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Protein

Aldehyde dehydrogenase family 16 member A1

Gene

ALDH16A1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase family 16 member A1
Gene namesi
Name:ALDH16A1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 800800Aldehyde dehydrogenase family 16 member A1PRO_0000312985Add
BLAST

Proteomic databases

PaxDbiA6QR56.
PeptideAtlasiA6QR56.
PRIDEiA6QR56.

Interactioni

Subunit structurei

Interacts with SPG21.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000040728.

Structurei

3D structure databases

ProteinModelPortaliA6QR56.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiKOG2450. Eukaryota.
COG1012. LUCA.
HOGENOMiHOG000112558.
HOVERGENiHBG069396.
InParanoidiA6QR56.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 2 hits.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR011408. Aldehyde_DH.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 2 hits.
[Graphical view]
PIRSFiPIRSF036490. Aldedh_dupl. 1 hit.
SUPFAMiSSF53720. SSF53720. 2 hits.

Sequencei

Sequence statusi: Complete.

A6QR56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATRTASRA CEIFTTLEYG PAPESHACAL AWLDTQDRHL GHYVNGQWLK
60 70 80 90 100
PEHRSSVPCQ DPITGENLAS CLQAQSEDVA AAVEAARASL ENWSTQPGAI
110 120 130 140 150
RAQHLTRLAK VIQKHQRLLW TLESLVTGRA VREVRDRDVP LAQQLLQYHA
160 170 180 190 200
VQAHTQEEAL AGWEPMGVIG LILSPTFPFL DMMWRICPAL AVGCTVVVLV
210 220 230 240 250
PPASPTPLLL AQLAGELGPF PGILNVISGP ASLGPVLAAQ PGVQKVAFCG
260 270 280 290 300
AIEEGRALRR TLAGWVPELG LALGAESLLL LTEVADVDSA VEGIVDAAWS
310 320 330 340 350
DRSPGGLRLL IQEAVWDETM RRLQERMGRL RCGHGLDGAV DMGARGAAAR
360 370 380 390 400
DLAQRYVSEA QSQGAQVFQA GSEPSDSPFF PPTLVSDLPP ASPCTQAEVP
410 420 430 440 450
WPLVVASPFR TAKEALAVAN GTPRGGSASV WSERLGQALE LAYGLQVGTV
460 470 480 490 500
WINAHGLRDP AVPTGGCKES GSSWHGGQDG LYEYLRPSGT PAWIPYLSKT
510 520 530 540 550
LNYDAFGLAL PSTLPAGPET GPAPPYGLFV GGRFQAPGAR SSRPIQDSQG
560 570 580 590 600
SLQGYVAEGG AKDIRGAVEA AHQAAPGWMS QSPAARAALL WALAAALQRR
610 620 630 640 650
EPNLVSRLER HGVELKVAKA EVELSVKRLR AWGARVQAQG CALQVAELRG
660 670 680 690 700
PVLRLREPLG VLAIVCPDEW PLLAFVSLLA PALAHGNTVV LVPSGACPIP
710 720 730 740 750
ALEVCQEMAT LLPAGLVNVV TGDRDHLTRC LALHQDIQAL WYFGSAQGSQ
760 770 780 790 800
FVEWASAGNL KPVWVNRGCP RAWDQEAEGA GPELGRRAAR TKALWLPMGD
Length:800
Mass (Da):85,168
Last modified:August 21, 2007 - v1
Checksum:i0FC45E8431D2CDA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC150121 mRNA. Translation: AAI50122.1.
RefSeqiNP_001095339.1. NM_001101869.1.
UniGeneiBt.20967.

Genome annotation databases

GeneIDi506329.
KEGGibta:506329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC150121 mRNA. Translation: AAI50122.1.
RefSeqiNP_001095339.1. NM_001101869.1.
UniGeneiBt.20967.

3D structure databases

ProteinModelPortaliA6QR56.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000040728.

Proteomic databases

PaxDbiA6QR56.
PeptideAtlasiA6QR56.
PRIDEiA6QR56.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi506329.
KEGGibta:506329.

Organism-specific databases

CTDi126133.

Phylogenomic databases

eggNOGiKOG2450. Eukaryota.
COG1012. LUCA.
HOGENOMiHOG000112558.
HOVERGENiHBG069396.
InParanoidiA6QR56.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 2 hits.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR011408. Aldehyde_DH.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 2 hits.
[Graphical view]
PIRSFiPIRSF036490. Aldedh_dupl. 1 hit.
SUPFAMiSSF53720. SSF53720. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA16A1_BOVIN
AccessioniPrimary (citable) accession number: A6QR56
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: July 6, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Caution

The active site cysteine and glutamate residues are not conserved in this protein. Its activity is therefore unsure.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.