Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutathione peroxidase 7

Gene

GPX7

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

2 glutathione + H2O2 = glutathione disulfide + 2 H2O.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei56By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase

Enzyme and pathway databases

ReactomeiR-BTA-3299685 Detoxification of Reactive Oxygen Species

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione peroxidase 7 (EC:1.11.1.9)
Short name:
GPx-7
Short name:
GSHPx-7
Gene namesi
Name:GPX7
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 3

Organism-specific databases

VGNCiVGNC:29621 GPX7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000031775419 – 186Glutathione peroxidase 7Add BLAST168

Proteomic databases

PaxDbiA6QLY2
PRIDEiA6QLY2

Expressioni

Gene expression databases

BgeeiENSBTAG00000018281

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000024329

Structurei

3D structure databases

ProteinModelPortaliA6QLY2
SMRiA6QLY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutathione peroxidase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1651 Eukaryota
COG0386 LUCA
GeneTreeiENSGT00760000119230
HOGENOMiHOG000277054
HOVERGENiHBG004333
InParanoidiA6QLY2
KOiK00432
OMAiIAQTCHI
OrthoDBiEOG091G0OJG
TreeFamiTF331942

Family and domain databases

CDDicd00340 GSH_Peroxidase, 1 hit
InterProiView protein in InterPro
IPR013376 Glut_perox_Gpx7
IPR000889 Glutathione_peroxidase
IPR029759 GPX_AS
IPR029760 GPX_CS
IPR036249 Thioredoxin-like_sf
PANTHERiPTHR11592 PTHR11592, 1 hit
PfamiView protein in Pfam
PF00255 GSHPx, 1 hit
PIRSFiPIRSF000303 Glutathion_perox, 1 hit
PRINTSiPR01011 GLUTPROXDASE
SUPFAMiSSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR02540 gpx7, 1 hit
PROSITEiView protein in PROSITE
PS00460 GLUTATHIONE_PEROXID_1, 1 hit
PS00763 GLUTATHIONE_PEROXID_2, 1 hit
PS51355 GLUTATHIONE_PEROXID_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6QLY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAARAAAWL LLAAAACAPR EQDFYDFKAV NIRGKLVSLE KYRGSVSLVV
60 70 80 90 100
NVASECGFTD QHYRALQQLQ RDLGPHHFNV LAFPCNQFGQ QEPDSNKEIE
110 120 130 140 150
SFARRTYSVS FPMFSKIAVT GTGAHPAFKY LTETSGKEPT WNFWKYLVAP
160 170 180
DGKVIGAWDP TVSVEEIRPQ ITALVRKLIL KKREDL
Length:186
Mass (Da):20,908
Last modified:August 21, 2007 - v1
Checksum:i6CADF950D7A02E28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC148128 mRNA Translation: AAI48129.1
RefSeqiNP_001094583.1, NM_001101113.2
UniGeneiBt.11662

Genome annotation databases

EnsembliENSBTAT00000024329; ENSBTAP00000024329; ENSBTAG00000018281
GeneIDi523311
KEGGibta:523311

Similar proteinsi

Entry informationi

Entry nameiGPX7_BOVIN
AccessioniPrimary (citable) accession number: A6QLY2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome