Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ferredoxin--NADP reductase

Gene

NWMN_2274

Organism
Staphylococcus aureus (strain Newman)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei12 – 121FADUniRule annotation
Binding sitei31 – 311FADUniRule annotation
Binding sitei39 – 391FADUniRule annotation
Binding sitei43 – 431FADUniRule annotation
Binding sitei83 – 831FAD; via amide nitrogen and carbonyl oxygenUniRule annotation
Binding sitei118 – 1181FAD; via amide nitrogenUniRule annotation
Binding sitei285 – 2851FADUniRule annotation
Binding sitei326 – 3261FADUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein, NADP

Enzyme and pathway databases

BioCyciSAUR426430:GIXC-2347-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin--NADP reductaseUniRule annotation (EC:1.18.1.2UniRule annotation)
Short name:
FNRUniRule annotation
Short name:
Fd-NADP(+) reductaseUniRule annotation
Gene namesi
Ordered Locus Names:NWMN_2274
OrganismiStaphylococcus aureus (strain Newman)
Taxonomic identifieri426430 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000006386 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 344344Ferredoxin--NADP reductasePRO_0000364945Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA6QJL4.
SMRiA6QJL4. Positions 3-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ferredoxin--NADP reductase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000072909.
KOiK00384.
OMAiKSERHFE.
OrthoDBiEOG661H9M.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_01685. FENR2.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSiPR00469. PNDRDTASEII.
SUPFAMiSSF51905. SSF51905. 1 hit.

Sequencei

Sequence statusi: Complete.

A6QJL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDVTIIGGG PSGLYASFYA GLRDMSVRLI DVQSELGGKM RIYPEKIIWD
60 70 80 90 100
IGGIAPKPCH EILKDTIKQG LYFKPEVHLN ERVVDIRKKA ERHFEVETEA
110 120 130 140 150
GEIYTSKAVI IAIGAGIINP KQLDVKGVER YQLTNLHYVV QSYRRFKDKD
160 170 180 190 200
VLISGGGNTA LDWAHDIAKI AKSVTVVYRK EDVSGHEAMK TLVTDLNVKL
210 220 230 240 250
CPKTRIKYLV GNDDETHISE VVLEHVESGD RHTVKFDDVI ISHGFDRCNT
260 270 280 290 300
LLSETSSKLD MHDDCRVKGF GNTTTSIPGI YACGDIVYHD AKSHLIASAF
310 320 330 340
SDGANAANLA KTYIQPDANA EGYVSSHHEV FKEANKTIVN KHLY
Length:344
Mass (Da):38,230
Last modified:August 21, 2007 - v1
Checksum:i46E1A319359751D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009351 Genomic DNA. Translation: BAF68546.1.
RefSeqiWP_000655971.1. NC_009641.1.

Genome annotation databases

EnsemblBacteriaiBAF68546; BAF68546; NWMN_2274.
KEGGisae:NWMN_2274.
PATRICi19588393. VBIStaAur133992_2472.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009351 Genomic DNA. Translation: BAF68546.1.
RefSeqiWP_000655971.1. NC_009641.1.

3D structure databases

ProteinModelPortaliA6QJL4.
SMRiA6QJL4. Positions 3-321.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAF68546; BAF68546; NWMN_2274.
KEGGisae:NWMN_2274.
PATRICi19588393. VBIStaAur133992_2472.

Phylogenomic databases

HOGENOMiHOG000072909.
KOiK00384.
OMAiKSERHFE.
OrthoDBiEOG661H9M.

Enzyme and pathway databases

BioCyciSAUR426430:GIXC-2347-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_01685. FENR2.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSiPR00469. PNDRDTASEII.
SUPFAMiSSF51905. SSF51905. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands."
    Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K.
    J. Bacteriol. 190:300-310(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Newman.

Entry informationi

Entry nameiFENR_STAAE
AccessioniPrimary (citable) accession number: A6QJL4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: August 21, 2007
Last modified: March 16, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.