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Protein

Hexokinase

Gene

HCAG_03191

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:HCAG_03191Imported
OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
Taxonomic identifieri339724 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeHistoplasma
ProteomesiUP000009297 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6R0N4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSPVIDEA RRIAELFEYP TEDVHRGVKE FIRQMDEGLE QDGATLRQIL
60 70 80 90 100
SYVTAVPDGT EKGVYLAVDL GGTNFRVCCV DLHGDSTFSI SQSKVAIPPE
110 120 130 140 150
LMVTRHGREL FSFLALQIEE FLRTHLSDHF AAHVERRQTG EVIDPYVDEQ
160 170 180 190 200
IFDMGFTFSF PVDQQGINKG KLIRWTKGFD IDEVIGQDVC KLLQDAIDQR
210 220 230 240 250
QLPVRVAALV NDTVGTLMAR SYCSGQHSKA LIGAIFGTGT NGAYVEKLAR
260 270 280 290 300
ITKMDKVNPD TQYDRTTGEM VINVEWGSFD NHLSVLPNTR FDAALDAHSV
310 320 330 340 350
NPGIQMFEKR VSGMFLGEIL RRALLAMSED PAVSLFRTTN DRAAMTIPPD
360 370 380 390 400
SGLYRAWGID TSFLSTVKAD ELPNLDATRA QLKQELQIDN ASTDDCRAVK
410 420 430 440 450
ILVHAIGKRA ARLSAVALAA VIISTGKLRE GPDVLADIGV DGSVVEHYPG
460 470 480 490 500
FEEYMRQAFR EIAEIGEEGE KRITLGVAKD GSGVGAALGA LVAREVARRG
Length:500
Mass (Da):54,937
Last modified:August 21, 2007 - v1
Checksum:iA8D116F9BE090AA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476657 Genomic DNA. Translation: EDN06661.1.
RefSeqiXP_001541094.1. XM_001541044.1.

Genome annotation databases

GeneIDi5448166.
KEGGiaje:HCAG_03191.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476657 Genomic DNA. Translation: EDN06661.1.
RefSeqiXP_001541094.1. XM_001541044.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5448166.
KEGGiaje:HCAG_03191.

Phylogenomic databases

KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NAm1 / WU24Imported.

Entry informationi

Entry nameiA6R0N4_AJECN
AccessioniPrimary (citable) accession number: A6R0N4
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 1, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.