Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

LTBR protein

Gene

LTBR

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-5668541. TNFR2 non-canonical NF-kB pathway.
R-BTA-5676594. TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
LTBR proteinImported
Submitted name:
Lymphotoxin beta receptorImported
Gene namesi
Name:LTBRImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei230 – 253HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501108609528 – 428Sequence analysisAdd BLAST401

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi50 ↔ 65PROSITE-ProRule annotation
Disulfide bondi66 ↔ 79PROSITE-ProRule annotation
Disulfide bondi69 ↔ 87PROSITE-ProRule annotation
Disulfide bondi90 ↔ 105PROSITE-ProRule annotation
Disulfide bondi177 ↔ 192PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSBTAG00000015312.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000020355.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 87TNFR-CysInterPro annotationAdd BLAST39
Repeati49 – 87TNFR-CysPROSITE-ProRule annotationAdd BLAST39
Domaini89 – 131TNFR-CysInterPro annotationAdd BLAST43
Repeati89 – 131TNFR-CysPROSITE-ProRule annotationAdd BLAST43
Domaini176 – 217TNFR-CysInterPro annotationAdd BLAST42
Repeati176 – 217TNFR-CysPROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IKNN. Eukaryota.
ENOG410YQJW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000294180.
HOVERGENiHBG023187.
KOiK03159.
OMAiEDGKAWH.
OrthoDBiEOG091G03XW.
TreeFamiTF331157.

Family and domain databases

CDDicd10578. TNFRSF3. 1 hit.
InterProiView protein in InterPro
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR017349. TNFR_3_LTBR.
IPR033997. TNFRSF3_N.
PfamiView protein in Pfam
PF00020. TNFR_c6. 3 hits.
PRINTSiPR01920. TNFACTORR3.
SMARTiView protein in SMART
SM00208. TNFR. 4 hits.
PROSITEiView protein in PROSITE
PS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 3 hits.

Sequencei

Sequence statusi: Complete.

A6QQ46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLWATSHR GLAWGLLILG VWGLLAASQP QLEREEPVQG LPYHTENQSC
60 70 80 90 100
GDQEKEYYES KLRLCCSRCP PGTHISTKCS RRQNTVCATC PEKSYNEHWN
110 120 130 140 150
HLSFCQLCRP CDKMLGFVEL TPCTSNRKAQ CHCQPGMYCV FWNSECEHCE
160 170 180 190 200
PLSDCPPGTE AELKDEVIEA NSNCVPCKAG HFQNTSSPTA RCRPHTRCED
210 220 230 240 250
QGLVEEAPGT PQSDTSCRNP QEPPDMPGTM LVLAILLPLV SFLLLTTVFV
260 270 280 290 300
YTWKSHPSLC RKLGSLLKRH PEGEESNPAD GNWEPPRFNT HVPDLVKPLL
310 320 330 340 350
PAPGDLALAS GGVPANPGLE EEVLQQQSPL SQARDLDAEP PEQGQVAPGT
360 370 380 390 400
NGIHVTGGSV TVTGNIYIYN GPVLGGARGP GDPPAPPEPP YPIPEEGAPR
410 420
PPGLSMPYQE DGKAWHLAET ETLGCYAL
Length:428
Mass (Da):46,724
Last modified:August 21, 2007 - v1
Checksum:i25AEB85B8557ACF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02014466 Genomic DNA. No translation available.
BC149639 mRNA. Translation: AAI49640.1.
RefSeqiNP_001096698.1. NM_001103228.2.
UniGeneiBt.38184.

Genome annotation databases

EnsembliENSBTAT00000020355; ENSBTAP00000020355; ENSBTAG00000015312.
GeneIDi504653.
KEGGibta:504653.

Similar proteinsi

Entry informationi

Entry nameiA6QQ46_BOVIN
AccessioniPrimary (citable) accession number: A6QQ46
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported