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A6QZ20

- A6QZ20_AJECN

UniProt

A6QZ20 - A6QZ20_AJECN

Protein

DNA ligase

Gene

HCAG_02627

Organism
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:HCAG_02627Imported
    OrganismiAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)Imported
    Taxonomic identifieri339724 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesAjellomycetaceaeAjellomyces
    ProteomesiUP000009297: Unassembled WGS sequence

    PTM / Processingi

    Proteomic databases

    PRIDEiA6QZ20.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK10777.
    OrthoDBiEOG7QC84G.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.40.50.10190. 2 hits.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6QZ20-1 [UniParc]FASTAAdd to Basket

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    MDSDGEGEPN GSRQQDSTAN DLDEKYPNPP RNHSPTLPFH DLFLTLFNPL    50
    NENKKRPTGP AAARRKVGPH GQGAAVHLSP QERRRDIIQR FISRWRKEVG 100
    DDIFPAFRLI IPEKDRDRAM YGLKEKAIGK LLVKVMKIDK NSEDGFSLLN 150
    WKVPGQSFAS RMAGDFAGRC FEVISKRPLR TEVGDMTIDE VNEQLDKLSA 200
    ASKEDEQVPI LAYFYRRMNP EELMWLIRII LRQMKVGATE RTFFSIWHPD 250
    AEALFSISSS LRRVCWQLYN TDVRLEGDET KVTLMQCFQP QLAQFQMQSF 300
    EHMIRRMRLT EDDPTFWIEE KLDGERIQLH MKPDDSIPGG KRFGFWSRKA 350
    KEYTYLYGNG LLDENGALTR HLQDAFADGV QSIILDGEMI TWDPEHDAIV 400
    PFGTLKTAAL AEQRNPFSTG QRPLFRIFDI LYLNGRPLTR YTLKDRRKAL 450
    EASVIPVHRR FEIHTYDIGH SATDIDPLLR KVVAEASEGL VLKNPNSPYR 500
    LNERHDDWMK VKPEYMTDFG ESLDCIVIGG YYGSGRRGGA LSSFLCGLRV 550
    DGSHSKTGDH PTKCYSFCKV GGGFTAADYA NIRHHTDGKW MDWDPKRPPT 600
    EYIELAGGDL QYERPDVWIK PEDSVVLCVK ASSVTSTDQF RLGLTVRFPR 650
    FKRLRMDKDW RSALSIQEFM DLKSNVEREV KEKEFKVDDS RKVRHRKAIK 700
    KPLTIAGYDG GKKLEYVGPS GTLFDGLNFF IMTESVHQPK KTKAQLEQLV 750
    KANGGKIYQT NNVAENTICI ADRTDQEEEI AEHVDKYSDS YARDIDASEL 800
    KKLLDSMHPA PALPPSSLSE LESQLESHSL NERKPATPTI SNTSTCPGWL 850
    FKGLVIYFAM PPSLSNEGNG KIPHVLPQRL YLASNLVKFA GGEVITDDDG 900
    DMKDARITHV VVDSNPPGDK AAMAAADVAG IRRAISSRAG VGKRIPHIVG 950
    VEWVEESWGE RTLVDEERFT PK 972
    Length:972
    Mass (Da):110,245
    Last modified:August 21, 2007 - v1
    Checksum:i75EE296AB02C7DA5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476656 Genomic DNA. Translation: EDN06024.1.
    RefSeqiXP_001542456.1. XM_001542406.1.

    Genome annotation databases

    GeneIDi5448693.
    KEGGiaje:HCAG_02627.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476656 Genomic DNA. Translation: EDN06024.1 .
    RefSeqi XP_001542456.1. XM_001542406.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A6QZ20.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5448693.
    KEGGi aje:HCAG_02627.

    Phylogenomic databases

    KOi K10777.
    OrthoDBi EOG7QC84G.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.40.50.10190. 2 hits.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NAm1 / WU24Imported.

    Entry informationi

    Entry nameiA6QZ20_AJECN
    AccessioniPrimary (citable) accession number: A6QZ20
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3