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A6R213

- ACUK_AJECN

UniProt

A6R213 - ACUK_AJECN

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Protein

Transcription activator of gluconeogenesis HCAG_03671

Gene
HCAG_03671
Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes By similarity.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi77 – 10529Zn(2)-C6 fungal-typeAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis HCAG_03671
Gene namesi
ORF Names:HCAG_03671
OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Taxonomic identifieri339724 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeAjellomyces
ProteomesiUP000009297: Unassembled WGS sequence

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 776776Transcription activator of gluconeogenesis HCAG_03671PRO_0000406425Add
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi660 – 6689Poly-Gly

Sequence similaritiesi

Belongs to the ERT1/acuK family.

Phylogenomic databases

OrthoDBiEOG70KGZB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6R213-1 [UniParc]FASTAAdd to Basket

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MTASTQNGSP TPPPAAPTAT NQESKNMTAN PADASESQSP ANEKGGGTAE    50
NGQKHTSTAA NAKDPLRPRR KKAKRACFAC QRAHLTCGDE RPCQRCIKRG 100
LQDACHDGVR KKAKYLHDAP NEALMPGIRR NFYNQANATR TNASQQQNGP 150
NSNSNKDSRQ NVAANFYSPQ SASNFDVYTQ AKSQQGQGHI PPTVMQDTSI 200
NPSAFQAPSP TSTPNFDLSS NPPNRNLSSA MTQTPSSASN QTQDPFGAAF 250
FDPSHPALFN FDIASMNFGN RYGALEFGML GHMATGAGDT PPSDSATQRG 300
SIGRSSGTFT AQNFGDSTNT QPPFLFGDPV LNDWNPSGQS QTNPRNNNIY 350
NQNTVAGQMG EQHPNAFAIE SAPMNFASPG STESPQMTTM NQFDEANAKF 400
SSRTALMHQT NPHQPPPIST PGLKHQGFQV GVKRRYRSPS SIYESVKEPY 450
SYTSGFHNLT AFIQRRFSPQ KTLQIAKALA SIRPSFIATT KTLNQDDLIF 500
MEKCFQRTLW EYEDFINACG TPTIVCRRTG EIAAVGKEFS ILTGWKKEVL 550
LGKEPNLNVN TGGSSPRGSG TFTPRNGNGV DPHSGMSASG GGGGRTQPVF 600
LAELLDDDSV IEFYEDFAKL AFGDSRGSVM TTCKLLKYKT KEDSAALFQG 650
REAQQGGPDG KGGGGGGGDV ATTAATTSTS TSNGANSSGH ANANRNNTNP 700
NNSSPPSSSS AAAAGPLHGA QLSPKQTWGK RGIAGEAGMN QLGFRDGKVE 750
CSYCWTVKRD VFDIPMLIVM NFLPCI 776
Length:776
Mass (Da):82,947
Last modified:August 21, 2007 - v1
Checksum:i96B29880BC6DE8AA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH476657 Genomic DNA. Translation: EDN07140.1.
RefSeqiXP_001541573.1. XM_001541523.1.

Genome annotation databases

GeneIDi5447923.
KEGGiaje:HCAG_03671.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH476657 Genomic DNA. Translation: EDN07140.1 .
RefSeqi XP_001541573.1. XM_001541523.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5447923.
KEGGi aje:HCAG_03671.

Phylogenomic databases

OrthoDBi EOG70KGZB.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
SMARTi SM00066. GAL4. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NAm1 / WU24.

Entry informationi

Entry nameiACUK_AJECN
AccessioniPrimary (citable) accession number: A6R213
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: August 21, 2007
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi