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A6QPZ5

- A6QPZ5_BOVIN

UniProt

A6QPZ5 - A6QPZ5_BOVIN

Protein
Submitted name:

CBLC protein

Gene

CBLC

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. signal transducer activity Source: InterPro
    3. ubiquitin-protein transferase activity Source: Ensembl
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. cell surface receptor signaling pathway Source: InterPro
    2. negative regulation of epidermal growth factor-activated receptor activity Source: Ensembl
    3. negative regulation of MAP kinase activity Source: Ensembl
    4. protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CBLC proteinImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:CBLCImported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 18

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000041264.

    Structurei

    3D structure databases

    ProteinModelPortaliA6QPZ5.
    SMRiA6QPZ5. Positions 13-319.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Zinc-fingerUniRule annotation

    Phylogenomic databases

    eggNOGiNOG318595.
    GeneTreeiENSGT00390000011617.
    HOGENOMiHOG000294176.
    HOVERGENiHBG005255.
    InParanoidiA6QPZ5.
    KOiK04707.
    OMAiWQHSDSQ.
    OrthoDBiEOG73BVCF.
    TreeFamiTF314210.

    Family and domain databases

    Gene3Di1.10.238.10. 1 hit.
    1.20.930.20. 1 hit.
    3.30.40.10. 1 hit.
    3.30.505.10. 1 hit.
    InterProiIPR024162. Adaptor_Cbl.
    IPR014741. Adaptor_Cbl_EF_hand-like.
    IPR003153. Adaptor_Cbl_N_hlx.
    IPR014742. Adaptor_Cbl_SH2-like.
    IPR024159. Cbl_PTB.
    IPR011992. EF-hand-dom_pair.
    IPR000980. SH2.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR017907. Znf_RING_CS.
    [Graphical view]
    PANTHERiPTHR23007. PTHR23007. 1 hit.
    PfamiPF02262. Cbl_N. 1 hit.
    PF02761. Cbl_N2. 1 hit.
    PF02762. Cbl_N3. 1 hit.
    [Graphical view]
    SMARTiSM00184. RING. 1 hit.
    [Graphical view]
    SUPFAMiSSF47668. SSF47668. 1 hit.
    SSF55550. SSF55550. 1 hit.
    PROSITEiPS51506. CBL_PTB. 1 hit.
    PS00518. ZF_RING_1. 1 hit.
    PS50089. ZF_RING_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6QPZ5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAAALRGRQ WGESRAFGRA VRLLQRLEEQ CGDPRLSSSP PSLRDLLPRT    50
    AQLLRQVAQA RREAGGGVPE GPGGPWDFLM VYLANLEAKS RQVAALLPPH 100
    GRKIANDELF REGSRLRRQL AKLALIFSYM HAELDALFPG GRYCGHTYQL 150
    TKVSAHTFWR ERCGARCVLP WAEFEAVLCI CHPVEPGSTA LALRSTIDLT 200
    CSGHVSIFEF DIFTRLFQPW PTLLKNWQLL AVNHPGYMAF LTYDEVQARL 250
    QTFRDKPGSY IFRPSCTRLG KWAIGYVSSD GSILQTIPLN KPLFQVLLEG 300
    QKEGFYLYPD GKNHNPDLTE LCHMEPHQHI HVSEEQLQLY WAMDSTFELC 350
    KICAESNKDV KIEPCGHLLC SRCLAAWLCS DSQTCPFCRC EIKGQEAVSI 400
    HQFHVSATVE DPEHSSDEEE LEQMAPSGPP LPPRLDLCPK SPSSKGHLNV 450
    APPTLPRLRA PLPLPRFWTA ASAPWEVTSS PQAREGARGN S 491
    Length:491
    Mass (Da):54,955
    Last modified:August 21, 2007 - v1
    Checksum:iC3B9DD5706F88E66
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02047337 Genomic DNA. No translation available.
    BC149567 mRNA. Translation: AAI49568.1.
    RefSeqiNP_001094718.1. NM_001101248.2.
    UniGeneiBt.21193.

    Genome annotation databases

    EnsembliENSBTAT00000043713; ENSBTAP00000041264; ENSBTAG00000009494.
    GeneIDi615866.
    KEGGibta:615866.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02047337 Genomic DNA. No translation available.
    BC149567 mRNA. Translation: AAI49568.1 .
    RefSeqi NP_001094718.1. NM_001101248.2.
    UniGenei Bt.21193.

    3D structure databases

    ProteinModelPortali A6QPZ5.
    SMRi A6QPZ5. Positions 13-319.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000041264.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000043713 ; ENSBTAP00000041264 ; ENSBTAG00000009494 .
    GeneIDi 615866.
    KEGGi bta:615866.

    Organism-specific databases

    CTDi 23624.

    Phylogenomic databases

    eggNOGi NOG318595.
    GeneTreei ENSGT00390000011617.
    HOGENOMi HOG000294176.
    HOVERGENi HBG005255.
    InParanoidi A6QPZ5.
    KOi K04707.
    OMAi WQHSDSQ.
    OrthoDBi EOG73BVCF.
    TreeFami TF314210.

    Miscellaneous databases

    NextBioi 20899833.

    Family and domain databases

    Gene3Di 1.10.238.10. 1 hit.
    1.20.930.20. 1 hit.
    3.30.40.10. 1 hit.
    3.30.505.10. 1 hit.
    InterProi IPR024162. Adaptor_Cbl.
    IPR014741. Adaptor_Cbl_EF_hand-like.
    IPR003153. Adaptor_Cbl_N_hlx.
    IPR014742. Adaptor_Cbl_SH2-like.
    IPR024159. Cbl_PTB.
    IPR011992. EF-hand-dom_pair.
    IPR000980. SH2.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR017907. Znf_RING_CS.
    [Graphical view ]
    PANTHERi PTHR23007. PTHR23007. 1 hit.
    Pfami PF02262. Cbl_N. 1 hit.
    PF02761. Cbl_N2. 1 hit.
    PF02762. Cbl_N3. 1 hit.
    [Graphical view ]
    SMARTi SM00184. RING. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47668. SSF47668. 1 hit.
    SSF55550. SSF55550. 1 hit.
    PROSITEi PS51506. CBL_PTB. 1 hit.
    PS00518. ZF_RING_1. 1 hit.
    PS50089. ZF_RING_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: HerefordImported.
      Tissue: ThymusImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HerefordImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: HerefordImported.

    Entry informationi

    Entry nameiA6QPZ5_BOVIN
    AccessioniPrimary (citable) accession number: A6QPZ5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3