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Protein

Copper chaperone CopZ

Gene

copZ

Organism
Staphylococcus aureus (strain Newman)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Chaperone that serves for the intracellular sequestration and transport of Cu+. Delivers Cu+ to the copper-exporting P-type ATPase A (CopA) (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi13CopperPROSITE-ProRule annotation1
Metal bindingi16CopperPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Copper chaperone CopZ
Gene namesi
Name:copZ
Ordered Locus Names:NWMN_2458
OrganismiStaphylococcus aureus (strain Newman)
Taxonomic identifieri426430 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000006386 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003512811 – 68Copper chaperone CopZAdd BLAST68

Structurei

3D structure databases

ProteinModelPortaliA6QK48.
SMRiA6QK48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 68HMAPROSITE-ProRule annotationAdd BLAST66

Phylogenomic databases

HOGENOMiHOG000038877.
KOiK07213.
OMAiNHCVKAV.

Family and domain databases

CDDicd00371. HMA. 1 hit.
InterProiView protein in InterPro
IPR017969. Heavy-metal-associated_CS.
IPR006122. HMA_Cu_ion-bd.
IPR006121. HMA_dom.
IPR001802. MerP/CopZ.
PfamiView protein in Pfam
PF00403. HMA. 1 hit.
PRINTSiPR00946. HGSCAVENGER.
SUPFAMiSSF55008. SSF55008. 1 hit.
TIGRFAMsiTIGR00003. TIGR00003. 1 hit.
PROSITEiView protein in PROSITE
PS01047. HMA_1. 1 hit.
PS50846. HMA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A6QK48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQEILNVEG MSCGHCKSAV ESALNNIDGV TSADVNLENG QVSVQYDDSK
60
VAVSQMKDAI EDQGYDVV
Length:68
Mass (Da):7,237
Last modified:August 21, 2007 - v1
Checksum:iD8DC0D1349C1BF3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009351 Genomic DNA. Translation: BAF68730.1.
RefSeqiWP_000076661.1. NC_009641.1.

Genome annotation databases

EnsemblBacteriaiBAF68730; BAF68730; NWMN_2458.
KEGGisae:NWMN_2458.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCOPZ_STAAE
AccessioniPrimary (citable) accession number: A6QK48
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: August 21, 2007
Last modified: June 7, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome