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A6QIS1 (ATKB_STAAE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Potassium-transporting ATPase B chain
EC=3.6.3.12
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chain
Potassium-binding and translocating subunit B
Potassium-translocating ATPase B chain
Gene names
Name:kdpB
Ordered Locus Names:NWMN_1981
OrganismStaphylococcus aureus (strain Newman) [Complete proteome] [HAMAP]
Taxonomic identifier426430 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length675 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions By similarity. HAMAP-Rule MF_00285

Catalytic activity

ATP + H2O + K+(Out) = ADP + phosphate + K+(In). HAMAP-Rule MF_00285

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00285.

Sequence similarities

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 675675Potassium-transporting ATPase B chain HAMAP-Rule MF_00285
PRO_1000071940

Regions

Transmembrane34 – 5421Helical; Potential
Transmembrane65 – 8521Helical; Potential
Transmembrane216 – 23621Helical; Potential
Transmembrane245 – 26521Helical; Potential
Transmembrane569 – 59123Helical; Potential
Transmembrane611 – 63121Helical; Potential
Transmembrane644 – 66421Helical; Potential

Sites

Active site30414-aspartylphosphate intermediate By similarity
Metal binding5131Magnesium By similarity
Metal binding5171Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
A6QIS1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 78F1466C0D60425B

FASTA67573,153
        10         20         30         40         50         60 
MHHVNKYFNQ TMVIEALKMS FYKLNLKQLI KNPIMFVVEV GMILTLILIC FPDIFGTSYL 

        70         80         90        100        110        120 
SRGYLITIFI ILLITILFAN FSEAFAEGRG KAQADSLRQA QSNLTARLIE ENGAYRIVNA 

       130        140        150        160        170        180 
TELKAGQNIR VENGETIPAD GVVINGLATV DESAITGESA PVIKESGGDF DGVIGGTLVT 

       190        200        210        220        230        240 
SDWLEIRVES EAGTSFLDKM IALVEGAERN KTPNEIALFT LLTTLTIIFL VVIVTLYPIA 

       250        260        270        280        290        300 
SYLHLILPIA MLIALTVCLI PTTIGGLLSA IGIAGMDRVT QFNVLAKSGR AVEVCGDVDV 

       310        320        330        340        350        360 
MILDKTGTIT YGNRIASEFL PVNQQMLEKL IVAAYMSSIY DDTPEGKSIV RLAKQMYINE 

       370        380        390        400        410        420 
LPKDIDGTYK PFTAETRMSG IITNEISVFK GAPNSMINLV KQQQGNIPLN IESLCMDVSS 

       430        440        450        460        470        480 
KGGTPLIVIE NNVMLGVIYL KDVIKDGLVE RFTELRKMGI ETVMCTGDNA LTAATIAKEA 

       490        500        510        520        530        540 
GVDRFVAECK PEDKIKVIKD EQAKGHIVAM TGDGTNDAPA LAQANIGLAM NSGTISAKEA 

       550        560        570        580        590        600 
ANLIDLDSNP TKLIEVVKIG KQLLMTRGAL TTFSLANDVA KYFAILPALM MSTIPEMTSL 

       610        620        630        640        650        660 
NIMHLSSPKS AIISALIFNA LIIVALIPIA MKGVKVKGYS IDRIFINNML IYGLGGLIVP 

       670 
FLGIKLIDMI VQFFV

« Hide

References

[1]"Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands."
Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K.
J. Bacteriol. 190:300-310(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Newman.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009351 Genomic DNA. Translation: BAF68253.1.
RefSeqYP_001333015.1. NC_009641.1.

3D structure databases

ProteinModelPortalA6QIS1.
ModBaseSearch...

Protein-protein interaction databases

STRING426430.NWMN_1981.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF68253; BAF68253; NWMN_1981.
GeneID5332062.
KEGGsae:NWMN_1981.
PATRIC19587766. VBIStaAur133992_2168.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2216.
HOGENOMHOG000244113.
KOK01547.
OMAKADERES.
ProtClustDBPRK01122.

Enzyme and pathway databases

BioCycSAUR426430:GIXC-1982-MONOMER.

Family and domain databases

Gene3D2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
HAMAPMF_00285. KdpB.
InterProIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
IPR006391. K-transp_ATPase_bsu_IA.
[Graphical view]
PANTHERPTHR24093. PTHR24093. 1 hit.
PfamPF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01494. ATPase_P-type. 2 hits.
TIGR01497. kdpB. 1 hit.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATKB_STAAE
AccessionPrimary (citable) accession number: A6QIS1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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