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A6QPZ5

- A6QPZ5_BOVIN

UniProt

A6QPZ5 - A6QPZ5_BOVIN

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Protein
Submitted name: CBLC protein
Gene
CBLC
Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. signal transducer activity Source: InterPro
  3. ubiquitin-protein transferase activity Source: Ensembl
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. cell surface receptor signaling pathway Source: InterPro
  2. negative regulation of MAP kinase activity Source: Ensembl
  3. negative regulation of epidermal growth factor-activated receptor activity Source: Ensembl
  4. protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
CBLC proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CBLCImported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 18

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000041264.

Structurei

3D structure databases

ProteinModelPortaliA6QPZ5.
SMRiA6QPZ5. Positions 13-319.

Family & Domainsi

Keywords - Domaini

Zinc-fingerUniRule annotation

Phylogenomic databases

eggNOGiNOG318595.
GeneTreeiENSGT00390000011617.
HOGENOMiHOG000294176.
HOVERGENiHBG005255.
InParanoidiA6QPZ5.
KOiK04707.
OMAiWQHSDSQ.
OrthoDBiEOG73BVCF.
TreeFamiTF314210.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
1.20.930.20. 1 hit.
3.30.40.10. 1 hit.
3.30.505.10. 1 hit.
InterProiIPR024162. Adaptor_Cbl.
IPR014741. Adaptor_Cbl_EF_hand-like.
IPR003153. Adaptor_Cbl_N_hlx.
IPR014742. Adaptor_Cbl_SH2-like.
IPR024159. Cbl_PTB.
IPR011992. EF-hand-dom_pair.
IPR000980. SH2.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR23007. PTHR23007. 1 hit.
PfamiPF02262. Cbl_N. 1 hit.
PF02761. Cbl_N2. 1 hit.
PF02762. Cbl_N3. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF47668. SSF47668. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS51506. CBL_PTB. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6QPZ5-1 [UniParc]FASTAAdd to Basket

« Hide

MAAAALRGRQ WGESRAFGRA VRLLQRLEEQ CGDPRLSSSP PSLRDLLPRT    50
AQLLRQVAQA RREAGGGVPE GPGGPWDFLM VYLANLEAKS RQVAALLPPH 100
GRKIANDELF REGSRLRRQL AKLALIFSYM HAELDALFPG GRYCGHTYQL 150
TKVSAHTFWR ERCGARCVLP WAEFEAVLCI CHPVEPGSTA LALRSTIDLT 200
CSGHVSIFEF DIFTRLFQPW PTLLKNWQLL AVNHPGYMAF LTYDEVQARL 250
QTFRDKPGSY IFRPSCTRLG KWAIGYVSSD GSILQTIPLN KPLFQVLLEG 300
QKEGFYLYPD GKNHNPDLTE LCHMEPHQHI HVSEEQLQLY WAMDSTFELC 350
KICAESNKDV KIEPCGHLLC SRCLAAWLCS DSQTCPFCRC EIKGQEAVSI 400
HQFHVSATVE DPEHSSDEEE LEQMAPSGPP LPPRLDLCPK SPSSKGHLNV 450
APPTLPRLRA PLPLPRFWTA ASAPWEVTSS PQAREGARGN S 491
Length:491
Mass (Da):54,955
Last modified:August 21, 2007 - v1
Checksum:iC3B9DD5706F88E66
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02047337 Genomic DNA. No translation available.
BC149567 mRNA. Translation: AAI49568.1.
RefSeqiNP_001094718.1. NM_001101248.2.
UniGeneiBt.21193.

Genome annotation databases

EnsembliENSBTAT00000043713; ENSBTAP00000041264; ENSBTAG00000009494.
GeneIDi615866.
KEGGibta:615866.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02047337 Genomic DNA. No translation available.
BC149567 mRNA. Translation: AAI49568.1 .
RefSeqi NP_001094718.1. NM_001101248.2.
UniGenei Bt.21193.

3D structure databases

ProteinModelPortali A6QPZ5.
SMRi A6QPZ5. Positions 13-319.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000041264.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000043713 ; ENSBTAP00000041264 ; ENSBTAG00000009494 .
GeneIDi 615866.
KEGGi bta:615866.

Organism-specific databases

CTDi 23624.

Phylogenomic databases

eggNOGi NOG318595.
GeneTreei ENSGT00390000011617.
HOGENOMi HOG000294176.
HOVERGENi HBG005255.
InParanoidi A6QPZ5.
KOi K04707.
OMAi WQHSDSQ.
OrthoDBi EOG73BVCF.
TreeFami TF314210.

Miscellaneous databases

NextBioi 20899833.

Family and domain databases

Gene3Di 1.10.238.10. 1 hit.
1.20.930.20. 1 hit.
3.30.40.10. 1 hit.
3.30.505.10. 1 hit.
InterProi IPR024162. Adaptor_Cbl.
IPR014741. Adaptor_Cbl_EF_hand-like.
IPR003153. Adaptor_Cbl_N_hlx.
IPR014742. Adaptor_Cbl_SH2-like.
IPR024159. Cbl_PTB.
IPR011992. EF-hand-dom_pair.
IPR000980. SH2.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view ]
PANTHERi PTHR23007. PTHR23007. 1 hit.
Pfami PF02262. Cbl_N. 1 hit.
PF02761. Cbl_N2. 1 hit.
PF02762. Cbl_N3. 1 hit.
[Graphical view ]
SMARTi SM00184. RING. 1 hit.
[Graphical view ]
SUPFAMi SSF47668. SSF47668. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEi PS51506. CBL_PTB. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HerefordImported.
    Tissue: ThymusImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiA6QPZ5_BOVIN
AccessioniPrimary (citable) accession number: A6QPZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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