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Protein
Submitted name:

LTBR protein

Gene

LTBR

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-BTA-5668541. TNFR2 non-canonical NF-kB pathway.
R-BTA-5676594. TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
LTBR proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:LTBRImported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei230 – 25324HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence analysisAdd
BLAST
Chaini28 – 428401Sequence analysisPRO_5007635806Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000020355.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 8739TNFR-CysInterPro annotationAdd
BLAST
Domaini89 – 13143TNFR-CysInterPro annotationAdd
BLAST
Domaini176 – 21742TNFR-CysInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IKNN. Eukaryota.
ENOG410YQJW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000294180.
HOVERGENiHBG023187.
KOiK03159.
OMAiQLCRPCD.
OrthoDBiEOG786H2Q.
TreeFamiTF331157.

Family and domain databases

InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
IPR017349. TNFR_3_LTBR.
[Graphical view]
PfamiPF00020. TNFR_c6. 3 hits.
[Graphical view]
PRINTSiPR01920. TNFACTORR3.
SMARTiSM00208. TNFR. 4 hits.
[Graphical view]
PROSITEiPS00652. TNFR_NGFR_1. 2 hits.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6QQ46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLWATSHR GLAWGLLILG VWGLLAASQP QLEREEPVQG LPYHTENQSC
60 70 80 90 100
GDQEKEYYES KLRLCCSRCP PGTHISTKCS RRQNTVCATC PEKSYNEHWN
110 120 130 140 150
HLSFCQLCRP CDKMLGFVEL TPCTSNRKAQ CHCQPGMYCV FWNSECEHCE
160 170 180 190 200
PLSDCPPGTE AELKDEVIEA NSNCVPCKAG HFQNTSSPTA RCRPHTRCED
210 220 230 240 250
QGLVEEAPGT PQSDTSCRNP QEPPDMPGTM LVLAILLPLV SFLLLTTVFV
260 270 280 290 300
YTWKSHPSLC RKLGSLLKRH PEGEESNPAD GNWEPPRFNT HVPDLVKPLL
310 320 330 340 350
PAPGDLALAS GGVPANPGLE EEVLQQQSPL SQARDLDAEP PEQGQVAPGT
360 370 380 390 400
NGIHVTGGSV TVTGNIYIYN GPVLGGARGP GDPPAPPEPP YPIPEEGAPR
410 420
PPGLSMPYQE DGKAWHLAET ETLGCYAL
Length:428
Mass (Da):46,724
Last modified:August 21, 2007 - v1
Checksum:i25AEB85B8557ACF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02014466 Genomic DNA. No translation available.
BC149639 mRNA. Translation: AAI49640.1.
RefSeqiNP_001096698.1. NM_001103228.2.
UniGeneiBt.38184.

Genome annotation databases

EnsembliENSBTAT00000020355; ENSBTAP00000020355; ENSBTAG00000015312.
GeneIDi504653.
KEGGibta:504653.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02014466 Genomic DNA. No translation available.
BC149639 mRNA. Translation: AAI49640.1.
RefSeqiNP_001096698.1. NM_001103228.2.
UniGeneiBt.38184.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000020355.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000020355; ENSBTAP00000020355; ENSBTAG00000015312.
GeneIDi504653.
KEGGibta:504653.

Organism-specific databases

CTDi4055.

Phylogenomic databases

eggNOGiENOG410IKNN. Eukaryota.
ENOG410YQJW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000294180.
HOVERGENiHBG023187.
KOiK03159.
OMAiQLCRPCD.
OrthoDBiEOG786H2Q.
TreeFamiTF331157.

Enzyme and pathway databases

ReactomeiR-BTA-5668541. TNFR2 non-canonical NF-kB pathway.
R-BTA-5676594. TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway.

Family and domain databases

InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
IPR017349. TNFR_3_LTBR.
[Graphical view]
PfamiPF00020. TNFR_c6. 3 hits.
[Graphical view]
PRINTSiPR01920. TNFACTORR3.
SMARTiSM00208. TNFR. 4 hits.
[Graphical view]
PROSITEiPS00652. TNFR_NGFR_1. 2 hits.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Crossbred x AngusImported.
    Tissue: IleumImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  3. Ensembl
    Submitted (MAR-2016) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiA6QQ46_BOVIN
AccessioniPrimary (citable) accession number: A6QQ46
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: July 6, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.