A6QLB8 (A6QLB8_BOVIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GSK3A protein EMBL AAI47909.1

Submitted name:
Uncharacterized protein Ensembl ENSBTAP00000027660

Gene names

Name:

GSK3A Ensembl ENSBTAP00000027660 EMBL AAI47909.1

Organism

Bos taurus (Bovine) [Reference proteome]

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	495 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cardiac left ventricle morphogenesis Inferred from electronic annotation. Source: Compara cell migration Inferred from electronic annotation. Source: Compara cellular response to lithium ion Inferred from electronic annotation. Source: Compara cellular response to organic cyclic compound Inferred from electronic annotation. Source: Compara hypermethylation of CpG island Inferred from electronic annotation. Source: Compara insulin receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of TOR signaling cascade Inferred from electronic annotation. Source: Compara negative regulation of cell growth involved in cardiac muscle cell development Inferred from electronic annotation. Source: Compara negative regulation of glucose import Inferred from electronic annotation. Source: Compara negative regulation of insulin receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of transferase activity Inferred from electronic annotation. Source: Compara positive regulation of adrenergic receptor signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of cAMP biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of glycogen (starch) synthase activity Inferred from electronic annotation. Source: Compara positive regulation of heart contraction Inferred from electronic annotation. Source: Compara positive regulation of peptidyl-serine phosphorylation Inferred from electronic annotation. Source: Compara positive regulation of peptidyl-threonine phosphorylation Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara regulation of gene expression by genetic imprinting Inferred from electronic annotation. Source: Compara regulation of systemic arterial blood pressure Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6QLB8 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: DC13D3A3922F51C8	FASTA	495	52,263
	10 20 30 40 50 60 MSGGAPSGGG PGGSGRARTS SFAEPGGGGG GGGGGPGGSA SGPGGSGGGK TSVGAMGGGV 70 80 90 100 110 120 GASSSGGGPG GSGGGGSGGP GAGTSFPPPG VKLGRDSGKV TTVVATLGQG PERSQEVAYT 130 140 150 160 170 180 DIKVIGSGSF GVVYQARLAD TRELVAIKKV LQDKRFKNRE LQIMRKLDHC NIVRLRYFFY 190 200 210 220 230 240 SSGEKKDELY LNLVLEYVPE TVYRVARHFT KAKLSIPIIY VKVYMYQLFR SLAYIHSQGV 250 260 270 280 290 300 CHRDIKPQNL LVDPDTAVLK LCDFGSAKQL VRGEPNVSYI CSRYYRAPEL IFGATDYTSS 310 320 330 340 350 360 IDVWSAGCVL AELLLGQPIF PGDSGVDQLV EIIKVLGTPS REQIREMNPN YTEFKFPQIK 370 380 390 400 410 420 AHPWTKVFKS RTPPEAIALC SSLLEYTPSS RLSPLEACAH SFFDELRCPG TQLPNNRPLP 430 440 450 460 470 480 PLFNFSPGEL TIQPSLNAIL IPPHLRSPAG TASLTPSSQA LSEAQTSSDW QSTDNTATLP 490 PGLHLLQPPH LLCPL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y., Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C., Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J. , Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J., Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A., Holt R., Jones S.J., Marra M.A. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: L1 Hereford EMBL AAI47909.1. Tissue: Uterus EMBL AAI47909.1.
[2]	"A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol. 10:R42-R42(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hereford Ensembl ENSBTAP00000027660.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Hereford Ensembl ENSBTAP00000027660.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DAAA02047214 Genomic DNA. No translation available. DAAA02047215 Genomic DNA. No translation available. BC147908 mRNA. Translation: AAI47909.1.
IPI	IPI00866989.
RefSeq	NP_001095662.1. NM_001102192.1.
UniGene	Bt.33944.
3D structure databases
SMR	A6QLB8. Positions 99-446.
ModBase	Search...
Protein-protein interaction databases
STRING	9913.ENSBTAP00000027660.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000027660; ENSBTAP00000027660; ENSBTAG00000020756.
GeneID	536561.
KEGG	bta:536561.
Organism-specific databases
CTD	2931.
Phylogenomic databases
eggNOG	COG0515.
GeneTree	ENSGT00520000055635.
HOGENOM	HOG000233017.
HOVERGEN	HBG014652.
InParanoid	A6QLB8.
KO	K08822.
OMA	FDELRCP.
OrthoDB	EOG4WH8KZ.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20876974.

Entry information

Entry name

A6QLB8_BOVIN

Accession

Primary (citable) accession number: A6QLB8
Secondary accession number(s): F1MHW8

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	April 3, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)