Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Secretogranin-3

Gene

SCG3

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-BTA-114608 Platelet degranulation
R-BTA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-BTA-8957275 Post-translational protein phosphorylation

Names & Taxonomyi

Protein namesi
Recommended name:
Secretogranin-3
Alternative name(s):
Secretogranin III
Short name:
SgIII
Gene namesi
Name:SCG3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 10

Organism-specific databases

VGNCiVGNC:34333 SCG3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicle, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000041702223 – 471Secretogranin-3Add BLAST449

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei40PhosphoserineBy similarity1
Glycosylationi71N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi353N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei365PhosphoserineBy similarity1

Keywords - PTMi

Cleavage on pair of basic residues, Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiA6QLI2
PRIDEiA6QLI2

Expressioni

Gene expression databases

BgeeiENSBTAG00000017677

Interactioni

Subunit structurei

Interacts with CHGA.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000023512

Structurei

3D structure databases

SMRiA6QLI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IHUH Eukaryota
ENOG4110KQ3 LUCA
GeneTreeiENSGT00390000005488
HOGENOMiHOG000247064
HOVERGENiHBG057085
InParanoidiA6QLI2
OMAiDLQYFPN
OrthoDBiEOG091G06X3
TreeFamiTF331266

Family and domain databases

InterProiView protein in InterPro
IPR026197 SCG3
PANTHERiPTHR17388 PTHR17388, 1 hit
PfamiView protein in Pfam
PF15467 SGIII, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6QLI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFLWTGTWI VVLMLHSSPI QAFPKPAGSQ DKPLHNRELS AERPLNEQIA
60 70 80 90 100
EAEADEIKKT YPPENKPGES NYSFVDNLNL LKAITEKEKN EKERQSVKIS
110 120 130 140 150
PNDNKLNVED VDSTKNRRLI DDYDSTKSGL DRKFQDDPDG LHQLDGTPLT
160 170 180 190 200
AEDIVQKIAT RIYEENDRGV FDRIVSKLLN LGLITESQAH TLEDEVAEVL
210 220 230 240 250
QKLISKEANN YEEELNKPTS KTESQTGKIP EKVTPMAAIQ DAFTNGENDE
260 270 280 290 300
TVSNTLTLTN GLERRTKTYS EDNFEELQYF PNFYALLKSI DSEKEAKEKE
310 320 330 340 350
TLITIMKTLI DFVKMMVKYG TISPEEGVSY LENLDETIAL QTKNKLEKNV
360 370 380 390 400
TDNKSKLFAV PSEKSHEETD STKEEAAKME KEYGTLKDST KDDDSNPRGK
410 420 430 440 450
TDEHKGKTEA YLEAIRKNID WLKKHNKKEN KEDYDLSKMR DFINQQADAY
460 470
VEKGILDKEE ADAIKRIYSS L
Length:471
Mass (Da):53,751
Last modified:August 21, 2007 - v1
Checksum:i267A1E8AA89E70F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02029009 Genomic DNA No translation available.
DAAA02029010 Genomic DNA No translation available.
DAAA02029011 Genomic DNA No translation available.
BC147974 mRNA Translation: AAI47975.1
RefSeqiNP_001095567.1, NM_001102097.1
UniGeneiBt.42407

Genome annotation databases

EnsembliENSBTAT00000023512; ENSBTAP00000023512; ENSBTAG00000017677
GeneIDi525941
KEGGibta:525941

Similar proteinsi

Entry informationi

Entry nameiSCG3_BOVIN
AccessioniPrimary (citable) accession number: A6QLI2
Secondary accession number(s): F1MY56
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2012
Last sequence update: August 21, 2007
Last modified: March 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health