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A6R213

- ACUK_AJECN

UniProt

A6R213 - ACUK_AJECN

Protein

Transcription activator of gluconeogenesis HCAG_03671

Gene

HCAG_03671

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi77 – 10529Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Gluconeogenesis, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription activator of gluconeogenesis HCAG_03671
    Gene namesi
    ORF Names:HCAG_03671
    OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
    Taxonomic identifieri339724 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeAjellomyces
    ProteomesiUP000009297: Unassembled WGS sequence

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 776776Transcription activator of gluconeogenesis HCAG_03671PRO_0000406425Add
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi660 – 6689Poly-Gly

    Sequence similaritiesi

    Belongs to the ERT1/acuK family.Curated
    Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    OrthoDBiEOG70KGZB.

    Family and domain databases

    Gene3Di4.10.240.10. 1 hit.
    InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view]
    SMARTiSM00066. GAL4. 1 hit.
    [Graphical view]
    SUPFAMiSSF57701. SSF57701. 1 hit.
    PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6R213-1 [UniParc]FASTAAdd to Basket

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    MTASTQNGSP TPPPAAPTAT NQESKNMTAN PADASESQSP ANEKGGGTAE    50
    NGQKHTSTAA NAKDPLRPRR KKAKRACFAC QRAHLTCGDE RPCQRCIKRG 100
    LQDACHDGVR KKAKYLHDAP NEALMPGIRR NFYNQANATR TNASQQQNGP 150
    NSNSNKDSRQ NVAANFYSPQ SASNFDVYTQ AKSQQGQGHI PPTVMQDTSI 200
    NPSAFQAPSP TSTPNFDLSS NPPNRNLSSA MTQTPSSASN QTQDPFGAAF 250
    FDPSHPALFN FDIASMNFGN RYGALEFGML GHMATGAGDT PPSDSATQRG 300
    SIGRSSGTFT AQNFGDSTNT QPPFLFGDPV LNDWNPSGQS QTNPRNNNIY 350
    NQNTVAGQMG EQHPNAFAIE SAPMNFASPG STESPQMTTM NQFDEANAKF 400
    SSRTALMHQT NPHQPPPIST PGLKHQGFQV GVKRRYRSPS SIYESVKEPY 450
    SYTSGFHNLT AFIQRRFSPQ KTLQIAKALA SIRPSFIATT KTLNQDDLIF 500
    MEKCFQRTLW EYEDFINACG TPTIVCRRTG EIAAVGKEFS ILTGWKKEVL 550
    LGKEPNLNVN TGGSSPRGSG TFTPRNGNGV DPHSGMSASG GGGGRTQPVF 600
    LAELLDDDSV IEFYEDFAKL AFGDSRGSVM TTCKLLKYKT KEDSAALFQG 650
    REAQQGGPDG KGGGGGGGDV ATTAATTSTS TSNGANSSGH ANANRNNTNP 700
    NNSSPPSSSS AAAAGPLHGA QLSPKQTWGK RGIAGEAGMN QLGFRDGKVE 750
    CSYCWTVKRD VFDIPMLIVM NFLPCI 776
    Length:776
    Mass (Da):82,947
    Last modified:August 21, 2007 - v1
    Checksum:i96B29880BC6DE8AA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476657 Genomic DNA. Translation: EDN07140.1.
    RefSeqiXP_001541573.1. XM_001541523.1.

    Genome annotation databases

    GeneIDi5447923.
    KEGGiaje:HCAG_03671.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476657 Genomic DNA. Translation: EDN07140.1 .
    RefSeqi XP_001541573.1. XM_001541523.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5447923.
    KEGGi aje:HCAG_03671.

    Phylogenomic databases

    OrthoDBi EOG70KGZB.

    Family and domain databases

    Gene3Di 4.10.240.10. 1 hit.
    InterProi IPR001138. Zn2-C6_fun-type_DNA-bd.
    [Graphical view ]
    SMARTi SM00066. GAL4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57701. SSF57701. 1 hit.
    PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NAm1 / WU24.

    Entry informationi

    Entry nameiACUK_AJECN
    AccessioniPrimary (citable) accession number: A6R213
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 5, 2011
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3