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Protein
Submitted name:

APLNR protein

Gene

APLNR

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-BTA-375276. Peptide ligand-binding receptors.
R-BTA-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
APLNR proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:APLNRImported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 15

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei33 – 5422HelicalSequence analysisAdd
BLAST
Transmembranei66 – 8621HelicalSequence analysisAdd
BLAST
Transmembranei106 – 12520HelicalSequence analysisAdd
BLAST
Transmembranei146 – 16722HelicalSequence analysisAdd
BLAST
Transmembranei210 – 22819HelicalSequence analysisAdd
BLAST
Transmembranei249 – 26921HelicalSequence analysisAdd
BLAST
Transmembranei289 – 31527HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000039331.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 312268G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000119055.
HOGENOMiHOG000234122.
HOVERGENiHBG104998.
KOiK04174.
OMAiVMVFRST.
OrthoDBiEOG7Z0JWM.
TreeFamiTF330024.

Family and domain databases

InterProiIPR003904. APJ_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01416. APJRECEPTOR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6QL98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEGGEYDGY YGADNQSECE YEDWQSSGAL IPAIYMVVFV LGTAGNGLVL
60 70 80 90 100
WTIFRSGRDR RRAADVFIAS LAVADLTFVV TLPLWATYTY RDYDWPFGAF
110 120 130 140 150
ACKLSSYLIF VNMYASVFCL TGLSLDRYLA IVRPVANARL RPRVGGAVAT
160 170 180 190 200
AGLWALAGLL ALPVLVFRAT STVLQAENAT KVQCYMDYSL VAGPDAEWAW
210 220 230 240 250
EVGLGVSSTA LGFAGPFAVM LTCYFCIGRT VAGHFGKERA RGLRKRRRLL
260 270 280 290 300
AIIAVLVLTF ALCWLPYHLV KTLYVLGSLL RWPCAFDLFL MNVFPYCTCV
310 320 330 340 350
SYVNSCLNPF LYAFFDPRFR QACASVLCWG RRGCGGAWRA GGGGGGGGGR
360 370 380 390 400
GGGGGDKSAS SSSSASSGHS QGPGPGGAGK GGEPMPEKSI PYSQETLLVD
Length:400
Mass (Da):43,006
Last modified:August 21, 2007 - v1
Checksum:i4FB1F03B08390384
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02041720 Genomic DNA. No translation available.
BC147888 mRNA. Translation: AAI47889.1.
RefSeqiNP_001095994.1. NM_001102524.2.
UniGeneiBt.26604.

Genome annotation databases

EnsembliENSBTAT00000039541; ENSBTAP00000039331; ENSBTAG00000027516.
GeneIDi615435.
KEGGibta:615435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02041720 Genomic DNA. No translation available.
BC147888 mRNA. Translation: AAI47889.1.
RefSeqiNP_001095994.1. NM_001102524.2.
UniGeneiBt.26604.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000039331.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000039541; ENSBTAP00000039331; ENSBTAG00000027516.
GeneIDi615435.
KEGGibta:615435.

Organism-specific databases

CTDi187.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000119055.
HOGENOMiHOG000234122.
HOVERGENiHBG104998.
KOiK04174.
OMAiVMVFRST.
OrthoDBiEOG7Z0JWM.
TreeFamiTF330024.

Enzyme and pathway databases

ReactomeiR-BTA-375276. Peptide ligand-binding receptors.
R-BTA-418594. G alpha (i) signalling events.

Family and domain databases

InterProiIPR003904. APJ_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01416. APJRECEPTOR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HerefordImported.
    Tissue: HypothalamusImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  3. Ensembl
    Submitted (MAR-2016) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiA6QL98_BOVIN
AccessioniPrimary (citable) accession number: A6QL98
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: June 8, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.