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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Staphylococcus aureus (strain Newman)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:NWMN_1428
OrganismiStaphylococcus aureus (strain Newman)
Taxonomic identifieri426430 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000006386 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000721631 – 445Exodeoxyribonuclease 7 large subunitAdd BLAST445

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Structurei

3D structure databases

SMRiA6QH68
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229265
KOiK03601
OMAiNARRRWP

Family and domain databases

CDDicd04489 ExoVII_LU_OBF, 1 hit
HAMAPiMF_00378 Exonuc_7_L, 1 hit
InterProiView protein in InterPro
IPR003753 Exonuc_VII_L
IPR020579 Exonuc_VII_lsu_C
IPR025824 OB-fold_nuc-bd_dom
PANTHERiPTHR30008 PTHR30008, 1 hit
PfamiView protein in Pfam
PF02601 Exonuc_VII_L, 1 hit
PF13742 tRNA_anti_2, 1 hit
TIGRFAMsiTIGR00237 xseA, 1 hit

Sequencei

Sequence statusi: Complete.

A6QH68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDYLSVSAL TKYIKYKFDQ DPHLQSVLIK GELSNFKKHS SGHLYFNVKD
60 70 80 90 100
KESVISAMMF KGSASKLNFE PKEGDEVLLE ARVSVFERRG NYQIYVNKMQ
110 120 130 140 150
LDGIGNLYQK LEALKKKLTE EGCFDKANKK SIPKFPKKIA VLTASTGAAI
160 170 180 190 200
RDIHSTINSR FPLAEQIQIS TLVQGEKAKD DIIEKIEYAD SLGVDTIIVG
210 220 230 240 250
RGGGSIEDLW NFNEEAVVRA IYNCKTPIIS AVGHETDFTL SDFAADIRAA
260 270 280 290 300
TPTQAAVIAT PDQYELLQQI QQYQFTLTRF IKKHLEQQRK HVEHLSSYYK
310 320 330 340 350
FKQPTLLYDQ QIQRRDDLEK RLKQQIQATF EQQRHRLMLL QQRYNLKALL
360 370 380 390 400
SSVNQEQQNN LQLTNQLVKL LNSKILSYKN DLKNKVENLN NLSPTNTMLR
410 420 430 440
GYAIVNKKDE VITSTKDLTE NDQLTLTMKD GLVDAKVTKV RCNND
Length:445
Mass (Da):50,894
Last modified:August 21, 2007 - v1
Checksum:i172C12F9B18EA4EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009351 Genomic DNA Translation: BAF67700.1
RefSeqiWP_001286928.1, NZ_CP023390.1

Genome annotation databases

EnsemblBacteriaiBAF67700; BAF67700; NWMN_1428
KEGGisae:NWMN_1428

Similar proteinsi

Entry informationi

Entry nameiEX7L_STAAE
AccessioniPrimary (citable) accession number: A6QH68
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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