A6QJ33 (LACG_STAAE) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 35.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 6-phospho-beta-galactosidase EC=3.2.1.85 Alternative name(s): Beta-D-phosphogalactoside galactohydrolase Short name=PGALase P-beta-Gal Short name=PBG | ||||
| Gene names |
| ||||
| Organism | Staphylococcus aureus (strain Newman) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 426430 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 470 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol. HAMAP MF_01574 |
| Pathway | Carbohydrate metabolism; lactose degradation; D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate: step 1/1. HAMAP MF_01574 |
| Sequence similarities | Belongs to the glycosyl hydrolase 1 family. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Glycosidase Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | lactose catabolic process via tagatose-6-phosphate Inferred from electronic annotation. Source: InterPro |
| Molecular function | 6-phospho-beta-galactosidase activity Inferred from electronic annotation. Source: EC cation bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 470 | 470 | 6-phospho-beta-galactosidase HAMAP MF_01574 | PRO_1000073602 | |||||
Sites | |||||||||
| Active site | 160 | 1 | Proton donor By similarity | ||||||
| Active site | 375 | 1 | Nucleophile By similarity | ||||||
Sequences
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References
| [1] | "Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands." Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K. J. Bacteriol. 190:300-310(2008) [PubMed: 17951380] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Newman. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AP009351 Genomic DNA. Translation: BAF68365.1. |
| RefSeq | YP_001333127.1. NC_009641.1. |
3D structure databases | |
| ProteinModelPortal | A6QJ33. |
| SMR | A6QJ33. Positions 1-470. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A6QJ33. |
Protein family/group databases | |
| CAZy | GH1. Glycoside Hydrolase Family 1. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBSTAT00000032302; EBSTAP00000031172; EBSTAG00000032300. |
| GeneID | 5331285. |
| GenomeReviews | Gene locus NWMN_2093 in contig AP009351_GR. |
| KEGG | sae:NWMN_2093. |
| PATRIC | 19588007. VBIStaAur133992_2279. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG2723. |
| GeneTree | EBGT00050000024342. |
| HOGENOM | HBG316462. |
| OMA | FVNYAEF. |
| ProtClustDB | PRK13511. |
Enzyme and pathway databases | |
| BioCyc | SAUR426430:NWMN_2093-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01574. LacG. [Tree] |
| InterPro | IPR005928. 6P-beta-galactosidase. IPR001360. Glyco_hydro_1. IPR018120. Glyco_hydro_1_AS. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view] |
| Gene3D | G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit. |
| KO | K01220. |
| PANTHER | PTHR10353. Glyco_hydro_1. 1 hit. |
| Pfam | PF00232. Glyco_hydro_1. 1 hit. [Graphical view] |
| PRINTS | PR00131. GLHYDRLASE1. |
| SUPFAM | SSF51445. Glyco_hydro_cat. 1 hit. |
| TIGRFAMs | TIGR01233. LacG. 1 hit. |
| PROSITE | PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit. PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | LACG_STAAE | ||||||||
| Accession | Primary (citable) accession number: A6QJ33 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Glycosyl hydrolases Classification of glycosyl hydrolase families and list of entries |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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