A6QEK4 (ARAB_STAAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribulokinase
EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	NWMN_0514

Organism

Staphylococcus aureus (strain Newman) [Complete proteome] [HAMAP]

Taxonomic identifier

426430 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	545 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 545	545	Ribulokinase HAMAP MF_00520		PRO_1000072490

Sequences

	Sequence		Length	Mass (Da)
	A6QEK4 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 2959445FC3DA3EEB	FASTA	545	61,011
	10 20 30 40 50 60 MSYSIGIDYG TASGRVFLIN TTNGQVVSKF VKPYTHGVIE SELNGLKIPH TYALQNSNDY 70 80 90 100 110 120 LEIMEEGISY IVRESKIDPD NIVGIGIDFT SSTIIFTDEN LNPVHNLKQF KNNPHAYVKL 130 140 150 160 170 180 WKHHGAYKEA EKLYQTAIEN NNKWLGHYGY NVSSEWMIPK IMEVMNRAPE IMEKTAYIME 190 200 210 220 230 240 AGDWIVNKLT NKNVRSNCGL GFKAFWEEET GFHYDLFDKI DPKLSKVIQD KVSAPVVNIG 250 260 270 280 290 300 EAVGKLDDKM AQKLGLSKET MVSPFIIDAH ASLLGIGSEK DKEMTMVMGT STCHLMLNEK 310 320 330 340 350 360 QHQVPGISGS VKGAIIPELF AYEAGQSAVG DLFEYVAKQA PKSYVDEAEN RNMTVFELMN 370 380 390 400 410 420 EKIKHQMPGE SGLIALDWHN GNRSVLSDSN LTGCIFGLTL QTKHEDIYRA YLEATAFGTK 430 440 450 460 470 480 MIMQQYQDWH MEVEKVFACG GIPKKNAVMM DIYANVLNKK LIVMDSEYAP AIGAAILGAV 490 500 510 520 530 540 SGGAHNSIND AVDAMKEPIL YEINPEAEKV QRYETLFKAY KALHDIHGYK KANIMKDIQS LRVEG

References

[1]

"Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands." Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K. J. Bacteriol. 190:300-310(2008) [PubMed: 17951380] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Newman.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009351 Genomic DNA. Translation: BAF66786.1.
RefSeq	YP_001331548.1. NC_009641.1.
3D structure databases
ProteinModelPortal	A6QEK4.
ModBase	Search...
Protein-protein interaction databases
STRING	A6QEK4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000030876; EBSTAP00000029746; EBSTAG00000030874.
GeneID	5330269.
GenomeReviews	Gene locus NWMN_0514 in contig AP009351_GR.
KEGG	sae:NWMN_0514.
PATRIC	19584470. VBIStaAur133992_0561.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1069.
GeneTree	EBGT00050000024725.
HOGENOM	HBG312681.
OMA	NGRRTPD.
ProtClustDB	PRK04123.
Enzyme and pathway databases
BioCyc	SAUR426430:NWMN_0514-MONOMER.
Family and domain databases
HAMAP	MF_00520. Ribulokinase. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
KO	K00853.
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARAB_STAAE

Accession

Primary (citable) accession number: A6QEK4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program