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Protein
Submitted name:

CCR4 protein

Gene

CCR4

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-BTA-380108. Chemokine receptors bind chemokines.
R-BTA-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
CCR4 proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CCR4Imported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 22

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei45 – 6521HelicalSequence analysisAdd
BLAST
Transmembranei77 – 10024HelicalSequence analysisAdd
BLAST
Transmembranei112 – 13019HelicalSequence analysisAdd
BLAST
Transmembranei151 – 17424HelicalSequence analysisAdd
BLAST
Transmembranei200 – 22223HelicalSequence analysisAdd
BLAST
Transmembranei243 – 26422HelicalSequence analysisAdd
BLAST
Transmembranei284 – 30724HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSBTAG00000034883.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000046254.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 304249G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118785.
HOGENOMiHOG000234122.
HOVERGENiHBG106917.
KOiK04179.
OMAiKFRKYIV.
OrthoDBiEOG091G0B7A.
TreeFamiTF330966.

Family and domain databases

InterProiIPR002239. Chemokine_CCR4.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01109. CHEMOKINER4.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6QLA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPTDIADTT VDESIYNSYY LYENLPKPCN KDGIRAFGGL FLPPLYSLVF
60 70 80 90 100
LFGLLGNSVV VLVLFKYKRL KSMTDVYLLN LAISDLLFVL SLPFWGYYAA
110 120 130 140 150
DQWVFGLGLC KLISWIYLVG FYSGIFFITL MSIDRYLAIV HAIFSLRART
160 170 180 190 200
LTYGVITSVA TWSVAVLVSL PGLLFSTCYT ERNHTYCKTK YSFNSTRWKV
210 220 230 240 250
LSSLEINILG LVIPLGIMLF CYSMIIRTLQ HCKNEKKNKA VKMIFAVVVL
260 270 280 290 300
FLGFWTPYNV VLFLETLVEL EVLQDCTFER HLDYAIQTTE TLAFVHCCLN
310 320 330 340 350
PVIYFFLGEK FRKYIVQLFK TCRGTLVLCQ YCRLLPMYTD TPSSSYTQST

VDHDLRDAL
Length:359
Mass (Da):41,252
Last modified:August 21, 2007 - v1
Checksum:iD6F29CE330D919A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02053580 Genomic DNA. No translation available.
BC147895 mRNA. Translation: AAI47896.1.
RefSeqiNP_001093763.1. NM_001100293.2.
UniGeneiBt.29981.

Genome annotation databases

EnsembliENSBTAT00000049352; ENSBTAP00000046254; ENSBTAG00000034883.
GeneIDi408019.
KEGGibta:408019.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02053580 Genomic DNA. No translation available.
BC147895 mRNA. Translation: AAI47896.1.
RefSeqiNP_001093763.1. NM_001100293.2.
UniGeneiBt.29981.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000046254.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000049352; ENSBTAP00000046254; ENSBTAG00000034883.
GeneIDi408019.
KEGGibta:408019.

Organism-specific databases

CTDi1233.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118785.
HOGENOMiHOG000234122.
HOVERGENiHBG106917.
KOiK04179.
OMAiKFRKYIV.
OrthoDBiEOG091G0B7A.
TreeFamiTF330966.

Enzyme and pathway databases

ReactomeiR-BTA-380108. Chemokine receptors bind chemokines.
R-BTA-418594. G alpha (i) signalling events.

Gene expression databases

BgeeiENSBTAG00000034883.

Family and domain databases

InterProiIPR002239. Chemokine_CCR4.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01109. CHEMOKINER4.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA6QLA5_BOVIN
AccessioniPrimary (citable) accession number: A6QLA5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.