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Protein

Superoxide dismutase

Gene

HCAG_03448

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi29Divalent metal cationUniRule annotation1
Metal bindingi74Divalent metal cationUniRule annotation1
Metal bindingi162Divalent metal cationUniRule annotation1
Metal bindingi166Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
ORF Names:HCAG_03448Imported
OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
Taxonomic identifieri339724 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeHistoplasma
Proteomesi
  • UP000009297 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:HCAG_03448

Interactioni

Protein-protein interaction databases

STRINGi339724.XP_001541351.1

Structurei

3D structure databases

ProteinModelPortaliA6R1E1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 82Sod_Fe_NInterPro annotationAdd BLAST79
Domaini96 – 206Sod_Fe_CInterPro annotationAdd BLAST111

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0876 Eukaryota
COG0605 LUCA
KOiK04564
OrthoDBiEOG092C4NQ6

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

A6R1E1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQKYLLPRL PYAYNALEPV ISAQIMELHH AKHHNTYVTN LNKALQDRAA
60 70 80 90 100
ALKAGNKVDI QAIINFNAGG HINHTLLWQS MAPANVPESK VEAAPRLWEA
110 120 130 140 150
IRQQWGEDAD AFRKKFNEAL LGIRGSGWGW LVREGNQGPL AIVTTHDQDI
160 170 180 190 200
VAKHQVPIFA VDMWEHAYYL QLTSNFFRGD LQYLNGKAAY VENIWNVINW
210 220
KGAEERYLGE STDSFEDLKA LM
Length:222
Mass (Da):25,196
Last modified:August 21, 2007 - v1
Checksum:i589C57255AB3A595
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476657 Genomic DNA Translation: EDN06918.1
RefSeqiXP_001541351.1, XM_001541301.1

Genome annotation databases

EnsemblFungiiEDN06918; EDN06918; HCAG_03448
GeneIDi5447911
KEGGiaje:HCAG_03448

Similar proteinsi

Entry informationi

Entry nameiA6R1E1_AJECN
AccessioniPrimary (citable) accession number: A6R1E1
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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