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A6QZ20

- A6QZ20_AJECN

UniProt

A6QZ20 - A6QZ20_AJECN

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Protein

DNA ligase

Gene
HCAG_02627
Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:HCAG_02627Imported
OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
Taxonomic identifieri339724 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeAjellomyces
ProteomesiUP000009297: Unassembled WGS sequence

PTM / Processingi

Proteomic databases

PRIDEiA6QZ20.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6QZ20-1 [UniParc]FASTAAdd to Basket

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MDSDGEGEPN GSRQQDSTAN DLDEKYPNPP RNHSPTLPFH DLFLTLFNPL    50
NENKKRPTGP AAARRKVGPH GQGAAVHLSP QERRRDIIQR FISRWRKEVG 100
DDIFPAFRLI IPEKDRDRAM YGLKEKAIGK LLVKVMKIDK NSEDGFSLLN 150
WKVPGQSFAS RMAGDFAGRC FEVISKRPLR TEVGDMTIDE VNEQLDKLSA 200
ASKEDEQVPI LAYFYRRMNP EELMWLIRII LRQMKVGATE RTFFSIWHPD 250
AEALFSISSS LRRVCWQLYN TDVRLEGDET KVTLMQCFQP QLAQFQMQSF 300
EHMIRRMRLT EDDPTFWIEE KLDGERIQLH MKPDDSIPGG KRFGFWSRKA 350
KEYTYLYGNG LLDENGALTR HLQDAFADGV QSIILDGEMI TWDPEHDAIV 400
PFGTLKTAAL AEQRNPFSTG QRPLFRIFDI LYLNGRPLTR YTLKDRRKAL 450
EASVIPVHRR FEIHTYDIGH SATDIDPLLR KVVAEASEGL VLKNPNSPYR 500
LNERHDDWMK VKPEYMTDFG ESLDCIVIGG YYGSGRRGGA LSSFLCGLRV 550
DGSHSKTGDH PTKCYSFCKV GGGFTAADYA NIRHHTDGKW MDWDPKRPPT 600
EYIELAGGDL QYERPDVWIK PEDSVVLCVK ASSVTSTDQF RLGLTVRFPR 650
FKRLRMDKDW RSALSIQEFM DLKSNVEREV KEKEFKVDDS RKVRHRKAIK 700
KPLTIAGYDG GKKLEYVGPS GTLFDGLNFF IMTESVHQPK KTKAQLEQLV 750
KANGGKIYQT NNVAENTICI ADRTDQEEEI AEHVDKYSDS YARDIDASEL 800
KKLLDSMHPA PALPPSSLSE LESQLESHSL NERKPATPTI SNTSTCPGWL 850
FKGLVIYFAM PPSLSNEGNG KIPHVLPQRL YLASNLVKFA GGEVITDDDG 900
DMKDARITHV VVDSNPPGDK AAMAAADVAG IRRAISSRAG VGKRIPHIVG 950
VEWVEESWGE RTLVDEERFT PK 972
Length:972
Mass (Da):110,245
Last modified:August 21, 2007 - v1
Checksum:i75EE296AB02C7DA5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH476656 Genomic DNA. Translation: EDN06024.1.
RefSeqiXP_001542456.1. XM_001542406.1.

Genome annotation databases

GeneIDi5448693.
KEGGiaje:HCAG_02627.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH476656 Genomic DNA. Translation: EDN06024.1 .
RefSeqi XP_001542456.1. XM_001542406.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi A6QZ20.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5448693.
KEGGi aje:HCAG_02627.

Phylogenomic databases

KOi K10777.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NAm1 / WU24.

Entry informationi

Entry nameiA6QZ20_AJECN
AccessioniPrimary (citable) accession number: A6QZ20
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: January 22, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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