRKSERLWT ENVSGSMTPY STRYASHEEI
60 70 80 90 100
PKFKLPEKGA PAEAVRRMLR DDLDLDGIPN LNLASFVGTY MEREADELLF
110 120 130 140 150
ENISKNLADA DEYPALMEMH AHCVSMISNL WHAQPGEHAI GSATTGSSEA
160 170 180 190 200
ILLGGLAMKK RWQETKKAAG KDTSKPNIIM GANAQVALLK FARYFDVEAR
210 220 230 240 250
ILDVSQKSEY RLDPDLVKKN LDENTIGVFV IMGSTYTGHY EPVEEISNIL
260 270 280 290 300
DEFEAKTGID VPIHVDGASG AFVAPFTYAQ AGGPKWDFAL PRVKSINTSG
310 320 330 340 350
HKFGLVYAGL GWIVWRDRTY LPSDLIFELH YLGGTEETFT LNFSRPGMQV
360 370 380 390 400
VGQYYNFIRL GFNGYREIME NCLANARLLS TALENTGWFL CISGIHRKNG
410 420 430 440 450
SSKVEQTNGL LKYQEGETSA DYNAGLPVVS FRFSDEVQQK YPDVKQESVS
460 470 480 490 500
LLLRAKQYII PNYPLPPAED KTETLRIVVR ESMSADLIDR LVADIVAVTE
510 520 530 540 550
RLMASEPVDV AALQTGPTSI ARRLVSTVLE NKSAISSIGM IFAWNRGGCH
Length:550
Mass (Da):61,231
Last modified:August 21, 2007 - v1
Checksum:iE3EB8D60DCD42B2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476659 Genomic DNA Translation: EDN08539.1
RefSeqiXP_001539571.1, XM_001539521.1

Genome annotation databases

EnsemblFungiiEDN08539; EDN08539; HCAG_05038
GeneIDi5445909
KEGGiaje:HCAG_05038

Similar proteinsi

Entry informationi

Entry nameiA6R5Y0_AJECN
AccessioniPrimary (citable) accession number: A6R5Y0
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 25, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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