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Protein

Ferredoxin--NADP reductase

Gene

NWMN_2274

Organism
Staphylococcus aureus (strain Newman)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12FADUniRule annotation1
Binding sitei31FADUniRule annotation1
Binding sitei39FADUniRule annotation1
Binding sitei43FADUniRule annotation1
Binding sitei83FAD; via amide nitrogen and carbonyl oxygenUniRule annotation1
Binding sitei118FAD; via amide nitrogenUniRule annotation1
Binding sitei285FADUniRule annotation1
Binding sitei326FADUniRule annotation1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein, NADP

Enzyme and pathway databases

BioCyciSAUR426430:GIXC-2346-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin--NADP reductaseUniRule annotation (EC:1.18.1.2UniRule annotation)
Short name:
FNRUniRule annotation
Short name:
Fd-NADP(+) reductaseUniRule annotation
Gene namesi
Ordered Locus Names:NWMN_2274
OrganismiStaphylococcus aureus (strain Newman)
Taxonomic identifieri426430 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000006386 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003649451 – 344Ferredoxin--NADP reductaseAdd BLAST344

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA6QJL4.
SMRiA6QJL4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ferredoxin--NADP reductase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000072909.
KOiK00384.
OMAiKSERHFE.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_01685. FENR2. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSiPR00469. PNDRDTASEII.
SUPFAMiSSF51905. SSF51905. 1 hit.

Sequencei

Sequence statusi: Complete.

A6QJL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDVTIIGGG PSGLYASFYA GLRDMSVRLI DVQSELGGKM RIYPEKIIWD
60 70 80 90 100
IGGIAPKPCH EILKDTIKQG LYFKPEVHLN ERVVDIRKKA ERHFEVETEA
110 120 130 140 150
GEIYTSKAVI IAIGAGIINP KQLDVKGVER YQLTNLHYVV QSYRRFKDKD
160 170 180 190 200
VLISGGGNTA LDWAHDIAKI AKSVTVVYRK EDVSGHEAMK TLVTDLNVKL
210 220 230 240 250
CPKTRIKYLV GNDDETHISE VVLEHVESGD RHTVKFDDVI ISHGFDRCNT
260 270 280 290 300
LLSETSSKLD MHDDCRVKGF GNTTTSIPGI YACGDIVYHD AKSHLIASAF
310 320 330 340
SDGANAANLA KTYIQPDANA EGYVSSHHEV FKEANKTIVN KHLY
Length:344
Mass (Da):38,230
Last modified:August 21, 2007 - v1
Checksum:i46E1A319359751D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009351 Genomic DNA. Translation: BAF68546.1.
RefSeqiWP_000655971.1. NC_009641.1.

Genome annotation databases

EnsemblBacteriaiBAF68546; BAF68546; NWMN_2274.
GeneIDi28380016.
KEGGisae:NWMN_2274.
PATRICi19588393. VBIStaAur133992_2472.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009351 Genomic DNA. Translation: BAF68546.1.
RefSeqiWP_000655971.1. NC_009641.1.

3D structure databases

ProteinModelPortaliA6QJL4.
SMRiA6QJL4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAF68546; BAF68546; NWMN_2274.
GeneIDi28380016.
KEGGisae:NWMN_2274.
PATRICi19588393. VBIStaAur133992_2472.

Phylogenomic databases

HOGENOMiHOG000072909.
KOiK00384.
OMAiKSERHFE.

Enzyme and pathway databases

BioCyciSAUR426430:GIXC-2346-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_01685. FENR2. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSiPR00469. PNDRDTASEII.
SUPFAMiSSF51905. SSF51905. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFENR_STAAE
AccessioniPrimary (citable) accession number: A6QJL4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: August 21, 2007
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.